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The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate.
Lopez-Rios J, Esteve P, Ruiz JM, Bovolenta P.
Neural Dev. 2008 Aug 20;3:19.PMID: 18715500 [PubMed - indexed for MEDLINE]Related articlesFree article
Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.
Bovolenta P, Esteve P, Ruiz JM, Cisneros E, Lopez-Rios J.
J Cell Sci. 2008 Mar 15;121(Pt 6):737-46. Review.PMID: 18322270 [PubMed - indexed for MEDLINE]Related articlesFree article
Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range.
Mii Y, Taira M.
Development. 2009 Dec;136(24):4083-8. Epub 2009 Nov 11.PMID: 19906850 [PubMed - indexed for MEDLINE]Related articles
Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer.
Kawano Y, Diez S, Uysal-Onganer P, Darrington RS, Waxman J, Kypta RM.
Br J Cancer. 2009 Apr 7;100(7):1165-74. Epub 2009 Mar 10.PMID: 19277043 [PubMed - indexed for MEDLINE]Related articles
The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway.
Zilberberg A, Yaniv A, Gazit A.
J Biol Chem. 2004 Apr 23;279(17):17535-42. Epub 2004 Jan 21.PMID: 14739301 [PubMed - indexed for MEDLINE]Related articlesFree article
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.
Chong JM, Uren A, Rubin JS, Speicher DW.
J Biol Chem. 2002 Feb 15;277(7):5134-44. Epub 2001 Dec 10.PMID: 11741940 [PubMed - indexed for MEDLINE]Related articlesFree article
Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
Bhat RA, Stauffer B, Komm BS, Bodine PV.
J Cell Biochem. 2007 Dec 15;102(6):1519-28.PMID: 17471511 [PubMed - indexed for MEDLINE]Related articles
Secreted Frizzled-related proteins: searching for relationships and patterns.
Jones SE, Jomary C.
Bioessays. 2002 Sep;24(9):811-20. Review.PMID: 12210517 [PubMed - indexed for MEDLINE]Related articles
Wnt'er in liver: expression of Wnt and frizzled genes in mouse.
Zeng G, Awan F, Otruba W, Muller P, Apte U, Tan X, Gandhi C, Demetris AJ, Monga SP.
Hepatology. 2007 Jan;45(1):195-204.PMID: 17187422 [PubMed - indexed for MEDLINE]Related articles
Frizzled-10 promotes sensory neuron development in Xenopus embryos.
Garcia-Morales C, Liu CH, Abu-Elmagd M, Hajihosseini MK, Wheeler GN.
Dev Biol. 2009 Nov 1;335(1):143-55. Epub 2009 Aug 28.PMID: 19716814 [PubMed - indexed for MEDLINE]Related articles
Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3.
Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW.
Dev Dyn. 2006 Mar;235(3):681-90.PMID: 16425220 [PubMed - indexed for MEDLINE]Related articlesFree article
Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules.
Scardigli R, Gargioli C, Tosoni D, Borello U, Sampaolesi M, Sciorati C, Cannata S, Clementi E, Brunelli S, Cossu G.
PLoS One. 2008 Jun 18;3(6):e2471.PMID: 18560570 [PubMed - indexed for MEDLINE]Related articlesFree article
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling.
Magdesian MH, Carvalho MM, Mendes FA, Saraiva LM, Juliano MA, Juliano L, Garcia-Abreu J, Ferreira ST.
J Biol Chem. 2008 Apr 4;283(14):9359-68. Epub 2008 Jan 30.PMID: 18234671 [PubMed - indexed for MEDLINE]Related articlesFree article
Roles of secreted frizzled-related proteins in cancer.
Shi Y, He B, You L, Jablons DM.
Acta Pharmacol Sin. 2007 Sep;28(9):1499-504. Review.PMID: 17723183 [PubMed - indexed for MEDLINE]Related articlesFree article
Wnt3a binds to several sFRPs in the nanomolar range.
Wawrzak D, Métioui M, Willems E, Hendrickx M, de Genst E, Leyns L.
Biochem Biophys Res Commun. 2007 Jun 15;357(4):1119-23. Epub 2007 Apr 19.PMID: 17462603 [PubMed - indexed for MEDLINE]Related articles
Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling.
Swain RK, Katoh M, Medina A, Steinbeisser H.
Cell Commun Signal. 2005 Oct 19;3:12.PMID: 16236168 [PubMed]Related articlesFree article
The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.
Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M.
PLoS One. 2009;4(1):e4273. Epub 2009 Jan 26.PMID: 19169355 [PubMed - indexed for MEDLINE]Related articlesFree article
Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development.
Chen Y, Stump RJ, Lovicu FJ, McAvoy JW.
Int J Dev Biol. 2004;48(8-9):867-77.PMID: 15558478 [PubMed - indexed for MEDLINE]Related articlesFree article
SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.
Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, Liu HS, Chu DW, Lin YW.
Gynecol Oncol. 2009 Mar;112(3):646-53. Epub 2008 Dec 18.PMID: 19095296 [PubMed - indexed for MEDLINE]Related articles
SFRP1 is required for the proper establishment of the eye field in the medaka fish.
Esteve P, Lopez-Rios J, Bovolenta P.
Mech Dev. 2004 Jul;121(7-8):687-701.PMID: 15210177 [PubMed - indexed for MEDLINE]Related articles
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