PubMed

Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease.

Xue M, Qian Q, Adaikalakoteswari A, Rabbani N, Babaei-Jadidi R, Thornalley PJ.

Diabetes. 2008 Oct;57(10):2809-17. Epub 2008 Jul 15.PMID: 18633117 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells.

Hsieh CY, Hsiao HY, Wu WY, Liu CA, Tsai YC, Chao YJ, Wang DL, Hsieh HJ.

J Biomed Sci. 2009 Jan 22;16:12.PMID: 19272177 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulforaphane inhibits TNF-alpha-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells.

Chen XL, Dodd G, Kunsch C.

Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11.PMID: 19277846 [PubMed - indexed for MEDLINE]Related articles

KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells.

Fledderus JO, Boon RA, Volger OL, Hurttila H, Ylä-Herttuala S, Pannekoek H, Levonen AL, Horrevoets AJ.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1339-46. Epub 2008 May 8.PMID: 18467642 [PubMed - indexed for MEDLINE]Related articlesFree article

Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species.

Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, Ishii T, Kodama T, Noguchi N.

Free Radic Biol Med. 2007 Jan 15;42(2):260-9. Epub 2006 Oct 20.PMID: 17189831 [PubMed - indexed for MEDLINE]Related articles

NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia- induced brain endothelial cell apoptosis.

Okouchi M, Okayama N, Alexander JS, Aw TY.

Curr Neurovasc Res. 2006 Nov;3(4):249-61.PMID: 17109620 [PubMed - indexed for MEDLINE]Related articles

Protective effect of sulforaphane on indomethacin-induced cytotoxicity via heme oxygenase-1 expression in human intestinal Int 407 cells.

Yeh CT, Chiu HF, Yen GC.

Mol Nutr Food Res. 2009 Sep;53(9):1166-76.PMID: 19653226 [PubMed - indexed for MEDLINE]Related articles

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo.

Jyrkkänen HK, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen AL.

Circ Res. 2008 Jul 3;103(1):e1-9. Epub 2008 Jun 5.PMID: 18535259 [PubMed - indexed for MEDLINE]Related articlesFree article

Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells.

Kivelä AM, Kansanen E, Jyrkkänen HK, Nurmi T, Ylä-Herttuala S, Levonen AL.

J Nutr. 2008 Jul;138(7):1263-8.PMID: 18567745 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.

Yeh CT, Yen GC.

Carcinogenesis. 2005 Dec;26(12):2138-48. Epub 2005 Jul 20.PMID: 16033772 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription factor Nrf2 activation by deltamethrin in PC12 cells: Involvement of ROS.

Li HY, Wu SY, Shi N.

Toxicol Lett. 2007 Jun 15;171(1-2):87-98. Epub 2007 Apr 27.PMID: 17540521 [PubMed - indexed for MEDLINE]Related articles

Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE.

Wang L, Chen Y, Sternberg P, Cai J.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1671-8.PMID: 18385090 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells.

Li CQ, Kim MY, Godoy LC, Thiantanawat A, Trudel LJ, Wogan GN.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14547-51. Epub 2009 Aug 11.PMID: 19706542 [PubMed - indexed for MEDLINE]Related articles

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.

Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S.

Cancer Res. 2002 Sep 15;62(18):5196-203.PMID: 12234984 [PubMed - indexed for MEDLINE]Related articlesFree article

Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress.

Numazawa S, Ishikawa M, Yoshida A, Tanaka S, Yoshida T.

Am J Physiol Cell Physiol. 2003 Aug;285(2):C334-42. Epub 2003 Apr 16.PMID: 12700136 [PubMed - indexed for MEDLINE]Related articlesFree article

Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cells.

Zhang HS, Wang SQ.

Biochem Pharmacol. 2007 May 1;73(9):1358-66. Epub 2007 Jan 7.PMID: 17303087 [PubMed - indexed for MEDLINE]Related articles

Heat stress activates interleukin-8 and the antioxidant system via Nrf2 pathways in human dental pulp cells.

Chang SW, Lee SI, Bae WJ, Min KS, Shin ES, Oh GS, Pae HO, Kim EC.

J Endod. 2009 Sep;35(9):1222-8.PMID: 19720220 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.

Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, Seo HG.

Free Radic Biol Med. 2007 Aug 15;43(4):535-45. Epub 2007 May 16.PMID: 17640564 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells.

Dhakshinamoorthy S, Porter AG.

J Biol Chem. 2004 May 7;279(19):20096-107. Epub 2004 Feb 25.PMID: 14985350 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells.

Jakubíková J, Sedlák J, Bod'o J, Bao Y.

J Agric Food Chem. 2006 Mar 8;54(5):1656-62.PMID: 16506816 [PubMed - indexed for MEDLINE]Related articles