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    Results: 1 to 20 of 100

    1.

    Isolated populations and complex disease gene identification.

    Kristiansson K, Naukkarinen J, Peltonen L.

    Genome Biol. 2008;9(8):109. Epub 2008 Aug 26.

    PMID:
    18771588
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

    Lowe JK, Maller JB, Pe'er I, Neale BM, Salit J, Kenny EE, Shea JL, Burkhardt R, Smith JG, Ji W, Noel M, Foo JN, Blundell ML, Skilling V, Garcia L, Sullivan ML, Lee HE, Labek A, Ferdowsian H, Auerbach SB, Lifton RP, Newton-Cheh C, Breslow JL, Stoffel M, Daly MJ, Altshuler DM, Friedman JM.

    PLoS Genet. 2009 Feb;5(2):e1000365. Epub 2009 Feb 6.

    PMID:
    19197348
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    The Newfoundland population: a unique resource for genetic investigation of complex diseases.

    Rahman P, Jones A, Curtis J, Bartlett S, Peddle L, Fernandez BA, Freimer NB.

    Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R167-72. Epub 2003 Aug 5. Review. Erratum in: Hum Mol Genet. 2004 Jun 15;13(12):1287.

    PMID:
    12915452
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Linkage-disequilibrium mapping of disease genes by reconstruction of ancestral haplotypes in founder populations.

    Service SK, Lang DW, Freimer NB, Sandkuijl LA.

    Am J Hum Genet. 1999 Jun;64(6):1728-38.

    PMID:
    10330361
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    The value of some Corsican sub-populations for genetic association studies.

    Latini V, Sole G, Varesi L, Vona G, Ristaldi MS.

    BMC Med Genet. 2008 Jul 28;9:73.

    PMID:
    18662385
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Are common disease susceptibility alleles the same in outbred and founder populations?

    Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C.

    Eur J Hum Genet. 2004 Jul;12(7):584-90.

    PMID:
    15100713
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    The genetically isolated populations of Finland and sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes.

    Eaves IA, Merriman TR, Barber RA, Nutland S, Tuomilehto-Wolf E, Tuomilehto J, Cucca F, Todd JA.

    Nat Genet. 2000 Jul;25(3):320-3.

    PMID:
    10888882
    [PubMed - indexed for MEDLINE]
    8.

    Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.

    Kaneva R, Milanova V, Angelicheva D, MacGregor S, Kostov C, Vladimirova R, Aleksiev S, Angelova M, Stoyanova V, Loh A, Hallmayer J, Kalaydjieva L, Jablensky A.

    Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):191-201.

    PMID:
    18444255
    [PubMed - indexed for MEDLINE]
    9.

    Genetic isolates in Corsica (France): linkage disequilibrium extension analysis on the Xq13 region.

    Latini V, Sole G, Doratiotto S, Poddie D, Memmi M, Varesi L, Vona G, Cao A, Ristaldi MS.

    Eur J Hum Genet. 2004 Aug;12(8):613-9.

    PMID:
    15114371
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    The genetics of asthma. Mapping genes for complex traits in founder populations.

    Ober C, Cox NJ.

    Clin Exp Allergy. 1998 Apr;28 Suppl 1:101-5; discussion 108-10. No abstract available.

    PMID:
    9641605
    [PubMed - indexed for MEDLINE]
    11.

    Genetic isolates in ophthalmic diseases.

    Sherwin JC, Hewitt AW, Ruddle JB, Mackey DA.

    Ophthalmic Genet. 2008 Dec;29(4):149-61. Review.

    PMID:
    19005985
    [PubMed - indexed for MEDLINE]
    12.

    Linkage disequilibrium mapping in isolated populations: the example of Finland revisited.

    de la Chapelle A, Wright FA.

    Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12416-23.

    PMID:
    9770501
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    The genome-wide patterns of variation expose significant substructure in a founder population.

    Jakkula E, Rehnström K, Varilo T, Pietiläinen OP, Paunio T, Pedersen NL, deFaire U, Järvelin MR, Saharinen J, Freimer N, Ripatti S, Purcell S, Collins A, Daly MJ, Palotie A, Peltonen L.

    Am J Hum Genet. 2008 Dec;83(6):787-94.

    PMID:
    19061986
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Allelic association: linkage disequilibrium structure and gene mapping.

    Collins A.

    Mol Biotechnol. 2009 Jan;41(1):83-9. Epub 2008 Oct 8. Review.

    PMID:
    18841501
    [PubMed - indexed for MEDLINE]
    15.

    Common genetic variation and human disease.

    Orr N, Chanock S.

    Adv Genet. 2008;62:1-32. Review.

    PMID:
    19010252
    [PubMed - indexed for MEDLINE]
    16.

    Population isolates in South Tyrol and their value for genetic dissection of complex diseases.

    Marroni F, Pichler I, De Grandi A, Volpato CB, Vogl FD, Pinggera GK, Bailey-Wilson JE, Pramstaller PP.

    Ann Hum Genet. 2006 Nov;70(Pt 6):812-21.

    PMID:
    17044856
    [PubMed - indexed for MEDLINE]
    17.

    The value of isolated populations in genetic studies of allergic diseases.

    Laitinen T.

    Curr Opin Allergy Clin Immunol. 2002 Oct;2(5):379-82. Review.

    PMID:
    12582319
    [PubMed - indexed for MEDLINE]
    18.

    Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.

    Bosch E, Laayouni H, Morcillo-Suarez C, Casals F, Moreno-Estrada A, Ferrer-Admetlla A, Gardner M, Rosa A, Navarro A, Comas D, Graffelman J, Calafell F, Bertranpetit J.

    BMC Genomics. 2009 Jul 28;10:338.

    PMID:
    19638193
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database.

    Karayiorgou M, Torrington M, Abecasis GR, Pretorius H, Robertson B, Kaliski S, Lay S, Sobin C, Möller N, Lundy SL, Blundell ML, Gogos JA, Roos JL.

    Am J Med Genet B Neuropsychiatr Genet. 2004 Jan 1;124B(1):20-8.

    PMID:
    14681908
    [PubMed - indexed for MEDLINE]
    20.

    Messages from an isolate: lessons from the Finnish gene pool.

    Peltonen L, Pekkarinen P, Aaltonen J.

    Biol Chem Hoppe Seyler. 1995 Dec;376(12):697-704. Review.

    PMID:
    9072044
    [PubMed - indexed for MEDLINE]

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