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Endurance exercise as a countermeasure for aging.

Lanza IR, Short DK, Short KR, Raghavakaimal S, Basu R, Joyner MJ, McConnell JP, Nair KS.

Diabetes. 2008 Nov;57(11):2933-42. Epub 2008 Aug 20.PMID: 18716044 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle mitochondrial changes with aging and exercise.

Lanza IR, Nair KS.

Am J Clin Nutr. 2009 Jan;89(1):467S-71S. Epub 2008 Dec 3. Review.PMID: 19056588 [PubMed - indexed for MEDLINE]Related articles

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity.

Short KR, Vittone JL, Bigelow ML, Proctor DN, Rizza RA, Coenen-Schimke JM, Nair KS.

Diabetes. 2003 Aug;52(8):1888-96.PMID: 12882902 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function.

Chow LS, Greenlund LJ, Asmann YW, Short KR, McCrady SK, Levine JA, Nair KS.

J Appl Physiol. 2007 Mar;102(3):1078-89. Epub 2006 Nov 16.PMID: 17110513 [PubMed - indexed for MEDLINE]Related articlesFree article

Decline in insulin action with age in endurance-trained humans.

Clevenger CM, Parker Jones P, Tanaka H, Seals DR, DeSouza CA.

J Appl Physiol. 2002 Dec;93(6):2105-11. Epub 2002 Aug 30.PMID: 12391128 [PubMed - indexed for MEDLINE]Related articlesFree article

Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function.

Karakelides H, Irving BA, Short KR, O'Brien P, Nair KS.

Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833885 [PubMed - as supplied by publisher]Related articles

Decline in skeletal muscle mitochondrial function with aging in humans.

Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, Nair KS.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5618-23. Epub 2005 Mar 30.PMID: 15800038 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of mitochondrial biogenesis in muscle by endurance exercise.

Irrcher I, Adhihetty PJ, Joseph AM, Ljubicic V, Hood DA.

Sports Med. 2003;33(11):783-93. Review.PMID: 12959619 [PubMed - indexed for MEDLINE]Related articles

Physical inactivity and obesity underlie the insulin resistance of aging.

Amati F, Dubé JJ, Coen PM, Stefanovic-Racic M, Toledo FG, Goodpaster BH.

Diabetes Care. 2009 Aug;32(8):1547-9. Epub 2009 Apr 28.PMID: 19401446 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle metabolism during exercise in young and older untrained and endurance-trained men.

Coggan AR, Abduljalil AM, Swanson SC, Earle MS, Farris JW, Mendenhall LA, Robitaille PM.

J Appl Physiol. 1993 Nov;75(5):2125-33.PMID: 8307869 [PubMed - indexed for MEDLINE]Related articles

Effects of acute and chronic endurance exercise on mitochondrial uncoupling in human skeletal muscle.

Fernström M, Tonkonogi M, Sahlin K.

J Physiol. 2004 Feb 1;554(Pt 3):755-63. Epub 2003 Nov 21.PMID: 14634202 [PubMed - indexed for MEDLINE]Related articlesFree article

Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.

Nair KS, Bigelow ML, Asmann YW, Chow LS, Coenen-Schimke JM, Klaus KA, Guo ZK, Sreekumar R, Irving BA.

Diabetes. 2008 May;57(5):1166-75. Epub 2008 Feb 19. Erratum in: Diabetes. 2009 Mar;58(3):770. PMID: 18285554 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals.

Befroy DE, Petersen KF, Dufour S, Mason GF, Rothman DL, Shulman GI.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16701-6. Epub 2008 Oct 20.PMID: 18936488 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise.

De Filippis E, Alvarez G, Berria R, Cusi K, Everman S, Meyer C, Mandarino LJ.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E607-14. Epub 2008 Jan 8.PMID: 18182465 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging skeletal muscle: response to exercise.

Cartee GD.

Exerc Sport Sci Rev. 1994;22:91-120. Review.PMID: 7925554 [PubMed - indexed for MEDLINE]Related articles

Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults.

Fleischman A, Johnsen S, Systrom DM, Hrovat M, Farrar CT, Frontera W, Fitch K, Thomas BJ, Torriani M, Côté HC, Grinspoon SK.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1666-73. Epub 2007 Feb 6.PMID: 17284576 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging muscle.

Nair KS.

Am J Clin Nutr. 2005 May;81(5):953-63. Review.PMID: 15883415 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status.

Bruce CR, Anderson MJ, Carey AL, Newman DG, Bonen A, Kriketos AD, Cooney GJ, Hawley JA.

J Clin Endocrinol Metab. 2003 Nov;88(11):5444-51.PMID: 14602787 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance with aging: effects of diet and exercise.

Ryan AS.

Sports Med. 2000 Nov;30(5):327-46. Review.PMID: 11103847 [PubMed - indexed for MEDLINE]Related articles

Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity.

Rimbert V, Boirie Y, Bedu M, Hocquette JF, Ritz P, Morio B.

FASEB J. 2004 Apr;18(6):737-9. Epub 2004 Feb 20.PMID: 14977873 [PubMed - indexed for MEDLINE]Related articlesFree article