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    Results: 1 to 20 of 166

    1.

    Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle.

    Nieto-Vazquez I, Fernández-Veledo S, de Alvaro C, Lorenzo M.

    Diabetes. 2008 Dec;57(12):3211-21. Epub 2008 Sep 16.PMID: 18796617 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance.

    Nieto-Vazquez I, Fernández-Veledo S, de Alvaro C, Rondinone CM, Valverde AM, Lorenzo M.

    Diabetes. 2007 Feb;56(2):404-13.PMID: 17259385 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    c-Jun N-terminal kinase 1/2 activation by tumor necrosis factor-alpha induces insulin resistance in human visceral but not subcutaneous adipocytes: reversal by liver X receptor agonists.

    Fernández-Veledo S, Vila-Bedmar R, Nieto-Vazquez I, Lorenzo M.

    J Clin Endocrinol Metab. 2009 Sep;94(9):3583-93. Epub 2009 Jun 30.PMID: 19567513 [PubMed - indexed for MEDLINE]Related articles

    4.

    siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.

    Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A.

    Diabetes. 2008 Aug;57(8):2066-73. Epub 2008 Apr 28.PMID: 18443205 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.

    Jager J, Grémeaux T, Cormont M, Le Marchand-Brustel Y, Tanti JF.

    Endocrinology. 2007 Jan;148(1):241-51. Epub 2006 Oct 12.PMID: 17038556 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.

    Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB.

    J Biol Chem. 2000 Jun 16;275(24):18318-26.PMID: 10751417 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells.

    Weigert C, Hennige AM, Lehmann R, Brodbeck K, Baumgartner F, Schaüble M, Häring HU, Schleicher ED.

    J Biol Chem. 2006 Mar 17;281(11):7060-7. Epub 2006 Jan 17.PMID: 16418171 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

    Bouzakri K, Zierath JR.

    J Biol Chem. 2007 Mar 16;282(11):7783-9. Epub 2007 Jan 16.PMID: 17227768 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

    D'Alessandris C, Lauro R, Presta I, Sesti G.

    Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

    10.

    Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.

    Storz P, Döppler H, Wernig A, Pfizenmaier K, Müller G.

    Eur J Biochem. 1999 Nov;266(1):17-25.PMID: 10542046 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

    Thong FS, Bilan PJ, Klip A.

    Diabetes. 2007 Feb;56(2):414-23.PMID: 17259386 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells.

    Sweeney G, Keen J, Somwar R, Konrad D, Garg R, Klip A.

    Endocrinology. 2001 Nov;142(11):4806-12.PMID: 11606447 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells.

    JeBailey L, Wanono O, Niu W, Roessler J, Rudich A, Klip A.

    Diabetes. 2007 Feb;56(2):394-403.PMID: 17259384 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Contractile C2C12 myotube model for studying exercise-inducible responses in skeletal muscle.

    Nedachi T, Fujita H, Kanzaki M.

    Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1191-204. Epub 2008 Sep 9.PMID: 18780777 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Development of a novel GLUT4 translocation assay for identifying potential novel therapeutic targets for insulin sensitization.

    Liu F, Dallas-Yang Q, Castriota G, Fischer P, Santini F, Ferrer M, Li J, Akiyama TE, Berger JP, Zhang BB, Jiang G.

    Biochem J. 2009 Mar 1;418(2):413-20.PMID: 19035854 [PubMed - indexed for MEDLINE]Related articles

    16.

    Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

    Cartee GD, Wojtaszewski JF.

    Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.PMID: 17510697 [PubMed - indexed for MEDLINE]Related articles

    17.

    Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.

    Huang C, Thirone AC, Huang X, Klip A.

    J Biol Chem. 2005 May 13;280(19):19426-35. Epub 2005 Mar 11.PMID: 15764603 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

    Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS.

    J Biol Chem. 2008 Oct 10;283(41):27653-67. Epub 2008 Jul 31.PMID: 18669636 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Liver X receptor agonists ameliorate TNFalpha-induced insulin resistance in murine brown adipocytes by downregulating protein tyrosine phosphatase-1B gene expression.

    Fernández-Veledo S, Nieto-Vazquez I, Rondinone CM, Lorenzo M.

    Diabetologia. 2006 Dec;49(12):3038-48. Epub 2006 Oct 27.PMID: 17072583 [PubMed - indexed for MEDLINE]Related articles

    20.

    ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells.

    Izawa Y, Yoshizumi M, Fujita Y, Ali N, Kanematsu Y, Ishizawa K, Tsuchiya K, Obata T, Ebina Y, Tomita S, Tamaki T.

    Exp Cell Res. 2005 Aug 15;308(2):291-9.PMID: 15921682 [PubMed - indexed for MEDLINE]Related articles

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