PubMed

Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA.

Diabetes. 2009 Jan;58(1):39-45. Epub 2008 Oct 13. Erratum in: Diabetes. 2009 Aug;58(8):1936. PMID: 18852327 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA.

Diabetes. 2006 Nov;55(11):3013-9.PMID: 17065337 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson CM, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2004 Aug;53(8):2051-9.PMID: 15277385 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson MC, Toffolo G, Cobelli C, Rizza RA.

J Clin Endocrinol Metab. 2005 Jul;90(7):3919-26. Epub 2005 Apr 5.PMID: 15811928 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans.

Basu R, Singh R, Basu A, Johnson CM, Rizza RA.

Diabetes. 2006 Mar;55(3):667-74.PMID: 16505229 [PubMed - indexed for MEDLINE]Related articlesFree article

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

Stimson RH, Andersson J, Andrew R, Redhead DN, Karpe F, Hayes PC, Olsson T, Walker BR.

Diabetes. 2009 Jan;58(1):46-53. Epub 2008 Oct 13.PMID: 18852329 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss.

Purnell JQ, Kahn SE, Samuels MH, Brandon D, Loriaux DL, Brunzell JD.

Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E351-7. Epub 2008 Dec 2.PMID: 19050176 [PubMed - indexed for MEDLINE]Related articles

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

Stewart PM, Toogood AA, Tomlinson JW.

Horm Res. 2001;56 Suppl 1:1-6. Review.PMID: 11786677 [PubMed - indexed for MEDLINE]Related articles

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.PMID: 14557475 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

Rask E, Walker BR, Söderberg S, Livingstone DE, Eliasson M, Johnson O, Andrew R, Olsson T.

J Clin Endocrinol Metab. 2002 Jul;87(7):3330-6.PMID: 12107245 [PubMed - indexed for MEDLINE]Related articlesFree article

1,25-dihydroxyvitamin D3 modulation of adipocyte glucocorticoid function.

Morris KL, Zemel MB.

Obes Res. 2005 Apr;13(4):670-7.PMID: 15897475 [PubMed - indexed for MEDLINE]Related articles

11Beta-HSD type 1 expression in human adipose tissue: impact of gender, obesity, and fat localization.

Paulsen SK, Pedersen SB, Fisker S, Richelsen B.

Obesity (Silver Spring). 2007 Aug;15(8):1954-60.PMID: 17712112 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific dysregulation of cortisol metabolism in human obesity.

Rask E, Olsson T, Söderberg S, Andrew R, Livingstone DE, Johnson O, Walker BR.

J Clin Endocrinol Metab. 2001 Mar;86(3):1418-21.PMID: 11238541 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 enzyme in subcutaneous and visceral adipose tissue of prepubertal children.

Mericq V, Medina P, Bouwman C, Johnson MC, Godoy J, López T, Iñiguez G.

Horm Res. 2009;71(2):89-93. Epub 2009 Jan 8.PMID: 19129713 [PubMed - indexed for MEDLINE]Related articles

11beta-Hydroxysteroid dehydrogenase type 1-driven cortisone reactivation regulates plasminogen activator inhibitor type 1 in adipose tissue of obese women.

Ayachi SE, Paulmyer-Lacroix O, Verdier M, Alessi MC, Dutour A, Grino M.

J Thromb Haemost. 2006 Mar;4(3):621-7.PMID: 16460444 [PubMed - indexed for MEDLINE]Related articles

Expression of the mRNA coding for 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study.

Paulmyer-Lacroix O, Boullu S, Oliver C, Alessi MC, Grino M.

J Clin Endocrinol Metab. 2002 Jun;87(6):2701-5.PMID: 12050237 [PubMed - indexed for MEDLINE]Related articlesFree article

The splanchnic removal of cortisol from plasma of anaesthetized adult guinea-pigs.

Manin M, Tournaire C, Delost P.

J Endocrinol. 1983 Feb;96(2):273-80.PMID: 6827208 [PubMed - indexed for MEDLINE]Related articles

Portal and peripheral cortisol levels in obese humans.

Aldhahi W, Mun E, Goldfine AB.

Diabetologia. 2004 May;47(5):833-6. Epub 2004 Apr 17.PMID: 15095041 [PubMed - indexed for MEDLINE]Related articles

Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity.

Stewart PM, Boulton A, Kumar S, Clark PM, Shackleton CH.

J Clin Endocrinol Metab. 1999 Mar;84(3):1022-7.PMID: 10084590 [PubMed - indexed for MEDLINE]Related articlesFree article