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    Results: 1 to 20 of 221

    1.

    Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes.

    Xie Z, Zhang J, Wu J, Viollet B, Zou MH.

    Diabetes. 2008 Dec;57(12):3222-30. Epub 2008 Oct 3.PMID: 18835932 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I.

    Wang S, Xu J, Song P, Viollet B, Zou MH.

    Diabetes. 2009 Aug;58(8):1893-901. Epub 2009 Jun 15.PMID: 19528375 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Stimulation of glucose transport in response to activation of distinct AMPK signaling pathways.

    Jing M, Cheruvu VK, Ismail-Beigi F.

    Am J Physiol Cell Physiol. 2008 Nov;295(5):C1071-82. Epub 2008 Aug 13.PMID: 18701654 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin.

    Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, Coselli JS, Chen L, Wang XL, Zhang Y, Shen YH.

    Diabetes. 2009 Oct;58(10):2246-57. Epub 2009 Jul 10.PMID: 19592618 [PubMed - indexed for MEDLINE]Related articles

    5.

    Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.

    Hattori Y, Suzuki K, Hattori S, Kasai K.

    Hypertension. 2006 Jun;47(6):1183-8. Epub 2006 Apr 24.PMID: 16636195 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    AMP-activated protein kinase activation by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression.

    Kim JE, Kim YW, Lee IK, Kim JY, Kang YJ, Park SY.

    J Pharmacol Sci. 2008 Mar;106(3):394-403.PMID: 18360094 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species.

    Zou MH, Kirkpatrick SS, Davis BJ, Nelson JS, Wiles WG 4th, Schlattner U, Neumann D, Brownlee M, Freeman MB, Goldman MH.

    J Biol Chem. 2004 Oct 15;279(42):43940-51. Epub 2004 Jul 19.PMID: 15265871 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    5-aminoimidazole-4-carboxamide riboside (AICAR) enhances GLUT2-dependent jejunal glucose transport: a possible role for AMPK.

    Walker J, Jijon HB, Diaz H, Salehi P, Churchill T, Madsen KL.

    Biochem J. 2005 Jan 15;385(Pt 2):485-91.PMID: 15367103 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells.

    Morrow VA, Foufelle F, Connell JM, Petrie JR, Gould GW, Salt IP.

    J Biol Chem. 2003 Aug 22;278(34):31629-39. Epub 2003 Jun 4.PMID: 12791703 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.

    Chen Z, Peng IC, Sun W, Su MI, Hsu PH, Fu Y, Zhu Y, DeFea K, Pan S, Tsai MD, Shyy JY.

    Circ Res. 2009 Feb 27;104(4):496-505. Epub 2009 Jan 8.PMID: 19131647 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Activation of AMP kinase alpha1 subunit induces aortic vasorelaxation in mice.

    Goirand F, Solar M, Athea Y, Viollet B, Mateo P, Fortin D, Leclerc J, Hoerter J, Ventura-Clapier R, Garnier A.

    J Physiol. 2007 Jun 15;581(Pt 3):1163-71. Epub 2007 Apr 19.PMID: 17446219 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells.

    Dagher Z, Ruderman N, Tornheim K, Ido Y.

    Circ Res. 2001 Jun 22;88(12):1276-82.PMID: 11420304 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.

    Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T.

    J Biol Chem. 2008 Dec 5;283(49):33902-10. Epub 2008 Sep 17.PMID: 18801732 [PubMed - indexed for MEDLINE]Related articles

    14.

    Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.

    Cai Y, Martens GA, Hinke SA, Heimberg H, Pipeleers D, Van de Casteele M.

    Free Radic Biol Med. 2007 Jan 1;42(1):64-78. Epub 2006 Sep 27.PMID: 17157194 [PubMed - indexed for MEDLINE]Related articles

    15.

    Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation.

    Ido Y, Carling D, Ruderman N.

    Diabetes. 2002 Jan;51(1):159-67.PMID: 11756336 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

    Davis BJ, Xie Z, Viollet B, Zou MH.

    Diabetes. 2006 Feb;55(2):496-505.PMID: 16443786 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages.

    Jhun BS, Jin Q, Oh YT, Kim SS, Kong Y, Cho YH, Ha J, Baik HH, Kang I.

    Biochem Biophys Res Commun. 2004 May 28;318(2):372-80.PMID: 15120611 [PubMed - indexed for MEDLINE]Related articles

    18.

    Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes.

    Sakoda H, Ogihara T, Anai M, Fujishiro M, Ono H, Onishi Y, Katagiri H, Abe M, Fukushima Y, Shojima N, Inukai K, Kikuchi M, Oka Y, Asano T.

    Am J Physiol Endocrinol Metab. 2002 Jun;282(6):E1239-44.PMID: 12006353 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.

    Glund S, Treebak JT, Long YC, Barres R, Viollet B, Wojtaszewski JF, Zierath JR.

    Endocrinology. 2009 Feb;150(2):600-6. Epub 2008 Sep 25.PMID: 18818284 [PubMed - indexed for MEDLINE]Related articles

    20.

    AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.

    Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR 3rd, Young LH.

    Circ Res. 2005 Oct 28;97(9):872-9. Epub 2005 Sep 22.PMID: 16179588 [PubMed - indexed for MEDLINE]Related articlesFree article

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