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    Results: 1 to 20 of 215

    1.

    Metabolic changes in schizophrenia and human brain evolution.

    Khaitovich P, Lockstone HE, Wayland MT, Tsang TM, Jayatilaka SD, Guo AJ, Zhou J, Somel M, Harris LW, Holmes E, Pääbo S, Bahn S.

    Genome Biol. 2008;9(8):R124. Epub 2008 Aug 5.

    PMID:
    18681948
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Intra- and interspecific variation in primate gene expression patterns.

    Enard W, Khaitovich P, Klose J, Zöllner S, Heissig F, Giavalisco P, Nieselt-Struwe K, Muchmore E, Varki A, Ravid R, Doxiadis GM, Bontrop RE, Pääbo S.

    Science. 2002 Apr 12;296(5566):340-3.

    PMID:
    11951044
    [PubMed - indexed for MEDLINE]
    3.

    Expression profiling in primates reveals a rapid evolution of human transcription factors.

    Gilad Y, Oshlack A, Smyth GK, Speed TP, White KP.

    Nature. 2006 Mar 9;440(7081):242-5.

    PMID:
    16525476
    [PubMed - indexed for MEDLINE]
    4.

    Differences in human and chimpanzee gene expression patterns define an evolving network of transcription factors in brain.

    Nowick K, Gernat T, Almaas E, Stubbs L.

    Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22358-63. Epub 2009 Dec 10.

    PMID:
    20007773
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

    Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, Franz H, Weiss G, Lachmann M, Pääbo S.

    Science. 2005 Sep 16;309(5742):1850-4. Epub 2005 Sep 1.

    PMID:
    16141373
    [PubMed - indexed for MEDLINE]
    6.

    Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cells.

    Altar CA, Hunt RA, Jurata LW, Webster MJ, Derby E, Gallagher P, Lemire A, Brockman J, Laeng P.

    Biol Psychiatry. 2008 Dec 15;64(12):1077-87. Epub 2008 Oct 30.

    PMID:
    18973876
    [PubMed - indexed for MEDLINE]
    7.

    No accelerated evolution of 3'UTR region in human for brain-expressed genes.

    Li Y, Su B.

    Gene. 2006 Nov 15;383:38-42. Epub 2006 Jul 20.

    PMID:
    16962257
    [PubMed - indexed for MEDLINE]
    8.

    Conservation and evolution of gene coexpression networks in human and chimpanzee brains.

    Oldham MC, Horvath S, Geschwind DH.

    Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17973-8. Epub 2006 Nov 13.

    PMID:
    17101986
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Transcriptional neoteny in the human brain.

    Somel M, Franz H, Yan Z, Lorenc A, Guo S, Giger T, Kelso J, Nickel B, Dannemann M, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P.

    Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5743-8. Epub 2009 Mar 23.

    PMID:
    19307592
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Elevated gene expression levels distinguish human from non-human primate brains.

    Cáceres M, Lachuer J, Zapala MA, Redmond JC, Kudo L, Geschwind DH, Lockhart DJ, Preuss TM, Barlow C.

    Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13030-5. Epub 2003 Oct 13.

    PMID:
    14557539
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains.

    Popesco MC, Maclaren EJ, Hopkins J, Dumas L, Cox M, Meltesen L, McGavran L, Wyckoff GJ, Sikela JM.

    Science. 2006 Sep 1;313(5791):1304-7.

    PMID:
    16946073
    [PubMed - indexed for MEDLINE]
    12.

    Detecting lineage-specific adaptive evolution of brain-expressed genes in human using rhesus macaque as outgroup.

    Yu XJ, Zheng HK, Wang J, Wang W, Su B.

    Genomics. 2006 Dec;88(6):745-51. Epub 2006 Jul 18.

    PMID:
    16857340
    [PubMed - indexed for MEDLINE]
    13.

    Toward a neutral evolutionary model of gene expression.

    Khaitovich P, Pääbo S, Weiss G.

    Genetics. 2005 Jun;170(2):929-39. Epub 2005 Apr 16.

    PMID:
    15834146
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Evolution of primate gene expression.

    Khaitovich P, Enard W, Lachmann M, Pääbo S.

    Nat Rev Genet. 2006 Sep;7(9):693-702. Review.

    PMID:
    16921347
    [PubMed - indexed for MEDLINE]
    15.

    A neutral model of transcriptome evolution.

    Khaitovich P, Weiss G, Lachmann M, Hellmann I, Enard W, Muetzel B, Wirkner U, Ansorge W, Pääbo S.

    PLoS Biol. 2004 May;2(5):E132. Epub 2004 May 11.

    PMID:
    15138501
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Comparative genomics. Gene expression differs in human and chimp brains.

    Normile D.

    Science. 2001 Apr 6;292(5514):44-5. No abstract available.

    PMID:
    11294209
    [PubMed - indexed for MEDLINE]
    17.

    Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.

    Cáceres M, Suwyn C, Maddox M, Thomas JW, Preuss TM.

    Cereb Cortex. 2007 Oct;17(10):2312-21. Epub 2006 Dec 20.

    PMID:
    17182969
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Human brain evolution: insights from microarrays.

    Preuss TM, Cáceres M, Oldham MC, Geschwind DH.

    Nat Rev Genet. 2004 Nov;5(11):850-60. Review.

    PMID:
    15520794
    [PubMed - indexed for MEDLINE]
    19.

    Adaptive evolution of genes underlying schizophrenia.

    Crespi B, Summers K, Dorus S.

    Proc Biol Sci. 2007 Nov 22;274(1627):2801-10.

    PMID:
    17785269
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    [Gene-expression profiling in schizophrenia: an overview].

    Verveer J, Huizer K, Fekkes D, van Beveren NJ.

    Tijdschr Psychiatr. 2007;49(1):7-16; discussion 17-9. Review. Dutch.

    PMID:
    17225200
    [PubMed - indexed for MEDLINE]
    Free Article

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