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    Results: 1 to 20 of 134

    1.

    Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice.

    Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Kawaguchi M, Terao M, Doi R, Wright CV, Hoshino M, Chiba T, Uemoto S.

    Diabetes. 2008 Sep;57(9):2421-31. Epub 2008 Jun 30.PMID: 18591390 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish.

    Jiang Z, Song J, Qi F, Xiao A, An X, Liu NA, Zhu Z, Zhang B, Lin S.

    PLoS Biol. 2008 Nov 25;6(11):e293.PMID: 19067490 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.

    Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, Kageyama R, Wright CV, Chiba T.

    J Clin Invest. 2006 Jun;116(6):1484-93. Epub 2006 May 18.PMID: 16710472 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.

    Burlison JS, Long Q, Fujitani Y, Wright CV, Magnuson MA.

    Dev Biol. 2008 Apr 1;316(1):74-86. Epub 2008 Jan 26.PMID: 18294628 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.

    Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV.

    Nat Genet. 2002 Sep;32(1):128-34. Epub 2002 Aug 19.PMID: 12185368 [PubMed - indexed for MEDLINE]Related articles

    6.

    The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

    Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

    J Clin Invest. 2009 Jul;119(7):1888-98.PMID: 19487809 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.

    McKinnon CM, Docherty K.

    Diabetologia. 2001 Oct;44(10):1203-14. Review.PMID: 11692168 [PubMed - indexed for MEDLINE]Related articles

    8.

    Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.

    Gannon M, Ray MK, Van Zee K, Rausa F, Costa RH, Wright CV.

    Development. 2000 Jul;127(13):2883-95.PMID: 10851133 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation.

    Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M.

    Dev Biol. 2008 Nov 1;323(1):19-30. Epub 2008 Aug 6.PMID: 18723011 [PubMed - indexed for MEDLINE]Related articles

    10.

    Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas.

    Dong PD, Provost E, Leach SD, Stainier DY.

    Genes Dev. 2008 Jun 1;22(11):1445-50.PMID: 18519637 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

    Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV.

    Dev Biol. 2008 Feb 15;314(2):406-17. Epub 2007 Nov 4.PMID: 18155690 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.

    Gannon M, Gamer LW, Wright CV.

    Dev Biol. 2001 Oct 1;238(1):185-201.PMID: 11784003 [PubMed - indexed for MEDLINE]Related articles

    14.

    Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development.

    Hald J, Sprinkel AE, Ray M, Serup P, Wright C, Madsen OD.

    J Histochem Cytochem. 2008 Jun;56(6):587-95. Epub 2008 Mar 17.PMID: 18347078 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors.

    Wilding L, Gannon M.

    Diabetes Metab Res Rev. 2004 Mar-Apr;20(2):114-23. Review.PMID: 15037986 [PubMed - indexed for MEDLINE]Related articles

    16.

    Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.

    Wiebe PO, Kormish JD, Roper VT, Fujitani Y, Alston NI, Zaret KS, Wright CV, Stein RW, Gannon M.

    Mol Cell Biol. 2007 Jun;27(11):4093-104. Epub 2007 Apr 2.PMID: 17403901 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.

    Nelson SB, Schaffer AE, Sander M.

    Development. 2007 Jul;134(13):2491-500. Epub 2007 May 30.PMID: 17537793 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    A multipotent progenitor domain guides pancreatic organogenesis.

    Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA.

    Dev Cell. 2007 Jul;13(1):103-14.PMID: 17609113 [PubMed - indexed for MEDLINE]Related articles

    19.

    Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development.

    Fujikura J, Hosoda K, Kawaguchi Y, Noguchi M, Iwakura H, Odori S, Mori E, Tomita T, Hirata M, Ebihara K, Masuzaki H, Fukuda A, Furuyama K, Tanigaki K, Yabe D, Nakao K.

    Dev Dyn. 2007 Oct;236(10):2779-91.PMID: 17849436 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III.

    Miyatsuka T, Matsuoka TA, Shiraiwa T, Yamamoto T, Kojima I, Kaneto H.

    Biochem Biophys Res Commun. 2007 Nov 3;362(4):905-9. Epub 2007 Aug 24.PMID: 17803961 [PubMed - indexed for MEDLINE]Related articles

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