PubMed

A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes.

Wenzlau JM, Liu Y, Yu L, Moua O, Fowler KT, Rangasamy S, Walters J, Eisenbarth GS, Davidson HW, Hutton JC.

Diabetes. 2008 Oct;57(10):2693-7. Epub 2008 Jun 30.PMID: 18591387 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes.

Kawasaki E, Uga M, Nakamura K, Kuriya G, Satoh T, Fujishima K, Ozaki M, Abiru N, Yamasaki H, Wenzlau JM, Davidson HW, Hutton JC, Eguchi K.

Diabetologia. 2008 Dec;51(12):2299-302. Epub 2008 Oct 11.PMID: 18850084 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk.

Achenbach P, Lampasona V, Landherr U, Koczwara K, Krause S, Grallert H, Winkler C, Pflüger M, Illig T, Bonifacio E, Ziegler AG.

Diabetologia. 2009 Sep;52(9):1881-8. Epub 2009 Jul 10.PMID: 19590848 [PubMed - in process]Related articles

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.

Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, Gottlieb P, Rewers M, Eisenbarth GS, Jensen J, Davidson HW, Hutton JC.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17040-5. Epub 2007 Oct 17.PMID: 17942684 [PubMed - indexed for MEDLINE]Related articlesFree article

New antigenic targets in type 1 diabetes.

Wenzlau JM, Hutton JC, Davidson HW.

Curr Opin Endocrinol Diabetes Obes. 2008 Aug;15(4):315-20. Review.PMID: 18594270 [PubMed - indexed for MEDLINE]Related articles

Cytotoxic T lymphocyte antigen 4 gene polymorphism confers susceptibility to type 1 diabetes in Japanese children: analysis of association with HLA genotypes and autoantibodies.

Kikuoka N, Sugihara S, Yanagawa T, Ikezaki A, Kim HS, Matsuoka H, Kobayashi Y, Wataki K, Konda S, Sato H, Miyamoto S, Sasaki N, Sakamaki T, Niimi H, Murata M.

Clin Endocrinol (Oxf). 2001 Nov;55(5):597-603.PMID: 11894970 [PubMed - indexed for MEDLINE]Related articles

SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes.

Wenzlau JM, Moua O, Sarkar SA, Yu L, Rewers M, Eisenbarth GS, Davidson HW, Hutton JC.

Ann N Y Acad Sci. 2008 Dec;1150:256-9.PMID: 19120307 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes.

Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith G.

J Clin Endocrinol Metab. 2009 Feb;94(2):504-10. Epub 2008 Dec 2.PMID: 19050058 [PubMed - indexed for MEDLINE]Related articles

Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?

Tiberti C, Buzzetti R, Anastasi E, Dotta F, Vasta M, Petrone A, Cervoni M, Torresi P, Vecci E, Multari G, Di Mario U.

Diabetes Metab Res Rev. 2000 Jan-Feb;16(1):8-14.PMID: 10707033 [PubMed - indexed for MEDLINE]Related articles

SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset.

Gohlke H, Ferrari U, Koczwara K, Bonifacio E, Illig T, Ziegler AG.

Rev Diabet Stud. 2008 Spring;5(1):25-7. Epub 2008 May 10.PMID: 18548167 [PubMed - in process]Related articlesFree article

Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese.

Xiang J, Li XY, Xu M, Hong J, Huang Y, Tan JR, Lu X, Dai M, Yu B, Ning G.

J Clin Endocrinol Metab. 2008 Oct;93(10):4107-12. Epub 2008 Jul 15.PMID: 18628523 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. Epub 2009 Jun 19.PMID: 19542200 [PubMed - indexed for MEDLINE]Related articles

Identification of a major humoral epitope in Slc30A8 (ZnT8).

Wenzlau JM, Moua O, Liu Y, Eisenbarth GS, Hutton JC, Davidson HW.

Ann N Y Acad Sci. 2008 Dec;1150:252-5.PMID: 19120306 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the zinc transporter gene SLC30A8 confers resistance against posttransplantation diabetes mellitus in renal allograft recipients.

Kang ES, Kim MS, Kim YS, Kim CH, Han SJ, Chun SW, Hur KY, Nam CM, Ahn CW, Cha BS, Kim SI, Lee HC.

Diabetes. 2008 Apr;57(4):1043-7. Epub 2007 Dec 27.PMID: 18162509 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of hypoxia inducible factor-1 alpha gene polymorphism with both type 1 and type 2 diabetes in a Caucasian (Hungarian) sample.

Nagy G, Kovacs-Nagy R, Kereszturi E, Somogyi A, Szekely A, Nemeth N, Hosszufalusi N, Panczel P, Ronai Z, Sasvari-Szekely M.

BMC Med Genet. 2009 Aug 19;10:79.PMID: 19691832 [PubMed - indexed for MEDLINE]Related articlesFree article

The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.

Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C, Cossu E, Pozzilli P, Falorni A, Buzzetti R; NIRAD Study Group.

Diabetes Care. 2008 Mar;31(3):534-8. Epub 2007 Dec 4.PMID: 18056891 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between IA-2 autoantibody epitope specificities and age of onset in Japanese patients with autoimmune diabetes.

Kawasaki E, Sera Y, Fujita N, Yamauchi M, Ozaki M, Abe T, Yamakawa K, Uotani S, Takino H, Yamasaki H, Yamaguchi Y, Uchigata Y, Matsuura N, Eguchi K.

J Autoimmun. 2001 Dec;17(4):323-31.PMID: 11771957 [PubMed - indexed for MEDLINE]Related articles

IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.

Shin JH, Janer M, McNeney B, Blay S, Deutsch K, Sanjeevi CB, Kockum I, Lernmark A, Graham J; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group, Arnqvist H, Björck E, Eriksson J, Nyström L, Ohlson LO, Scherstén B, Ostman J, Aili M, Bååth LE, Carlsson E, Edenwall H, Forsander G, Granström BW, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson SA, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Aman J.

Genes Immun. 2007 Sep;8(6):503-12. Epub 2007 Jul 19.PMID: 17641683 [PubMed - indexed for MEDLINE]Related articles

PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.

Smyth DJ, Cooper JD, Howson JM, Walker NM, Plagnol V, Stevens H, Clayton DG, Todd JA.

Diabetes. 2008 Jun;57(6):1730-7. Epub 2008 Feb 27.PMID: 18305142 [PubMed - indexed for MEDLINE]Related articlesFree article