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A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development.
Jones KS, Alimov AP, Rilo HL, Jandacek RJ, Woollett LA, Penberthy WT.
Nutr Metab (Lond). 2008 Aug 27;5:23.PMID: 18752667 [PubMed - in process]Related articlesFree article
Analysis of small molecule metabolism in zebrafish.
Ho SY, Pack M, Farber SA.
Methods Enzymol. 2003;364:408-26. Review.PMID: 14631858 [PubMed - indexed for MEDLINE]Related articles
[Pharmacological therapy of obesity]
Pagotto U, Vanuzzo D, Vicennati V, Pasquali R.
G Ital Cardiol (Rome). 2008 Apr;9(4 Suppl 1):83S-93S. Italian. PMID: 18773755 [PubMed - indexed for MEDLINE]Related articles
Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae.
Schlegel A, Stainier DY.
Biochemistry. 2006 Dec 26;45(51):15179-87. Epub 2006 Dec 1.PMID: 17176039 [PubMed - indexed for MEDLINE]Related articles
The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.
Barbosa MT, Soares SM, Novak CM, Sinclair D, Levine JA, Aksoy P, Chini EN.
FASEB J. 2007 Nov;21(13):3629-39. Epub 2007 Jun 21.PMID: 17585054 [PubMed - indexed for MEDLINE]Related articlesFree article
Zebrafish as a model for pancreatic cancer research.
Yee NS, Pack M.
Methods Mol Med. 2005;103:273-98.PMID: 15542913 [PubMed - indexed for MEDLINE]Related articles
Making waves in cancer research: new models in the zebrafish.
Berghmans S, Jette C, Langenau D, Hsu K, Stewart R, Look T, Kanki JP.
Biotechniques. 2005 Aug;39(2):227-37. Review.PMID: 16116796 [PubMed - indexed for MEDLINE]Related articlesFree article
Technology for high-throughput screens: the present and future using zebrafish.
Love DR, Pichler FB, Dodd A, Copp BR, Greenwood DR.
Curr Opin Biotechnol. 2004 Dec;15(6):564-71. Review.PMID: 15560983 [PubMed - indexed for MEDLINE]Related articles
Non-associative learning in larval zebrafish.
Best JD, Berghmans S, Hunt JJ, Clarke SC, Fleming A, Goldsmith P, Roach AG.
Neuropsychopharmacology. 2008 Apr;33(5):1206-15. Epub 2007 Jun 20.PMID: 17581529 [PubMed - indexed for MEDLINE]Related articlesFree article
Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs.
Winter MJ, Redfern WS, Hayfield AJ, Owen SF, Valentin JP, Hutchinson TH.
J Pharmacol Toxicol Methods. 2008 May-Jun;57(3):176-87. Epub 2008 Feb 9.PMID: 18337127 [PubMed - indexed for MEDLINE]Related articles
Small molecule screening in the zebrafish.
Murphey RD, Zon LI.
Methods. 2006 Jul;39(3):255-61.PMID: 16877005 [PubMed - indexed for MEDLINE]Related articles
Zebrafish: An in vivo model for the study of neurological diseases.
Best JD, Alderton WK.
Neuropsychiatr Dis Treat. 2008 Jun;4(3):567-76.PMID: 18830398 [PubMed - in process]Related articlesFree article
Lipid metabolism in zebrafish.
Ho SY, Thorpe JL, Deng Y, Santana E, DeRose RA, Farber SA.
Methods Cell Biol. 2004;76:87-108.PMID: 15602873 [PubMed - indexed for MEDLINE]Related articles
Chemical discovery and global gene expression analysis in zebrafish.
Pichler FB, Laurenson S, Williams LC, Dodd A, Copp BR, Love DR.
Nat Biotechnol. 2003 Aug;21(8):879-83. Review.PMID: 12894204 [PubMed - indexed for MEDLINE]Related articles
Clofibrate and gemfibrozil induce an embryonic malabsorption syndrome in zebrafish.
Raldúa D, André M, Babin PJ.
Toxicol Appl Pharmacol. 2008 May 1;228(3):301-14. Epub 2007 Nov 28.PMID: 18358510 [PubMed - indexed for MEDLINE]Related articles
Validation of the use of zebrafish larvae in visual safety assessment.
Richards FM, Alderton WK, Kimber GM, Liu Z, Strang I, Redfern WS, Valentin JP, Winter MJ, Hutchinson TH.
J Pharmacol Toxicol Methods. 2008 Jul-Aug;58(1):50-8. Epub 2008 May 2.PMID: 18541443 [PubMed - indexed for MEDLINE]Related articles
Modeling human muscle disease in zebrafish.
Guyon JR, Steffen LS, Howell MH, Pusack TJ, Lawrence C, Kunkel LM.
Biochim Biophys Acta. 2007 Feb;1772(2):205-15. Epub 2006 Jul 20. Review.PMID: 16934958 [PubMed - indexed for MEDLINE]Related articles
Zebrafish as a developmental model organism for pediatric research.
Veldman MB, Lin S.
Pediatr Res. 2008 Nov;64(5):470-6. Review.PMID: 18679162 [PubMed - indexed for MEDLINE]Related articles
Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo.
Powell DR.
Obes Rev. 2006 Feb;7(1):89-108.PMID: 16436105 [PubMed - indexed for MEDLINE]Related articles
Expression of mt2 and smt-B upon cadmium exposure and cold shock in zebrafish (Danio rerio).
Wu SM, Zheng YD, Kuo CH.
Comp Biochem Physiol C Toxicol Pharmacol. 2008 Aug;148(2):184-93. Epub 2008 May 19.PMID: 18579444 [PubMed - indexed for MEDLINE]Related articles
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