PubMed

Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.

Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D, Lee CH, Hu FB.

Diabetes. 2008 Nov;57(11):3145-51. Epub 2008 Jul 22.PMID: 18647953 [PubMed - indexed for MEDLINE]Related articlesFree article

The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients.

Zabena C, González-Sánchez JL, Martínez-Larrad MT, Torres-García A, Alvarez-Fernández-Represa J, Corbatón-Anchuelo A, Pérez-Barba M, Serrano-Ríos M.

Obes Surg. 2009 Jan;19(1):87-95. Epub 2008 Oct 15.PMID: 18855084 [PubMed - indexed for MEDLINE]Related articles

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.

Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbaek A, Lauritzen T, Hansen L, Jørgensen T, Pedersen O, Hansen T.

Diabetes. 2008 Jan;57(1):95-101. Epub 2007 Oct 17.PMID: 17942823 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of Fto/Ftm gene expression in mice and humans.

Stratigopoulos G, Padilla SL, LeDuc CA, Watson E, Hattersley AT, McCarthy MI, Zeltser LM, Chung WK, Leibel RL.

Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1185-96. Epub 2008 Feb 6. Erratum in: Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1360-3. PMID: 18256137 [PubMed - indexed for MEDLINE]Related articles

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.

Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Lindgren CM, Freathy RM, Koch K, Ouwehand WH, Karpe F, Conway GS, Wass JA, Järvelin MR, Franks S, McCarthy MI.

Diabetologia. 2008 Jul;51(7):1153-8. Epub 2008 May 14.PMID: 18478198 [PubMed - indexed for MEDLINE]Related articles

The fat mass- and obesity-associated locus and dietary intake in children.

Timpson NJ, Emmett PM, Frayling TM, Rogers I, Hattersley AT, McCarthy MI, Davey Smith G.

Am J Clin Nutr. 2008 Oct;88(4):971-8.PMID: 18842783 [PubMed - indexed for MEDLINE]Related articlesFree article

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.

Kring SI, Holst C, Zimmermann E, Jess T, Berentzen T, Toubro S, Hansen T, Astrup A, Pedersen O, Sørensen TI.

PLoS One. 2008 Aug 13;3(8):e2958.PMID: 18698412 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

Grunnet LG, Nilsson E, Ling C, Hansen T, Pedersen O, Groop L, Vaag A, Poulsen P.

Diabetes. 2009 Oct;58(10):2402-8. Epub 2009 Jul 8.PMID: 19587359 [PubMed - indexed for MEDLINE]Related articles

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P.

J Mol Med. 2009 May;87(5):537-46. Epub 2009 Mar 3.PMID: 19255736 [PubMed - indexed for MEDLINE]Related articles

Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study.

Legry V, Cottel D, Ferrières J, Arveiler D, Andrieux N, Bingham A, Wagner A, Ruidavets JB, Ducimetière P, Amouyel P, Meirhaeghe A.

Metabolism. 2009 Jul;58(7):971-5.PMID: 19375760 [PubMed - indexed for MEDLINE]Related articles

The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: the Finnish Diabetes Prevention Study.

Lappalainen TJ, Tolppanen AM, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Pulkkinen L, Eriksson JG, Laakso M, Gylling H, Uusitupa M; Finnish Diabetes Prevention Study Group.

Obesity (Silver Spring). 2009 Apr;17(4):832-6. Epub 2009 Jan 29.PMID: 19180072 [PubMed - indexed for MEDLINE]Related articles

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.

Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM.

Diabetes. 2008 Aug;57(8):2245-52. Epub 2008 May 16.PMID: 18487448 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC.

Diabetes. 2008 Apr;57(4):1147-50. Epub 2008 Mar 3.PMID: 18316358 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G x E) interaction.

Cornes BK, Lind PA, Medland SE, Montgomery GW, Nyholt DR, Martin NG.

Int J Obes (Lond). 2009 Jan;33(1):75-9. Epub 2008 Nov 25.PMID: 19030008 [PubMed - indexed for MEDLINE]Related articles

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, Gerken T, Lee A, Moir L, Mecinović J, Quwailid MM, Schofield CJ, Ashcroft FM, Cox RD.

PLoS Genet. 2009 Aug;5(8):e1000599. Epub 2009 Aug 14.PMID: 19680540 [PubMed - indexed for MEDLINE]Related articlesFree article

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis.

Wåhlén K, Sjölin E, Hoffstedt J.

J Lipid Res. 2008 Mar;49(3):607-11. Epub 2007 Nov 29.PMID: 18048838 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels.

Fisher E, Schulze MB, Stefan N, Häring HU, Döring F, Joost HG, Al-Hasani H, Boeing H, Pischon T.

Obesity (Silver Spring). 2009 Feb;17(2):330-4. Epub 2008 Oct 23.PMID: 18948966 [PubMed - indexed for MEDLINE]Related articles

FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.

Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, F Tinker L, Liu S.

Obesity (Silver Spring). 2008 Nov;16(11):2472-80. Epub 2008 Sep 11.PMID: 18787525 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.

Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2008 May;57(5):1419-26. Epub 2008 Mar 17.PMID: 18346983 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.

Jonsson A, Renström F, Lyssenko V, Brito EC, Isomaa B, Berglund G, Nilsson PM, Groop L, Franks PW.

Diabetologia. 2009 Jul;52(7):1334-8. Epub 2009 Apr 17.PMID: 19373445 [PubMed - indexed for MEDLINE]Related articles