PubMed

Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.

Singh VP, Le B, Khode R, Baker KM, Kumar R.

Diabetes. 2008 Dec;57(12):3297-306. Epub 2008 Oct 1. Erratum in: Diabetes. 2009 Mar;58(3):770. PMID: 18829990 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production.

Singh VP, Baker KM, Kumar R.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1675-84. Epub 2008 Feb 22.PMID: 18296558 [PubMed - indexed for MEDLINE]Related articlesFree article

High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes.

Singh VP, Le B, Bhat VB, Baker KM, Kumar R.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H939-48. Epub 2007 May 4.PMID: 17483239 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?

Athyros VG, Mikhailidis DP, Kakafika AI, Tziomalos K, Karagiannis A.

Expert Opin Pharmacother. 2007 Apr;8(5):529-35. Review.PMID: 17376010 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular oxidative stress is reduced by an ACE inhibitor in a rat model of streptozotocin-induced diabetes.

Fiordaliso F, Cuccovillo I, Bianchi R, Bai A, Doni M, Salio M, De Angelis N, Ghezzi P, Latini R, Masson S.

Life Sci. 2006 Jun 6;79(2):121-9. Epub 2006 Jan 30.PMID: 16445948 [PubMed - indexed for MEDLINE]Related articles

Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro.

Malhotra R, Sadoshima J, Brosius FC 3rd, Izumo S.

Circ Res. 1999 Jul 23;85(2):137-46.PMID: 10417395 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.

Kojima M, Shiojima I, Yamazaki T, Komuro I, Zou Z, Wang Y, Mizuno T, Ueki K, Tobe K, Kadowaki T, et al.

Circulation. 1994 May;89(5):2204-11.PMID: 8181146 [PubMed - indexed for MEDLINE]Related articles

Renin-angiotensin system and myocardial collagen matrix: modulation of cardiac fibroblast function by angiotensin II type 1 receptor antagonism.

Brilla CG, Scheer C, Rupp H.

J Hypertens Suppl. 1997 Dec;15(6):S13-9.PMID: 9493122 [PubMed - indexed for MEDLINE]Related articles

Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.

van Kesteren CA, Saris JJ, Dekkers DH, Lamers JM, Saxena PR, Schalekamp MA, Danser AH.

Cardiovasc Res. 1999 Jul;43(1):148-56.PMID: 10536699 [PubMed - indexed for MEDLINE]Related articlesFree article

The renin-angiotensin system and experimental heart failure.

Wollert KC, Drexler H.

Cardiovasc Res. 1999 Sep;43(4):838-49. Review.PMID: 10615411 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of potassium currents by angiotensin and oxidative stress in cardiac cells from the diabetic rat.

Shimoni Y, Hunt D, Chuang M, Chen KY, Kargacin G, Severson DL.

J Physiol. 2005 Aug 15;567(Pt 1):177-90. Epub 2005 Jun 9.PMID: 15946965 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of beta-adrenergic and renin-angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats.

Fiordaliso F, De Angelis N, Bai A, Cuccovillo I, Salio M, Serra DM, Bianchi R, Razzetti R, Latini R, Masson S.

Life Sci. 2007 Sep 1;81(12):951-9. Epub 2007 Jun 21.PMID: 17825849 [PubMed - indexed for MEDLINE]Related articles

Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats.

Takeda Y, Zhu A, Yoneda T, Usukura M, Takata H, Yamagishi M.

Am J Hypertens. 2007 Oct;20(10):1119-24.PMID: 17903697 [PubMed - indexed for MEDLINE]Related articles

[Pathophysiological and clinical implications of AT(1) and AT(2) angiotensin II receptors in metabolic disorders: hypercholesterolaemia and diabetes]

Strawn WB.

Drugs. 2002;62 Spec No 1:31-41. Review. French. PMID: 12036387 [PubMed - indexed for MEDLINE]Related articles

High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system.

Ko SH, Hong OK, Kim JW, Ahn YB, Song KH, Cha BY, Son HY, Kim MJ, Jeong IK, Yoon KH.

J Cell Biochem. 2006 May 15;98(2):343-55.PMID: 16408293 [PubMed - indexed for MEDLINE]Related articles

Long-term angiotensin II blockade may improve not only hyperglycemia but also age-associated cardiac fibrosis.

Jin D, Takai S, Sugiyama T, Hayashi T, Fukumoto M, Oku H, Kitaura Y, Ikeda T, Miyazaki M.

J Pharmacol Sci. 2009 Feb;109(2):275-84. Epub 2009 Feb 7.PMID: 19202318 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of Angiotensin II Type 1 receptor blocker on cardiac angiotensin-converting enzyme and chymase-like activities, and cardiac fibrosis in cardiomyopathic hamsters.

Shimizu M, Tanaka R, Uchida M, Orito K, Shimamura S, Yamane Y.

J Vet Med Sci. 2006 Mar;68(3):227-33.PMID: 16598165 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential autocrine modulation of atrial and ventricular potassium currents and of oxidative stress in diabetic rats.

Shimoni Y, Hunt D, Chen K, Emmett T, Kargacin G.

Am J Physiol Heart Circ Physiol. 2006 May;290(5):H1879-88. Epub 2005 Dec 9.PMID: 16339825 [PubMed - indexed for MEDLINE]Related articlesFree article

Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.

Zimpelmann J, Kumar D, Levine DZ, Wehbi G, Imig JD, Navar LG, Burns KD.

Kidney Int. 2000 Dec;58(6):2320-30.PMID: 11115066 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats.

Paull JR, Widdop RE.

J Hypertens. 2001 Aug;19(8):1393-402.PMID: 11518847 [PubMed - indexed for MEDLINE]Related articles