PubMed

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role.

Giliberto L, Zhou D, Weldon R, Tamagno E, De Luca P, Tabaton M, D'Adamio L.

Mol Neurodegener. 2008 Sep 2;3:12.PMID: 18764939 [PubMed - in process]Related articlesFree article

JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65.

Scheinfeld MH, Matsuda S, D'Adamio L.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1729-34. Epub 2003 Jan 31.PMID: 12563035 [PubMed - indexed for MEDLINE]Related articlesFree article

The FE65 proteins and Alzheimer's disease.

McLoughlin DM, Miller CC.

J Neurosci Res. 2008 Mar;86(4):744-54. Review.PMID: 17828772 [PubMed - indexed for MEDLINE]Related articles

Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission.

Schrenk-Siemens K, Perez-Alcala S, Richter J, Lacroix E, Rahuel J, Korte M, Müller U, Barde YA, Bibel M.

Stem Cells. 2008 Aug;26(8):2153-63. Epub 2008 Jun 5.PMID: 18535156 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction.

Fombonne J, Rabizadeh S, Banwait S, Mehlen P, Bredesen DE.

Ann Neurol. 2009 Mar;65(3):294-303.PMID: 19334058 [PubMed - indexed for MEDLINE]Related articles

A TAG on to the neurogenic functions of APP.

Ma QH, Bagnard D, Xiao ZC, Dawe GS.

Cell Adh Migr. 2008 Jan;2(1):2-8. Epub 2008 Jan 25. Review.PMID: 19262125 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1.

Yu HT, Chan WW, Chai KH, Lee CW, Chang RC, Yu MS, McLoughlin DM, Miller CC, Lau KF.

J Cell Biochem. 2010 Mar 1;109(4):782-93.PMID: 20091743 [PubMed - in process]Related articles

Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories.

Konietzko U, Goodger ZV, Meyer M, Kohli BM, Bosset J, Lahiri DK, Nitsch RM.

Neurobiol Aging. 2010 Jan;31(1):58-73. Epub 2008 Apr 10.PMID: 18403052 [PubMed - in process]Related articles

Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice.

Lee JW, Lee YK, Ban JO, Ha TY, Yun YP, Han SB, Oh KW, Hong JT.

J Nutr. 2009 Oct;139(10):1987-93. Epub 2009 Aug 5.PMID: 19656855 [PubMed - indexed for MEDLINE]Related articles

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease.

Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ.

J Neurosci. 2008 Nov 26;28(48):12877-86.PMID: 19036982 [PubMed - indexed for MEDLINE]Related articlesFree article

A putative role of the Amyloid Precursor Protein Intracellular Domain (AICD) in transcription.

Słomnicki LP, Leśniak W.

Acta Neurobiol Exp (Wars). 2008;68(2):219-28. Review.PMID: 18511958 [PubMed - indexed for MEDLINE]Related articlesFree article

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. Epub 2009 Mar 7.PMID: 19271231 [PubMed - indexed for MEDLINE]Related articles

A dominant role for FE65 (APBB1) in nuclear signaling.

Yang Z, Cool BH, Martin GM, Hu Q.

J Biol Chem. 2006 Feb 17;281(7):4207-14. Epub 2005 Dec 6.PMID: 16332686 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.

Prinzen C, Trümbach D, Wurst W, Endres K, Postina R, Fahrenholz F.

BMC Genomics. 2009 Feb 5;10:66.PMID: 19196476 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.

Liu Y, Zhang YW, Wang X, Zhang H, You X, Liao FF, Xu H.

J Biol Chem. 2009 May 1;284(18):12145-52. Epub 2009 Mar 10.PMID: 19276086 [PubMed - indexed for MEDLINE]Related articles

Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.

Spencer B, Marr RA, Rockenstein E, Crews L, Adame A, Potkar R, Patrick C, Gage FH, Verma IM, Masliah E.

BMC Neurosci. 2008 Nov 12;9:109.PMID: 19014502 [PubMed - indexed for MEDLINE]Related articlesFree article

The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.

Tamayev R, Zhou D, D'Adamio L.

Mol Neurodegener. 2009 Jul 14;4:28.PMID: 19602287 [PubMed - in process]Related articlesFree article

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.

Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE.

J Biol Chem. 2009 May 1;284(18):11863-72. Epub 2009 Feb 27.PMID: 19251705 [PubMed - indexed for MEDLINE]Related articles

Abeta immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice.

Biscaro B, Lindvall O, Hock C, Ekdahl CT, Nitsch RM.

J Neurosci. 2009 Nov 11;29(45):14108-19.PMID: 19906959 [PubMed - indexed for MEDLINE]Related articles

Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain.

Bürger S, Noack M, Kirazov LP, Kirazov EP, Naydenov CL, Kouznetsova E, Yafai Y, Schliebs R.

Int J Dev Neurosci. 2009 Oct;27(6):517-23. Epub 2009 Jul 7.PMID: 19589380 [PubMed - indexed for MEDLINE]Related articles