PubMed

FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.

Tan JT, Dorajoo R, Seielstad M, Sim XL, Ong RT, Chia KS, Wong TY, Saw SM, Chew SK, Aung T, Tai ES.

Diabetes. 2008 Oct;57(10):2851-7. Epub 2008 Jul 3.PMID: 18599522 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.

Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM.

Diabetes. 2008 Aug;57(8):2245-52. Epub 2008 May 16.PMID: 18487448 [PubMed - indexed for MEDLINE]Related articlesFree article

FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians.

Yajnik CS, Janipalli CS, Bhaskar S, Kulkarni SR, Freathy RM, Prakash S, Mani KR, Weedon MN, Kale SD, Deshpande J, Krishnaveni GV, Veena SR, Fall CH, McCarthy MI, Frayling TM, Hattersley AT, Chandak GR.

Diabetologia. 2009 Feb;52(2):247-52. Epub 2008 Nov 13.PMID: 19005641 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP.

Diabetes. 2009 Jun;58(6):1445-9. Epub 2009 Feb 27.PMID: 19252135 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population.

Li H, Wu Y, Loos RJ, Hu FB, Liu Y, Wang J, Yu Z, Lin X.

Diabetes. 2008 Jan;57(1):264-8. Epub 2007 Oct 24.PMID: 17959933 [PubMed - indexed for MEDLINE]Related articlesFree article

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.

Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, Lam VK, Ma RC, So WY, Cho YS, Kim HL, Lee HK, Chan JC, Cho NH.

Diabetes. 2008 Aug;57(8):2226-33. Epub 2008 May 9.PMID: 18469204 [PubMed - indexed for MEDLINE]Related articlesFree article

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population.

Qi L, Tai ES, Tan CE, Shen H, Chew SK, Greenberg AS, Corella D, Ordovas JM.

J Mol Med. 2005 Jun;83(6):448-56. Epub 2005 Mar 16.PMID: 15770500 [PubMed - indexed for MEDLINE]Related articles

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P.

J Mol Med. 2009 May;87(5):537-46. Epub 2009 Mar 3.PMID: 19255736 [PubMed - indexed for MEDLINE]Related articles

FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.

Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, F Tinker L, Liu S.

Obesity (Silver Spring). 2008 Nov;16(11):2472-80. Epub 2008 Sep 11.PMID: 18787525 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.PMID: 17658951 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.

Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2008 May;57(5):1419-26. Epub 2008 Mar 17.PMID: 18346983 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

J Clin Endocrinol Metab. 2009 Nov 5. [Epub ahead of print]PMID: 19892838 [PubMed - as supplied by publisher]Related articles

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.

Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Lindgren CM, Freathy RM, Koch K, Ouwehand WH, Karpe F, Conway GS, Wass JA, Järvelin MR, Franks S, McCarthy MI.

Diabetologia. 2008 Jul;51(7):1153-8. Epub 2008 May 14.PMID: 18478198 [PubMed - indexed for MEDLINE]Related articles

Physical activity and the association of common FTO gene variants with body mass index and obesity.

Rampersaud E, Mitchell BD, Pollin TI, Fu M, Shen H, O'Connell JR, Ducharme JL, Hines S, Sack P, Naglieri R, Shuldiner AR, Snitker S.

Arch Intern Med. 2008 Sep 8;168(16):1791-7. Erratum in: Arch Intern Med. 2009 Mar 9;169(5):453. PMID: 18779467 [PubMed - indexed for MEDLINE]Related articlesFree article

FTO polymorphisms in oceanic populations.

Ohashi J, Naka I, Kimura R, Natsuhara K, Yamauchi T, Furusawa T, Nakazawa M, Ataka Y, Patarapotikul J, Nuchnoi P, Tokunaga K, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R.

J Hum Genet. 2007;52(12):1031-5. Epub 2007 Oct 11.PMID: 17928949 [PubMed - indexed for MEDLINE]Related articles

Variations in the FTO gene are associated with severe obesity in the Japanese.

Hotta K, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y.

J Hum Genet. 2008;53(6):546-53. Epub 2008 Apr 1.PMID: 18379722 [PubMed - indexed for MEDLINE]Related articlesFree article

APOE polymorphism and lipid profile in three ethnic groups in the Singapore population.

Tan CE, Tai ES, Tan CS, Chia KS, Lee J, Chew SK, Ordovas JM.

Atherosclerosis. 2003 Oct;170(2):253-60.PMID: 14612205 [PubMed - indexed for MEDLINE]Related articles

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.

Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbaek A, Lauritzen T, Hansen L, Jørgensen T, Pedersen O, Hansen T.

Diabetes. 2008 Jan;57(1):95-101. Epub 2007 Oct 17.PMID: 17942823 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

Grant SF, Li M, Bradfield JP, Kim CE, Annaiah K, Santa E, Glessner JT, Casalunovo T, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Imielinski M, Eckert AW, Chiavacci RM, Berkowitz RI, Hakonarson H.

PLoS One. 2008 Mar 12;3(3):e1746.PMID: 18335027 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethnic differences among Chinese, Malay and Indian patients with type 2 diabetes mellitus in Singapore.

Hong CY, Chia KS, Hughes K, Ling SL.

Singapore Med J. 2004 Apr;45(4):154-60.PMID: 15094983 [PubMed - indexed for MEDLINE]Related articlesFree article