PubMed

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response.

Visciano ML, Tuen M, Chen PD, Hioe CE.

Infect Agent Cancer. 2008 Jul 18;3:11.PMID: 18638381 [PubMed - in process]Related articlesFree article

In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120.

Visciano ML, Tuen M, Gorny MK, Hioe CE.

Virology. 2008 Mar 15;372(2):409-20. Epub 2007 Dec 4.PMID: 18054978 [PubMed - indexed for MEDLINE]Related articlesFree article

The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.

Hioe CE, Visciano ML, Kumar R, Liu J, Mack EA, Simon RE, Levy DN, Tuen M.

Vaccine. 2009 Dec 11;28(2):352-60. Epub 2009 Oct 29.PMID: 19879224 [PubMed - indexed for MEDLINE]Related articles

Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site.

Burioni R, Mancini N, De Marco D, Clementi N, Perotti M, Nitti G, Sassi M, Canducci F, Shvela K, Bagnarelli P, Mascola JR, Clementi M.

PLoS One. 2008;3(10):e3423. Epub 2008 Oct 16.PMID: 18923648 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of antibodies that inhibit HIV gp120 antigen processing and presentation.

Tuen M, Visciano ML, Chien PC Jr, Cohen S, Chen PD, Robinson J, He Y, Pinter A, Gorny MK, Hioe CE.

Eur J Immunol. 2005 Sep;35(9):2541-51.PMID: 16106369 [PubMed - indexed for MEDLINE]Related articles

Temporal development and prognostic value of antibody response to the major neutralizing epitopes of gp120 during HIV-1 infection.

Turbica I, Simon F, Besnier JM, LeJeune B, Choutet P, Goudeau A, Barin F.

J Med Virol. 1997 Jul;52(3):309-15.PMID: 9210041 [PubMed - indexed for MEDLINE]Related articles

Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site.

Herrera C, Spenlehauer C, Fung MS, Burton DR, Beddows S, Moore JP.

J Virol. 2003 Jan;77(2):1084-91.PMID: 12502824 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120.

Hioe CE, Tuen M, Chien PC Jr, Jones G, Ratto-Kim S, Norris PJ, Moretto WJ, Nixon DF, Gorny MK, Zolla-Pazner S.

J Virol. 2001 Nov;75(22):10950-7.PMID: 11602735 [PubMed - indexed for MEDLINE]Related articlesFree article

Carrier-dependent specificity of antibodies to a conserved peptide determinant of gp120.

Karle S, Nishiyama Y, Taguchi H, Zhou YX, Luo J, Planque S, Hanson C, Paul S.

Vaccine. 2003 Mar 7;21(11-12):1213-8.PMID: 12559800 [PubMed - indexed for MEDLINE]Related articles

Anti-CD4-binding domain antibodies complexed with HIV type 1 glycoprotein 120 inhibit CD4+ T cell-proliferative responses to glycoprotein 120.

Hioe CE, Jones GJ, Rees AD, Ratto-Kim S, Birx D, Münz C, Gorny MK, Tuen M, Zolla-Pazner S.

AIDS Res Hum Retroviruses. 2000 Jun 10;16(9):893-905.PMID: 10875615 [PubMed - indexed for MEDLINE]Related articles

HIV-1-specific immunity in persistently seronegative individuals at high risk for HIV infection.

Beretta A, Furci L, Burastero S, Cosma A, Dinelli ME, Lopalco L, DeSantis C, Tambussi G, Carrow E, Sabbatani S, Clerici M, Lazzarin A, Siccardi AG.

Immunol Lett. 1996 Jun;51(1-2):39-43.PMID: 8811343 [PubMed - indexed for MEDLINE]Related articles

Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes.

Li H, Xu CF, Blais S, Wan Q, Zhang HT, Landry SJ, Hioe CE.

J Immunol. 2009 May 15;182(10):6369-78.PMID: 19414790 [PubMed - indexed for MEDLINE]Related articles

Identification of an N-linked glycosylation in the C4 region of HIV-1 envelope gp120 that is critical for recognition of neighboring CD4 T cell epitopes.

Li H, Chien PC Jr, Tuen M, Visciano ML, Cohen S, Blais S, Xu CF, Zhang HT, Hioe CE.

J Immunol. 2008 Mar 15;180(6):4011-21.PMID: 18322210 [PubMed - indexed for MEDLINE]Related articlesFree article

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

Sterjovski J, Churchill MJ, Ellett A, Gray LR, Roche MJ, Dunfee RL, Purcell DF, Saksena N, Wang B, Sonza S, Wesselingh SL, Karlsson I, Fenyo EM, Gabuzda D, Cunningham AL, Gorry PR.

Retrovirology. 2007 Dec 12;4:89.PMID: 18076768 [PubMed - indexed for MEDLINE]Related articlesFree article

Recognition of HIV glycoprotein gp120 by T cells. Role of monocyte CD4 in the presentation of gp120.

Siliciano RF, Knall C, Lawton T, Berman P, Gregory T, Reinherz EL.

J Immunol. 1989 Mar 1;142(5):1506-11.PMID: 2537355 [PubMed - indexed for MEDLINE]Related articles

HIV-1-infected patients with envelope-specific lymphoproliferation or long-term nonprogression lack antibodies suppressing glycoprotein 120 antigen presentation.

Chien PC Jr, Chen D, Chen PD, Tuen M, Cohen S, Migueles SA, Connors M, Rosenberg E, Malhotra U, Gonzalez C, Hioe CE.

J Infect Dis. 2004 Mar 1;189(5):852-61. Epub 2004 Feb 6.PMID: 14976603 [PubMed - indexed for MEDLINE]Related articles

High levels of antibodies to the CD4 binding domain of human immunodeficiency virus type 1 glycoprotein 120 are associated with faster disease progression.

Chien PC Jr, Cohen S, Kleeberger C, Giorgi J, Phair J, Zolla-Pazner S, Hioe CE.

J Infect Dis. 2002 Jul 15;186(2):205-13. Epub 2002 Jul 3.PMID: 12134256 [PubMed - indexed for MEDLINE]Related articles

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.

Sanders RW, van Anken E, Nabatov AA, Liscaljet IM, Bontjer I, Eggink D, Melchers M, Busser E, Dankers MM, Groot F, Braakman I, Berkhout B, Paxton WA.

Retrovirology. 2008 Jan 31;5:10.PMID: 18237398 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunogenicity of HIV type 1 gp120 CD4 binding site phage mimotopes.

Dorgham K, Dogan I, Bitton N, Parizot C, Cardona V, Debré P, Hartley O, Gorochov G.

AIDS Res Hum Retroviruses. 2005 Jan;21(1):82-92.PMID: 15665647 [PubMed - indexed for MEDLINE]Related articles

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

Binley JM, Lybarger EA, Crooks ET, Seaman MS, Gray E, Davis KL, Decker JM, Wycuff D, Harris L, Hawkins N, Wood B, Nathe C, Richman D, Tomaras GD, Bibollet-Ruche F, Robinson JE, Morris L, Shaw GM, Montefiori DC, Mascola JR.

J Virol. 2008 Dec;82(23):11651-68. Epub 2008 Sep 24.PMID: 18815292 [PubMed - indexed for MEDLINE]Related articlesFree article