PubMed

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice.

Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, Vonderfecht S, Hecht R, Li YS, Lindberg RA, Chen JL, Jung DY, Zhang Z, Ko HJ, Kim JK, Véniant MM.

Diabetes. 2009 Jan;58(1):250-9. Epub 2008 Oct 7.PMID: 18840786 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor 21 corrects obesity in mice.

Coskun T, Bina HA, Schneider MA, Dunbar JD, Hu CC, Chen Y, Moller DE, Kharitonenkov A.

Endocrinology. 2008 Dec;149(12):6018-27. Epub 2008 Aug 7.PMID: 18687777 [PubMed - indexed for MEDLINE]Related articles

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.PMID: 17322064 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice.

den Boer MA, Voshol PJ, Schröder-van der Elst JP, Korsheninnikova E, Ouwens DM, Kuipers F, Havekes LM, Romijn JA.

Endocrinology. 2006 Oct;147(10):4553-8. Epub 2006 May 18.PMID: 16709607 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese mice.

Yu XX, Murray SF, Watts L, Booten SL, Tokorcheck J, Monia BP, Bhanot S.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E436-45. Epub 2008 Jun 3.PMID: 18523126 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice.

Srivastava RA, Jahagirdar R, Azhar S, Sharma S, Bisgaier CL.

Mol Cell Biochem. 2006 Apr;285(1-2):35-50. Epub 2006 Feb 14.PMID: 16477380 [PubMed - indexed for MEDLINE]Related articles

Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.

Sutton GM, Trevaskis JL, Hulver MW, McMillan RP, Markward NJ, Babin MJ, Meyer EA, Butler AA.

Endocrinology. 2006 May;147(5):2183-96. Epub 2006 Feb 9.PMID: 16469808 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice.

Newberry EP, Xie Y, Kennedy SM, Luo J, Davidson NO.

Hepatology. 2006 Nov;44(5):1191-205.PMID: 17058218 [PubMed - indexed for MEDLINE]Related articles

Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

Wilkes JJ, Lloyd DJ, Gekakis N.

Diabetes. 2009 May;58(5):1133-43. Epub 2009 Feb 10.PMID: 19208906 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.

Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK.

Diabetes. 2009 Mar;58(3):590-9. Epub 2008 Dec 15.PMID: 19074988 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal and postnatal pathways to obesity: different underlying mechanisms, different metabolic outcomes.

Thompson NM, Norman AM, Donkin SS, Shankar RR, Vickers MH, Miles JL, Breier BH.

Endocrinology. 2007 May;148(5):2345-54. Epub 2007 Feb 1.PMID: 17272392 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum fibroblast growth factor 21 is associated with adverse lipid profiles and gamma-glutamyltransferase but not insulin sensitivity in Chinese subjects.

Li H, Bao Y, Xu A, Pan X, Lu J, Wu H, Lu H, Xiang K, Jia W.

J Clin Endocrinol Metab. 2009 Jun;94(6):2151-6. Epub 2009 Mar 24.PMID: 19318452 [PubMed - indexed for MEDLINE]Related articles

Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.

Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC.

PLoS One. 2009;4(3):e4937. Epub 2009 Mar 19.PMID: 19295913 [PubMed - indexed for MEDLINE]Related articlesFree article

Butyrate improves insulin sensitivity and increases energy expenditure in mice.

Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J.

Diabetes. 2009 Jul;58(7):1509-17. Epub 2009 Apr 14.PMID: 19366864 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice.

Vieira VJ, Valentine RJ, Wilund KR, Antao N, Baynard T, Woods JA.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1164-71. Epub 2009 Mar 10.PMID: 19276393 [PubMed - indexed for MEDLINE]Related articles

A novel aminosterol reverses diabetes and fatty liver disease in obese mice.

Takahashi N, Qi Y, Patel HR, Ahima RS.

J Hepatol. 2004 Sep;41(3):391-8.PMID: 15336441 [PubMed - indexed for MEDLINE]Related articles

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.

Diabetes. 2008 Aug;57(8):1999-2011. Epub 2008 May 5.PMID: 18458147 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.

Grefhorst A, van Dijk TH, Hammer A, van der Sluijs FH, Havinga R, Havekes LM, Romijn JA, Groot PH, Reijngoud DJ, Kuipers F.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E829-38. Epub 2005 Jun 7.PMID: 15941783 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.

Nogueiras R, Veyrat-Durebex C, Suchanek PM, Klein M, Tschöp J, Caldwell C, Woods SC, Wittmann G, Watanabe M, Liposits Z, Fekete C, Reizes O, Rohner-Jeanrenaud F, Tschöp MH.

Diabetes. 2008 Nov;57(11):2977-91. Epub 2008 Aug 20.PMID: 18716045 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression.

Yu XX, Pandey SK, Booten SL, Murray SF, Monia BP, Bhanot S.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E530-9. Epub 2008 Jan 15.PMID: 18198353 [PubMed - indexed for MEDLINE]Related articlesFree article