PubMed

Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients.

Kallergi G, Agelaki S, Kalykaki A, Stournaras C, Mavroudis D, Georgoulias V.

Breast Cancer Res. 2008;10(5):R80. Epub 2008 Sep 29.PMID: 18822183 [PubMed - indexed for MEDLINE]Related articlesFree article

Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.

Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, Sato N.

Cancer Res. 2005 Dec 1;65(23):11018-25.PMID: 16322251 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cells.

Thomas CY, Chouinard M, Cox M, Parsons S, Stallings-Mann M, Garcia R, Jove R, Wharen R.

Int J Cancer. 2003 Mar 10;104(1):19-27.PMID: 12532415 [PubMed - indexed for MEDLINE]Related articles

Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells.

Kallergi G, Mavroudis D, Georgoulias V, Stournaras C.

Mol Med. 2007 Jan-Feb;13(1-2):79-88.PMID: 17515959 [PubMed - indexed for MEDLINE]Related articlesFree article

Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.

Gupta AK, McKenna WG, Weber CN, Feldman MD, Goldsmith JD, Mick R, Machtay M, Rosenthal DI, Bakanauskas VJ, Cerniglia GJ, Bernhard EJ, Weber RS, Muschel RJ.

Clin Cancer Res. 2002 Mar;8(3):885-92.PMID: 11895923 [PubMed - indexed for MEDLINE]Related articlesFree article

Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells.

Sengupta S, Schiff R, Katzenellenbogen BS.

Breast Cancer Res Treat. 2009 Sep;117(2):243-51. Epub 2008 Sep 19.PMID: 18807177 [PubMed - indexed for MEDLINE]Related articlesFree article

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

Raufman JP, Shant J, Guo CY, Roy S, Cheng K.

J Cell Physiol. 2008 May;215(2):538-49.PMID: 18064605 [PubMed - indexed for MEDLINE]Related articles

Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.

She QB, Solit D, Basso A, Moasser MM.

Clin Cancer Res. 2003 Oct 1;9(12):4340-6.PMID: 14555504 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors.

Chan CT, Metz MZ, Kane SE.

Breast Cancer Res Treat. 2005 May;91(2):187-201.PMID: 15868447 [PubMed - indexed for MEDLINE]Related articles

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells.

Marty B, Maire V, Gravier E, Rigaill G, Vincent-Salomon A, Kappler M, Lebigot I, Djelti F, Tourdès A, Gestraud P, Hupé P, Barillot E, Cruzalegui F, Tucker GC, Stern MH, Thiery JP, Hickman JA, Dubois T.

Breast Cancer Res. 2008;10(6):R101. Epub 2008 Dec 3.PMID: 19055754 [PubMed - indexed for MEDLINE]Related articlesFree article

Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.

Pan MH, Lin CC, Lin JK, Chen WJ.

J Agric Food Chem. 2007 Jun 27;55(13):5030-7. Epub 2007 Jun 1.PMID: 17539658 [PubMed - indexed for MEDLINE]Related articles

Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients.

Asgeirsson KS, Agrawal A, Allen C, Hitch A, Ellis IO, Chapman C, Cheung KL, Robertson JF.

Breast Cancer Res. 2007;9(6):R75.PMID: 17976236 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors.

Frogne T, Laenkholm AV, Lyng MB, Henriksen KL, Lykkesfeldt AE.

Breast Cancer Res. 2009;11(1):R11. Epub 2009 Feb 24.PMID: 19239686 [PubMed - indexed for MEDLINE]Related articlesFree article

Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?

Hlobilkova A, Ehrmann J, Sedlakova E, Krejci V, Knizetova P, Fiuraskova M, Kala M, Kalita O, Kolar Z.

Neoplasma. 2007;54(4):334-41.PMID: 17822324 [PubMed - indexed for MEDLINE]Related articles

Expression patterns and predictive value of phosphorylated AKT in early-stage breast cancer.

Andre F, Nahta R, Conforti R, Boulet T, Aziz M, Yuan LX, Meslin F, Spielmann M, Tomasic G, Pusztai L, Hortobagyi GN, Michiels S, Delaloge S, Esteva FJ.

Ann Oncol. 2008 Feb;19(2):315-20. Epub 2007 Sep 5.PMID: 17804473 [PubMed - indexed for MEDLINE]Related articlesFree article

Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway.

Way TD, Kao MC, Lin JK.

J Biol Chem. 2004 Feb 6;279(6):4479-89. Epub 2003 Nov 5.PMID: 14602723 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type I insulin-like growth factor receptor and epidermal growth factor receptor.

Hu YP, Patil SB, Panasiewicz M, Li W, Hauser J, Humphrey LE, Brattain MG.

Cancer Res. 2008 Oct 1;68(19):8004-13.PMID: 18829558 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells.

Zhou C, Qiu L, Sun Y, Healey S, Wanebo H, Kouttab N, Di W, Yan B, Wan Y.

Int J Oncol. 2006 Jul;29(1):269-78.PMID: 16773209 [PubMed - indexed for MEDLINE]Related articles

Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.

Liu X, Carlisle DL, Swick MC, Gaither-Davis A, Grandis JR, Siegfried JM.

Exp Cell Res. 2007 Apr 15;313(7):1361-72. Epub 2007 Feb 3.PMID: 17349623 [PubMed - indexed for MEDLINE]Related articles

Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JM, Robertson JF, Ellis IO, Nicholson RI.

Breast Cancer Res. 2007;9(4):R50.PMID: 17686159 [PubMed - indexed for MEDLINE]Related articlesFree article