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    Results: 1 to 20 of 104

    1.

    Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.

    Maile LA, Capps BE, Miller EC, Aday AW, Clemmons DR.

    Diabetes. 2008 Oct;57(10):2637-43. Epub 2008 Jul 15.PMID: 18633106 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.

    Maile LA, Capps BE, Miller EC, Allen LB, Veluvolu U, Aday AW, Clemmons DR.

    Mol Endocrinol. 2008 May;22(5):1226-37. Epub 2008 Feb 21.PMID: 18292237 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.

    Miller EC, Capps BE, Sanghani RR, Clemmons DR, Maile LA.

    Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3878-87.PMID: 17652764 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavage.

    Allen LB, Capps BE, Miller EC, Clemmons DR, Maile LA.

    Endocrinology. 2009 Mar;150(3):1321-9. Epub 2008 Oct 30.PMID: 18974270 [PubMed - indexed for MEDLINE]Related articles

    5.

    The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.

    Maile LA, Badley-Clarke J, Clemmons DR.

    Mol Biol Cell. 2003 Sep;14(9):3519-28. Epub 2003 May 29.PMID: 12972543 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.

    Ling Y, Maile LA, Lieskovska J, Badley-Clarke J, Clemmons DR.

    Mol Biol Cell. 2005 Jul;16(7):3353-64. Epub 2005 May 11.PMID: 15888547 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Integrin-associated protein binding domain of thrombospondin-1 enhances insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.

    Maile LA, Clemmons DR.

    Circ Res. 2003 Nov 14;93(10):925-31. Epub 2003 Oct 16.PMID: 14563713 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane recruitment.

    Xi G, Shen X, Clemmons DR.

    Mol Endocrinol. 2008 Sep;22(9):2162-75. Epub 2008 Jul 7.PMID: 18606861 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    The role of Src kinase in insulin-like growth factor-dependent mitogenic signaling in vascular smooth muscle cells.

    Lieskovska J, Ling Y, Badley-Clarke J, Clemmons DR.

    J Biol Chem. 2006 Sep 1;281(35):25041-53. Epub 2006 Jul 5.PMID: 16825188 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Expression of the human beta3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation.

    Xi G, Maile LA, Yoo SE, Clemmons DR.

    J Cell Physiol. 2008 Feb;214(2):306-15.PMID: 17607710 [PubMed - indexed for MEDLINE]Related articles

    11.

    Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

    Maile LA, Capps BE, Ling Y, Xi G, Clemmons DR.

    Endocrinology. 2007 May;148(5):2435-43. Epub 2007 Jan 25.PMID: 17255202 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions.

    Moralez AM, Maile LA, Clarke J, Busby WH Jr, Clemmons DR.

    J Cell Physiol. 2005 May;203(2):328-34.PMID: 15700281 [PubMed - indexed for MEDLINE]Related articles

    13.

    Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.

    Clemmons DR, Maile LA, Ling Y, Yarber J, Busby WH.

    Growth Horm IGF Res. 2007 Aug;17(4):265-70. Epub 2007 Apr 6. Review.PMID: 17412627 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.

    Radhakrishnan Y, Maile LA, Ling Y, Graves LM, Clemmons DR.

    J Biol Chem. 2008 Jun 13;283(24):16320-31. Epub 2008 Apr 16.PMID: 18420583 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.

    Sasaoka T, Kikuchi K, Wada T, Sato A, Hori H, Murakami S, Fukui K, Ishihara H, Aota R, Kimura I, Kobayashi M.

    Endocrinology. 2003 Sep;144(9):4204-14.PMID: 12933696 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor.

    Maile LA, Clemmons DR.

    Endocrinology. 2002 Nov;143(11):4259-64.PMID: 12399420 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.

    Kwon M, Ling Y, Maile LA, Badley-Clark J, Clemmons DR.

    Endocrinology. 2006 Mar;147(3):1458-65. Epub 2005 Nov 23.PMID: 16306077 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells.

    Ling Y, Maile LA, Badley-Clarke J, Clemmons DR.

    J Biol Chem. 2005 Feb 4;280(5):3151-8. Epub 2004 Nov 15.PMID: 15546884 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs.

    Clemmons DR, Maile LA.

    Mol Endocrinol. 2005 Jan;19(1):1-11. Epub 2004 Nov 4. Review.PMID: 15528274 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.

    Kobayashi M, Ohnishi H, Okazawa H, Murata Y, Hayashi Y, Kobayashi H, Kitamura T, Matozaki T.

    Endocrinology. 2008 Nov;149(11):5662-9. Epub 2008 Jul 17.PMID: 18635660 [PubMed - indexed for MEDLINE]Related articlesFree article

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