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    Results: 1 to 20 of 225

    1.

    Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.

    Heathfield SK, Le Maitre CL, Hoyland JA.

    Arthritis Res Ther. 2008;10(4):R87. Epub 2008 Aug 5.

    PMID:
    18681962
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration.

    Le Maitre CL, Freemont AJ, Hoyland JA.

    Arthritis Res Ther. 2007;9(3):R45.

    PMID:
    17498290
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc.

    Purmessur D, Freemont AJ, Hoyland JA.

    Arthritis Res Ther. 2008;10(4):R99. Epub 2008 Aug 27.

    PMID:
    18727839
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs.

    Kim KW, Chung HN, Ha KY, Lee JS, Kim YY.

    Spine J. 2009 Aug;9(8):658-66. Epub 2009 Jun 21.

    PMID:
    19540815
    [PubMed - indexed for MEDLINE]
    5.

    Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.

    Le Maitre CL, Hoyland JA, Freemont AJ.

    Arthritis Res Ther. 2007;9(4):R77.

    PMID:
    17688691
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration.

    Ali R, Le Maitre CL, Richardson SM, Hoyland JA, Freemont AJ.

    Biotech Histochem. 2008;83(5):239-45.

    PMID:
    19016368
    [PubMed - indexed for MEDLINE]
    7.

    Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc.

    Le Maitre CL, Richardson SM, Baird P, Freemont AJ, Hoyland JA.

    J Pathol. 2005 Dec;207(4):445-52.

    PMID:
    16278806
    [PubMed - indexed for MEDLINE]
    8.

    Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration.

    Rutges J, Creemers LB, Dhert W, Milz S, Sakai D, Mochida J, Alini M, Grad S.

    Osteoarthritis Cartilage. 2010 Mar;18(3):416-23. Epub 2009 Oct 1.

    PMID:
    19833252
    [PubMed - indexed for MEDLINE]
    9.

    Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs.

    Gruber HE, Ingram JA, Norton HJ, Hanley EN Jr.

    Spine (Phila Pa 1976). 2007 Feb 1;32(3):321-7.

    PMID:
    17268263
    [PubMed - indexed for MEDLINE]
    10.

    Human cells derived from degenerate intervertebral discs respond differently to those derived from non-degenerate intervertebral discs following application of dynamic hydrostatic pressure.

    Le Maitre CL, Frain J, Fotheringham AP, Freemont AJ, Hoyland JA.

    Biorheology. 2008;45(5):563-75.

    PMID:
    19065005
    [PubMed - indexed for MEDLINE]
    11.

    Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining.

    Sharp CA, Roberts S, Evans H, Brown SJ.

    Eur Spine J. 2009 Nov;18(11):1587-94. Epub 2009 Jun 11.

    PMID:
    19517141
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption.

    Weiler C, Nerlich AG, Zipperer J, Bachmeier BE, Boos N.

    Eur Spine J. 2002 Aug;11(4):308-20. Epub 2002 Jul 9.

    PMID:
    12193991
    [PubMed - indexed for MEDLINE]
    13.

    Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs.

    Le Maitre CL, Frain J, Millward-Sadler J, Fotheringham AP, Freemont AJ, Hoyland JA.

    Arthritis Rheum. 2009 Feb;60(2):460-9.

    PMID:
    19180480
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Expression of proteinase-activated receptor-2 in the intervertebral disc.

    Iida R, Akeda K, Kasai Y, Masuda K, Morimoto R, Sakakibara T, Sato M, Uchida A.

    Spine (Phila Pa 1976). 2009 Mar 1;34(5):470-8.

    PMID:
    19247167
    [PubMed - indexed for MEDLINE]
    15.

    The expression of anabolic cytokines in intervertebral discs in age-related degeneration.

    Murakami H, Yoon ST, Attallah-Wasif ES, Tsai KJ, Fei Q, Hutton WC.

    Spine (Phila Pa 1976). 2006 Jul 15;31(16):1770-4.

    PMID:
    16845348
    [PubMed - indexed for MEDLINE]
    16.

    Senescence in human intervertebral discs.

    Roberts S, Evans EH, Kletsas D, Jaffray DC, Eisenstein SM.

    Eur Spine J. 2006 Aug;15 Suppl 3:S312-6. Epub 2006 Jun 14.

    PMID:
    16773379
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Human anulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype.

    Kluba T, Niemeyer T, Gaissmaier C, GrĂ¼nder T.

    Spine (Phila Pa 1976). 2005 Dec 15;30(24):2743-8.

    PMID:
    16371897
    [PubMed - indexed for MEDLINE]
    18.

    Peroxynitrite induces gene expression in intervertebral disc cells.

    Poveda L, Hottiger M, Boos N, Wuertz K.

    Spine (Phila Pa 1976). 2009 May 15;34(11):1127-33.

    PMID:
    19407676
    [PubMed - indexed for MEDLINE]
    19.

    Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells.

    Le Maitre CL, Freemont AJ, Hoyland JA.

    Arthritis Res Ther. 2009;11(5):R137. Epub 2009 Sep 15.

    PMID:
    19754961
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    DR5 and DcR2 are expressed in human lumbar intervertebral discs.

    Chen B, Ma B, Yang S, Xing X, Gu R, Hu Y.

    Spine (Phila Pa 1976). 2009 Sep 1;34(19):E677-81.

    PMID:
    19730199
    [PubMed - indexed for MEDLINE]

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