PubMed

Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress.

Senokuchi T, Liang CP, Seimon TA, Han S, Matsumoto M, Banks AS, Paik JH, DePinho RA, Accili D, Tabas I, Tall AR.

Diabetes. 2008 Nov;57(11):2967-76. Epub 2008 Aug 26.PMID: 18728232 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2008 Apr;57(4):846-59. Epub 2008 Jan 3.PMID: 18174526 [PubMed - indexed for MEDLINE]Related articlesFree article

Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.

Lim WS, Timmins JM, Seimon TA, Sadler A, Kolodgie FD, Virmani R, Tabas I.

Circulation. 2008 Feb 19;117(7):940-51. Epub 2008 Jan 28. Erratum in: Circulation. 2008 Apr 1;117(13):e303. PMID: 18227389 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis.

Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I.

J Cell Biol. 2009 Sep 21;186(6):783-92. Epub 2009 Sep 14.PMID: 19752026 [PubMed - indexed for MEDLINE]Related articles

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR.

Cell Metab. 2006 Apr;3(4):257-66.PMID: 16581003 [PubMed - indexed for MEDLINE]Related articles

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages.

Feng B, Yao PM, Li Y, Devlin CM, Zhang D, Harding HP, Sweeney M, Rong JX, Kuriakose G, Fisher EA, Marks AR, Ron D, Tabas I.

Nat Cell Biol. 2003 Sep;5(9):781-92. Epub 2003 Aug 10.PMID: 12907943 [PubMed - indexed for MEDLINE]Related articles

Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor.

Devries-Seimon T, Li Y, Yao PM, Stone E, Wang Y, Davis RJ, Flavell R, Tabas I.

J Cell Biol. 2005 Oct 10;171(1):61-73. Epub 2005 Oct 3.PMID: 16203857 [PubMed - indexed for MEDLINE]Related articlesFree article

The macrophage at the crossroads of insulin resistance and atherosclerosis.

Liang CP, Han S, Senokuchi T, Tall AR.

Circ Res. 2007 Jun 8;100(11):1546-55. Review.PMID: 17556668 [PubMed - indexed for MEDLINE]Related articlesFree article

Free cholesterol-induced macrophage apoptosis is mediated by inositol-requiring enzyme 1 alpha-regulated activation of Jun N-terminal kinase.

Li F, Guo Y, Sun S, Jiang X, Tang B, Wang Q, Wang L.

Acta Biochim Biophys Sin (Shanghai). 2008 Mar;40(3):226-34.PMID: 18330477 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death.

Oumouna-Benachour K, Hans CP, Suzuki Y, Naura A, Datta R, Belmadani S, Fallon K, Woods C, Boulares AH.

Circulation. 2007 May 8;115(18):2442-50. Epub 2007 Apr 16.PMID: 17438151 [PubMed - indexed for MEDLINE]Related articlesFree article

Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin.

Misra UK, Pizzo SV.

J Leukoc Biol. 2005 Jul;78(1):187-94. Epub 2005 Apr 21.PMID: 15845644 [PubMed - indexed for MEDLINE]Related articlesFree article

Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells.

Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I.

J Leukoc Biol. 2007 Nov;82(5):1040-50. Epub 2007 Jun 18.PMID: 17576822 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP.

Gotoh T, Oyadomari S, Mori K, Mori M.

J Biol Chem. 2002 Apr 5;277(14):12343-50. Epub 2002 Jan 22.PMID: 11805088 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice.

Seimon TA, Wang Y, Han S, Senokuchi T, Schrijvers DM, Kuriakose G, Tall AR, Tabas IA.

J Clin Invest. 2009 Apr;119(4):886-98. doi: 10.1172/JCI37262. Epub 2009 Mar 16.PMID: 19287091 [PubMed - indexed for MEDLINE]Related articlesFree article

Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.

Bao S, Li Y, Lei X, Wohltmann M, Jin W, Bohrer A, Semenkovich CF, Ramanadham S, Tabas I, Turk J.

J Biol Chem. 2007 Sep 14;282(37):27100-14. Epub 2007 Jul 12.PMID: 17627946 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation.

Shkoda A, Ruiz PA, Daniel H, Kim SC, Rogler G, Sartor RB, Haller D.

Gastroenterology. 2007 Jan;132(1):190-207. Epub 2006 Oct 21.PMID: 17241871 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress.

Martinet W, Croons V, Timmermans JP, Herman AG, De Meyer GR.

Br J Pharmacol. 2007 Oct;152(4):493-500. Epub 2007 Aug 13.PMID: 17700714 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice.

Thorp E, Kuriakose G, Shah YM, Gonzalez FJ, Tabas I.

Circulation. 2007 Nov 6;116(19):2182-90. Epub 2007 Oct 22.PMID: 17967777 [PubMed - indexed for MEDLINE]Related articlesFree article

Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance.

Lim JH, Lee HJ, Ho Jung M, Song J.

Cell Signal. 2009 Jan;21(1):169-77. Epub 2008 Oct 12.PMID: 18950706 [PubMed - indexed for MEDLINE]Related articles

IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.

Valverde AM, Fabregat I, Burks DJ, White MF, Benito M.

Hepatology. 2004 Dec;40(6):1285-94.PMID: 15565601 [PubMed - indexed for MEDLINE]Related articles