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    Results: 1 to 20 of 113

    1.

    Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

    Bugger H, Boudina S, Hu XX, Tuinei J, Zaha VG, Theobald HA, Yun UJ, McQueen AP, Wayment B, Litwin SE, Abel ED.

    Diabetes. 2008 Nov;57(11):2924-32. Epub 2008 Aug 4.PMID: 18678617 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

    Boudina S, Sena S, Theobald H, Sheng X, Wright JJ, Hu XX, Aziz S, Johnson JI, Bugger H, Zaha VG, Abel ED.

    Diabetes. 2007 Oct;56(10):2457-66. Epub 2007 Jul 10.PMID: 17623815 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity.

    Boudina S, Sena S, O'Neill BT, Tathireddy P, Young ME, Abel ED.

    Circulation. 2005 Oct 25;112(17):2686-95.PMID: 16246967 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart.

    Murray AJ, Cole MA, Lygate CA, Carr CA, Stuckey DJ, Little SE, Neubauer S, Clarke K.

    J Mol Cell Cardiol. 2008 Apr;44(4):694-700. Epub 2008 Feb 9.PMID: 18328500 [PubMed - indexed for MEDLINE]Related articles

    5.

    Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration.

    Anderson EJ, Yamazaki H, Neufer PD.

    J Biol Chem. 2007 Oct 26;282(43):31257-66. Epub 2007 Aug 30.PMID: 17761668 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

    Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

    Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.PMID: 17131143 [PubMed - indexed for MEDLINE]Related articles

    7.

    Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice.

    Bugger H, Chen D, Riehle C, Soto J, Theobald HA, Hu XX, Ganesan B, Weimer BC, Abel ED.

    Diabetes. 2009 Sep;58(9):1986-97. Epub 2009 Jun 19.PMID: 19542201 [PubMed - indexed for MEDLINE]Related articles

    8.

    Regulation of mitochondrial uncoupling respiration during exercise in rat heart: role of reactive oxygen species (ROS) and uncoupling protein 2.

    Bo H, Jiang N, Ma G, Qu J, Zhang G, Cao D, Wen L, Liu S, Ji LL, Zhang Y.

    Free Radic Biol Med. 2008 Apr 1;44(7):1373-81. Epub 2008 Jan 4.PMID: 18226608 [PubMed - indexed for MEDLINE]Related articles

    9.

    Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury.

    Serviddio G, Bellanti F, Tamborra R, Rollo T, Capitanio N, Romano AD, Sastre J, Vendemiale G, Altomare E.

    Gut. 2008 Jul;57(7):957-65. Epub 2008 Feb 28.PMID: 18308829 [PubMed - indexed for MEDLINE]Related articles

    10.

    Upregulation of uncoupling protein-3 in skeletal muscle during exercise: a potential antioxidant function.

    Jiang N, Zhang G, Bo H, Qu J, Ma G, Cao D, Wen L, Liu S, Ji LL, Zhang Y.

    Free Radic Biol Med. 2009 Jan 15;46(2):138-45. Epub 2008 Oct 9.PMID: 18977294 [PubMed - indexed for MEDLINE]Related articles

    11.

    Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells.

    Friederich M, Fasching A, Hansell P, Nordquist L, Palm F.

    Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):935-40. Epub 2008 Apr 7.PMID: 18439413 [PubMed - indexed for MEDLINE]Related articles

    12.

    Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

    Mazumder PK, O'Neill BT, Roberts MW, Buchanan J, Yun UJ, Cooksey RC, Boudina S, Abel ED.

    Diabetes. 2004 Sep;53(9):2366-74.PMID: 15331547 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice.

    How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS.

    Diabetes. 2006 Feb;55(2):466-73.PMID: 16443782 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.

    Boudina S, Bugger H, Sena S, O'Neill BT, Zaha VG, Ilkun O, Wright JJ, Mazumder PK, Palfreyman E, Tidwell TJ, Theobald H, Khalimonchuk O, Wayment B, Sheng X, Rodnick KJ, Centini R, Chen D, Litwin SE, Weimer BE, Abel ED.

    Circulation. 2009 Mar 10;119(9):1272-83. Epub 2009 Feb 23.PMID: 19237663 [PubMed - indexed for MEDLINE]Related articles

    15.

    Hypoxia-induced decrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling.

    Essop MF, Razeghi P, McLeod C, Young ME, Taegtmeyer H, Sack MN.

    Biochem Biophys Res Commun. 2004 Feb 6;314(2):561-4.PMID: 14733944 [PubMed - indexed for MEDLINE]Related articles

    16.

    Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells.

    MacLellan JD, Gerrits MF, Gowing A, Smith PJ, Wheeler MB, Harper ME.

    Diabetes. 2005 Aug;54(8):2343-50.PMID: 16046300 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.

    Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB.

    J Biol Chem. 2004 Dec 3;279(49):51049-56. Epub 2004 Sep 23.PMID: 15448158 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes.

    Ye G, Metreveli NS, Donthi RV, Xia S, Xu M, Carlson EC, Epstein PN.

    Diabetes. 2004 May;53(5):1336-43.PMID: 15111504 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mitochondrial adaptations to obesity-related oxidant stress.

    Yang S, Zhu H, Li Y, Lin H, Gabrielson K, Trush MA, Diehl AM.

    Arch Biochem Biophys. 2000 Jun 15;378(2):259-68.PMID: 10860543 [PubMed - indexed for MEDLINE]Related articles

    20.

    Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding.

    Wright JJ, Kim J, Buchanan J, Boudina S, Sena S, Bakirtzi K, Ilkun O, Theobald HA, Cooksey RC, Kandror KV, Abel ED.

    Cardiovasc Res. 2009 May 1;82(2):351-60. Epub 2009 Jan 15.PMID: 19147655 [PubMed - indexed for MEDLINE]Related articles

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