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    Results: 1 to 20 of 175

    1.

    Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.

    Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV.

    Diabetes. 2008 Dec;57(12):3273-80. Epub 2008 Sep 5.PMID: 18776136 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.

    Martinez X, Kreuwel HT, Redmond WL, Trenney R, Hunter K, Rosen H, Sarvetnick N, Wicker LS, Sherman LA.

    J Immunol. 2005 Aug 1;175(3):1677-85.PMID: 16034108 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

    Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

    J Immunol. 2004 Jan 15;172(2):871-9.PMID: 14707058 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice.

    Silveira PA, Chapman HD, Stolp J, Johnson E, Cox SL, Hunter K, Wicker LS, Serreze DV.

    J Immunol. 2006 Nov 15;177(10):7033-41.PMID: 17082619 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors.

    Christianson SW, Shultz LD, Leiter EH.

    Diabetes. 1993 Jan;42(1):44-55.PMID: 8093606 [PubMed - indexed for MEDLINE]Related articles

    6.

    Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.

    Serreze DV, Choisy-Rossi CM, Grier AE, Holl TM, Chapman HD, Gahagan JR, Osborne MA, Zhang W, King BL, Brown A, Roopenian D, Marron MP.

    J Immunol. 2008 Mar 1;180(5):3250-9.PMID: 18292549 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice.

    Sgouroudis E, Albanese A, Piccirillo CA.

    J Immunol. 2008 Nov 1;181(9):6283-92.PMID: 18941219 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non-pathogenic regulatory cells following FoxP3 transduction.

    Peng J, Dicker B, Du W, Tang F, Nguyen P, Geiger T, Wong FS, Wen L.

    J Autoimmun. 2007 Jun;28(4):188-200. Epub 2007 Apr 6.PMID: 17412560 [PubMed - indexed for MEDLINE]Related articles

    9.

    Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice.

    Verdaguer J, Schmidt D, Amrani A, Anderson B, Averill N, Santamaria P.

    J Exp Med. 1997 Nov 17;186(10):1663-76.PMID: 9362527 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    A 20-Mb region of chromosome 4 controls TNF-alpha-mediated CD8+ T cell aggression toward beta cells in type 1 diabetes.

    Chamberlain G, Wållberg M, Rainbow D, Hunter K, Wicker LS, Green EA.

    J Immunol. 2006 Oct 15;177(8):5105-14.PMID: 17015694 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Perturbed homeostasis of peripheral T cells elicits decreased susceptibility to anti-CD3-induced apoptosis in prediabetic nonobese diabetic mice.

    Yang W, Hussain S, Mi QS, Santamaria P, Delovitch TL.

    J Immunol. 2004 Oct 1;173(7):4407-16.PMID: 15383571 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.

    Anderson B, Park BJ, Verdaguer J, Amrani A, Santamaria P.

    Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9311-6.PMID: 10430939 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Dysregulated B7-1 and B7-2 expression on nonobese diabetic mouse B cells is associated with increased T cell costimulation and the development of insulitis.

    Hussain S, Delovitch TL.

    J Immunol. 2005 Jan 15;174(2):680-7.PMID: 15634886 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice.

    Kanagawa O, Shimizu J, Vaupel BA.

    J Immunol. 2000 May 15;164(10):5466-73.PMID: 10799914 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Increased nonobese diabetic Th1:Th2 (IFN-gamma:IL-4) ratio is CD4+ T cell intrinsic and independent of APC genetic background.

    Koarada S, Wu Y, Olshansky G, Ridgway WM.

    J Immunol. 2002 Dec 1;169(11):6580-7.PMID: 12444170 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.

    Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

    J Immunol. 2000 Apr 1;164(7):3913-8.PMID: 10725754 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice.

    Mora C, Wong FS, Chang CH, Flavell RA.

    J Immunol. 1999 Apr 15;162(8):4576-88.PMID: 10201997 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development.

    Gregori S, Giarratana N, Smiroldo S, Adorini L.

    J Immunol. 2003 Oct 15;171(8):4040-7.PMID: 14530324 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.

    McAleer MA, Reifsnyder P, Palmer SM, Prochazka M, Love JM, Copeman JB, Powell EE, Rodrigues NR, Prins JB, Serreze DV, et al.

    Diabetes. 1995 Oct;44(10):1186-95.PMID: 7556956 [PubMed - indexed for MEDLINE]Related articles

    20.

    Increased entry into the IFN-gamma effector pathway by CD4+ T cells selected by I-Ag7 on a nonobese diabetic versus C57BL/6 genetic background.

    Koarada S, Wu Y, Ridgway WM.

    J Immunol. 2001 Aug 1;167(3):1693-702.PMID: 11466393 [PubMed - indexed for MEDLINE]Related articlesFree article

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