PubMed

G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.

Trégouet DA, Groop PH, McGinn S, Forsblom C, Hadjadj S, Marre M, Parving HH, Tarnow L, Telgmann R, Godefroy T, Nicaud V, Rousseau R, Parkkonen M, Hoverfält A, Gut I, Heath S, Matsuda F, Cox R, Kazeem G, Farrall M, Gauguier D, Brand-Herrmann SM, Cambien F, Lathrop M, Vionnet N; EURAGEDIC Consortium.

Diabetes. 2008 Oct;57(10):2843-50. Epub 2008 Jul 15.PMID: 18633107 [PubMed - indexed for MEDLINE]Related articlesFree article

A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study.

Zhang D, Ma J, Brismar K, Efendic S, Gu HF.

J Diabetes Complications. 2009 Jul-Aug;23(4):265-72. Epub 2008 Jul 3.PMID: 18599322 [PubMed - indexed for MEDLINE]Related articles

Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy.

Bostrom MA, Freedman BI, Langefeld CD, Liu L, Hicks PJ, Bowden DW.

Diabetes. 2009 Feb;58(2):499-504. Epub 2008 Dec 3.PMID: 19056609 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of 14 candidate genes for diabetic nephropathy on chromosome 3q in European populations: strongest evidence for association with a variant in the promoter region of the adiponectin gene.

Vionnet N, Tregouët D, Kazeem G, Gut I, Groop PH, Tarnow L, Parving HH, Hadjadj S, Forsblom C, Farrall M, Gauguier D, Cox R, Matsuda F, Heath S, Thévard A, Rousseau R, Cambien F, Marre M, Lathrop M.

Diabetes. 2006 Nov;55(11):3166-74.PMID: 17065357 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.

Araki S, Ng DP, Krolewski B, Wyrwicz L, Rogus JJ, Canani L, Makita Y, Haneda M, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2003 Aug;14(8):2015-24.PMID: 12874455 [PubMed - indexed for MEDLINE]Related articlesFree article

The xylosyltransferase I gene polymorphism c.343G>T (p.A125S) is a risk factor for diabetic nephropathy in type 1 diabetes.

Schön S, Prante C, Bahr C, Tarnow L, Kuhn J, Kleesiek K, Götting C.

Diabetes Care. 2006 Oct;29(10):2295-9.PMID: 17003309 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. Epub 2009 Feb 27.PMID: 19252134 [PubMed - indexed for MEDLINE]Related articlesFree article

European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy.

Tarnow L, Groop PH, Hadjadj S, Kazeem G, Cambien F, Marre M, Forsblom C, Parving HH, Trégouët D, Thévard A, Farrall M, Gut I, Gauguier D, Cox R, Matsuda F, Lathrop M, Vionnet N; EURAGEDIC Consortium.

Nephrol Dial Transplant. 2008 Jan;23(1):161-8. Epub 2007 Aug 17.PMID: 17704113 [PubMed - indexed for MEDLINE]Related articles

TGF-beta 1 as a genetic susceptibility locus for advanced diabetic nephropathy in type 1 diabetes mellitus: an investigation of multiple known DNA sequence variants.

Ng DP, Warram JH, Krolewski AS.

Am J Kidney Dis. 2003 Jan;41(1):22-8.PMID: 12500218 [PubMed - indexed for MEDLINE]Related articles

Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism.

Zanchi A, Moczulski DK, Hanna LS, Wantman M, Warram JH, Krolewski AS.

Kidney Int. 2000 Feb;57(2):405-13.PMID: 10652017 [PubMed - indexed for MEDLINE]Related articlesFree article

[Polymorphism of aldose reductase gene and susceptibility to retinopathy and nephropathy in Caucasians with type 1 diabetes]

Fanelli A, Hadjadj S, Gallois Y, Fumeron F, Betoule D, Grandchamp B, Marre M.

Arch Mal Coeur Vaiss. 2002 Jul-Aug;95(7-8):701-8. French. PMID: 12365083 [PubMed - indexed for MEDLINE]Related articles

Association between variation in the actin-binding gene caldesmon and diabetic nephropathy in type 1 diabetes.

Conway BR, Maxwell AP, Savage DA, Patterson CC, Doran PP, Murphy M, Brady HR, Fogarty DG.

Diabetes. 2004 Apr;53(4):1162-5.PMID: 15047636 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.

Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI.

Diabetes. 2007 Oct;56(10):2638-42. Epub 2007 Jun 29.PMID: 17601994 [PubMed - indexed for MEDLINE]Related articlesFree article

Exclusion of polymorphisms in carnosinase genes (CNDP1 and CNDP2) as a cause of diabetic nephropathy in type 1 diabetes: results of large case-control and follow-up studies.

Wanic K, Placha G, Dunn J, Smiles A, Warram JH, Krolewski AS.

Diabetes. 2008 Sep;57(9):2547-51.PMID: 18753673 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.

Tanaka N, Babazono T, Saito S, Sekine A, Tsunoda T, Haneda M, Tanaka Y, Fujioka T, Kaku K, Kawamori R, Kikkawa R, Iwamoto Y, Nakamura Y, Maeda S.

Diabetes. 2003 Nov;52(11):2848-53.PMID: 14578305 [PubMed - indexed for MEDLINE]Related articlesFree article

Common polymorphisms of the PAI1 gene do not play a major role in the development of diabetic nephropathy in Type 1 diabetes.

Martin RJ, Savage DA, Patterson CC, Brady HR, Maxwell AP.

Diabet Med. 2007 Mar;24(3):259-65.PMID: 17263760 [PubMed - indexed for MEDLINE]Related articles

Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.

McKnight AJ, Maxwell AP, Patterson CC, Brady HR, Savage DA.

J Diabetes Complications. 2007 Jul-Aug;21(4):242-5.PMID: 17616354 [PubMed - indexed for MEDLINE]Related articles

Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians.

Ahluwalia TS, Ahuja M, Rai TS, Kohli HS, Sud K, Bhansali A, Khullar M.

Mol Cell Biochem. 2008 Jul;314(1-2):9-17. Epub 2008 Apr 10.PMID: 18401556 [PubMed - indexed for MEDLINE]Related articles

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus.

McKnight AJ, Woodman AM, Parkkonen M, Patterson CC, Savage DA, Forsblom C, Pettigrew KA, Sadlier D, Groop PH, Maxwell AP; Warren 3/UK GoKinD Study Group.

Diabetologia. 2009 May;52(5):844-9. Epub 2009 Feb 27.PMID: 19247629 [PubMed - indexed for MEDLINE]Related articles

Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics study.

Al-Kateb H, Boright AP, Mirea L, Xie X, Sutradhar R, Mowjoodi A, Bharaj B, Liu M, Bucksa JM, Arends VL, Steffes MW, Cleary PA, Sun W, Lachin JM, Thorner PS, Ho M, McKnight AJ, Maxwell AP, Savage DA, Kidd KK, Kidd JR, Speed WC, Orchard TJ, Miller RG, Sun L, Bull SB, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group.

Diabetes. 2008 Jan;57(1):218-28. Epub 2007 Oct 3.PMID: 17914031 [PubMed - indexed for MEDLINE]Related articlesFree article