PubMed

Targeting CD22 reprograms B-cells and reverses autoimmune diabetes.

Fiorina P, Vergani A, Dada S, Jurewicz M, Wong M, Law K, Wu E, Tian Z, Abdi R, Guleria I, Rodig S, Dunussi-Joannopoulos K, Bluestone J, Sayegh MH.

Diabetes. 2008 Nov;57(11):3013-24. Epub 2008 Aug 8.PMID: 18689692 [PubMed - indexed for MEDLINE]Related articlesFree article

Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes.

O'Neill SK, Liu E, Cambier JC.

Curr Opin Endocrinol Diabetes Obes. 2009 Aug;16(4):293-8. Review.PMID: 19502979 [PubMed - indexed for MEDLINE]Related articles

Upregulating CD4+CD25+FOXP3+ regulatory T cells in pancreatic lymph nodes in diabetic NOD mice by adjuvant immunotherapy.

Tian B, Hao J, Zhang Y, Tian L, Yi H, O'Brien TD, Sutherland DE, Hering BJ, Guo Z.

Transplantation. 2009 Jan 27;87(2):198-206.PMID: 19155973 [PubMed - indexed for MEDLINE]Related articles

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors.

Christianson SW, Shultz LD, Leiter EH.

Diabetes. 1993 Jan;42(1):44-55.PMID: 8093606 [PubMed - indexed for MEDLINE]Related articles

Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice.

Makhlouf L, Grey ST, Dong V, Csizmadia E, Arvelo MB, Auchincloss H Jr, Ferran C, Sayegh MH.

Transplantation. 2004 Apr 15;77(7):990-7.PMID: 15087759 [PubMed - indexed for MEDLINE]Related articles

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM.

J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8.PMID: 17210729 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody.

Alwayn IP, Xu Y, Basker M, Wu C, Buhler L, Lambrigts D, Treter S, Harper D, Kitamura H, Vitetta ES, Abraham S, Awwad M, White-Scharf ME, Sachs DH, Thall A, Cooper DK.

Xenotransplantation. 2001 Aug;8(3):157-71.PMID: 11472623 [PubMed - indexed for MEDLINE]Related articles

Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.

Luo X, Tarbell KV, Yang H, Pothoven K, Bailey SL, Ding R, Steinman RM, Suthanthiran M.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2821-6. Epub 2007 Feb 16.PMID: 17307871 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells.

Mariño E, Villanueva J, Walters S, Liuwantara D, Mackay F, Grey ST.

Diabetes. 2009 Jul;58(7):1568-77. Epub 2009 Mar 31.PMID: 19336675 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.

Parker MJ, Xue S, Alexander JJ, Wasserfall CH, Campbell-Thompson ML, Battaglia M, Gregori S, Mathews CE, Song S, Troutt M, Eisenbeis S, Williams J, Schatz DA, Haller MJ, Atkinson MA.

Diabetes. 2009 Oct;58(10):2277-84. Epub 2009 Jul 23.PMID: 19628781 [PubMed - indexed for MEDLINE]Related articles

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.

Hu CY, Rodriguez-Pinto D, Du W, Ahuja A, Henegariu O, Wong FS, Shlomchik MJ, Wen L.

J Clin Invest. 2007 Dec;117(12):3857-67.PMID: 18060033 [PubMed - indexed for MEDLINE]Related articlesFree article

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

Xiu Y, Wong CP, Bouaziz JD, Hamaguchi Y, Wang Y, Pop SM, Tisch RM, Tedder TF.

J Immunol. 2008 Mar 1;180(5):2863-75.PMID: 18292508 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells.

Mellanby RJ, Thomas D, Phillips JM, Cooke A.

Immunology. 2007 May;121(1):15-28.PMID: 17428252 [PubMed - indexed for MEDLINE]Related articlesFree article

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice.

Noorchashm H, Noorchashm N, Kern J, Rostami SY, Barker CF, Naji A.

Diabetes. 1997 Jun;46(6):941-6.PMID: 9166663 [PubMed - indexed for MEDLINE]Related articles

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice.

Greeley SA, Moore DJ, Noorchashm H, Noto LE, Rostami SY, Schlachterman A, Song HK, Koeberlein B, Barker CF, Naji A.

J Immunol. 2001 Oct 15;167(8):4351-7.PMID: 11591759 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.

Arefanian H, Tredget EB, Rajotte RV, Korbutt GS, Gill RG, Rayat GR.

Cell Transplant. 2007;16(8):787-98.PMID: 18087999 [PubMed - indexed for MEDLINE]Related articles

Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice.

Drage M, Zaccone P, Phillips JM, Nicoletti F, Dawson J, Andrew Bradley J, Cooke A.

Transplantation. 2002 Sep 15;74(5):611-9.PMID: 12352875 [PubMed - indexed for MEDLINE]Related articles

Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies.

Mottram PL, Murray-Segal LJ, Han W, Maguire J, Stein-Oakley AN.

Transpl Immunol. 2002 Jun;10(1):63-72.PMID: 12182467 [PubMed - indexed for MEDLINE]Related articles

CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

Mukherjee R, Chaturvedi P, Qin HY, Singh B.

J Autoimmun. 2003 Nov;21(3):221-37.PMID: 14599847 [PubMed - indexed for MEDLINE]Related articles

Role of L-selectin in the development of autoimmune diabetes in non-obese diabetic mice.

Mora C, Grewal IS, Wong FS, Flavell RA.

Int Immunol. 2004 Feb;16(2):257-64.PMID: 14734611 [PubMed - indexed for MEDLINE]Related articlesFree article