PubMed

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR.

Diabetes. 2008 Nov;57(11):3034-44. Epub 2008 Jun 30.PMID: 18591394 [PubMed - indexed for MEDLINE]Related articlesFree article

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells.

Sargsyan E, Ortsäter H, Thorn K, Bergsten P.

J Endocrinol. 2008 Oct;199(1):41-50. Epub 2008 Jul 21.PMID: 18644846 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids.

Diakogiannaki E, Welters HJ, Morgan NG.

J Endocrinol. 2008 Jun;197(3):553-63.PMID: 18492819 [PubMed - indexed for MEDLINE]Related articlesFree article

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

Cardozo AK, Ortis F, Storling J, Feng YM, Rasschaert J, Tonnesen M, Van Eylen F, Mandrup-Poulsen T, Herchuelz A, Eizirik DL.

Diabetes. 2005 Feb;54(2):452-61.PMID: 15677503 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.PMID: 17268797 [PubMed - indexed for MEDLINE]Related articles

IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway.

Wang Q, Zhang H, Zhao B, Fei H.

Mol Cell Biochem. 2009 Apr;324(1-2):183-90. Epub 2008 Dec 25.PMID: 19109696 [PubMed - indexed for MEDLINE]Related articles

Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.

Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL, Cardozo AK.

Diabetes. 2007 Apr;56(4):1069-77.PMID: 17395747 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis.

Karaskov E, Scott C, Zhang L, Teodoro T, Ravazzola M, Volchuk A.

Endocrinology. 2006 Jul;147(7):3398-407. Epub 2006 Apr 6.PMID: 16601139 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.

Bachar E, Ariav Y, Ketzinel-Gilad M, Cerasi E, Kaiser N, Leibowitz G.

PLoS One. 2009;4(3):e4954. Epub 2009 Mar 23.PMID: 19305497 [PubMed - indexed for MEDLINE]Related articlesFree article

Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.

Yokouchi M, Hiramatsu N, Hayakawa K, Kasai A, Takano Y, Yao J, Kitamura M.

Cell Death Differ. 2007 Aug;14(8):1467-74. Epub 2007 Apr 27.PMID: 17464326 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2008 Apr;57(4):846-59. Epub 2008 Jan 3.PMID: 18174526 [PubMed - indexed for MEDLINE]Related articlesFree article

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers.

Li F, Hayashi T, Jin G, Deguchi K, Nagotani S, Nagano I, Shoji M, Chan PH, Abe K.

Brain Res. 2005 Jun 28;1048(1-2):59-68.PMID: 15921666 [PubMed - indexed for MEDLINE]Related articles

Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress.

Kim KM, Pae HO, Zheng M, Park R, Kim YM, Chung HT.

Circ Res. 2007 Oct 26;101(9):919-27. Epub 2007 Sep 6.PMID: 17823375 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of double-stranded RNA-dependent protein kinase in ER stress-induced retinal neuron damage.

Shimazawa M, Ito Y, Inokuchi Y, Hara H.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3729-36.PMID: 17652745 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.PMID: 12446838 [PubMed - indexed for MEDLINE]Related articlesFree article

Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.

Han MS, Chung KW, Cheon HG, Rhee SD, Yoon CH, Lee MK, Kim KW, Lee MS.

Diabetes. 2009 Feb;58(2):329-36.PMID: 19171749 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition.

Fu HY, Minamino T, Tsukamoto O, Sawada T, Asai M, Kato H, Asano Y, Fujita M, Takashima S, Hori M, Kitakaze M.

Cardiovasc Res. 2008 Sep 1;79(4):600-10. Epub 2008 May 28.PMID: 18508854 [PubMed - indexed for MEDLINE]Related articlesFree article

Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.

Tsutsumi S, Namba T, Tanaka KI, Arai Y, Ishihara T, Aburaya M, Mima S, Hoshino T, Mizushima T.

Oncogene. 2006 Feb 16;25(7):1018-29.PMID: 16205636 [PubMed - indexed for MEDLINE]Related articles