PubMed

UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.

Dec Bronsvoort BM, Makepeace BL, Renz A, Tanya VN, Fleckenstein L, Ekale D, Trees AJ.

Parasit Vectors. 2008 Jun 20;1(1):18.PMID: 18570639 [PubMed - in process]Related articlesFree article

Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle.

Bronsvoort BM, Renz A, Tchakouté V, Tanya VN, Ekale D, Trees AJ.

Filaria J. 2005 Aug 8;4:8.PMID: 16086838 [PubMed]Related articlesFree article

Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship.

Langworthy NG, Renz A, Mackenstedt U, Henkle-Dührsen K, de Bronsvoort MB, Tanya VN, Donnelly MJ, Trees AJ.

Proc Biol Sci. 2000 Jun 7;267(1448):1063-9.PMID: 10885510 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of suramin, ivermectin and CGP 20376 in a new macrofilaricidal drug screen, Onchocerca ochengi in African cattle.

Renz A, Trees AJ, Achu-Kwi D, Edwards G, Wahl G.

Trop Med Parasitol. 1995 Mar;46(1):31-7.PMID: 7631125 [PubMed - indexed for MEDLINE]Related articles

Onchocerca ochengi infections in cattle as a model for human onchocerciasis: recent developments.

Trees AJ, Graham SP, Renz A, Bianco AE, Tanya V.

Parasitology. 2000;120 Suppl:S133-42. Review.PMID: 10874716 [PubMed - indexed for MEDLINE]Related articles

Chemoprophylaxis of Onchocerca infections: in a controlled, prospective study ivermectin prevents calves becoming infected with O. ochengi.

Tchakouté VL, Bronsvoort M, Tanya V, Renz A, Trees AJ.

Parasitology. 1999 Feb;118 ( Pt 2):195-9.PMID: 10028534 [PubMed - indexed for MEDLINE]Related articles

Evidence for macrofilaricidal activity of ivermectin against female Onchocerca volvulus: further analysis of a clinical trial in the Republic of Cameroon indicating two distinct killing mechanisms.

Duke BO.

Parasitology. 2005 Apr;130(Pt 4):447-53.PMID: 15830819 [PubMed - indexed for MEDLINE]Related articles

Eosinophils contribute to killing of adult Onchocerca ochengi within onchocercomata following elimination of Wolbachia.

Nfon CK, Makepeace BL, Njongmeta LM, Tanya VN, Bain O, Trees AJ.

Microbes Infect. 2006 Oct;8(12-13):2698-705. Epub 2006 Aug 22.PMID: 16962357 [PubMed - indexed for MEDLINE]Related articles

Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi.

Townson S, Hutton D, Siemienska J, Hollick L, Scanlon T, Tagboto SK, Taylor MJ.

Ann Trop Med Parasitol. 2000 Dec;94(8):801-16.PMID: 11214099 [PubMed - indexed for MEDLINE]Related articles

Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin.

Debrah AY, Mand S, Marfo-Debrekyei Y, Larbi J, Adjei O, Hoerauf A.

Filaria J. 2006 Feb 5;5:1.PMID: 16457735 [PubMed]Related articlesFree article

The entry of ivermectin and suramin into Onchocerca ochengi nodules.

Cross HF, Bronsvoort BM, Wahl G, Renz A, Achu-Kwi D, Trees AJ.

Ann Trop Med Parasitol. 1997 Jun;91(4):393-401.PMID: 9290846 [PubMed - indexed for MEDLINE]Related articles

Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro.

Townson S, Tagboto S, McGarry HF, Egerton GL, Taylor MJ.

Filaria J. 2006 Mar 24;5:4.PMID: 16563157 [PubMed]Related articlesFree article

In-vitro uptake of ivermectin by adult male Onchocerca ochengi.

Cross HF, Renz A, Trees AJ.

Ann Trop Med Parasitol. 1998 Sep;92(6):711-20.PMID: 9924550 [PubMed - indexed for MEDLINE]Related articles

The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients.

Awadzi K, Attah SK, Addy ET, Opoku NO, Quartey BT.

Trans R Soc Trop Med Hyg. 1999 Mar-Apr;93(2):189-94.PMID: 10450448 [PubMed - indexed for MEDLINE]Related articles

In vitro assessment of the activity of anthelmintic compounds on adults of Onchocerca volvulus.

Strote G, Wieland S, Darge K, Comley JC.

Acta Leiden. 1990;59(1-2):285-96.PMID: 2378212 [PubMed - indexed for MEDLINE]Related articles

The effects of ivermectin used in combination with other known antiparasitic drugs on adult Onchocerca gutturosa and O. volvulus in vitro.

Townson S, Dobinson AR, Townsend J, Siemienska J, Zea-Flores G.

Trans R Soc Trop Med Hyg. 1990 May-Jun;84(3):411-6.PMID: 2260177 [PubMed - indexed for MEDLINE]Related articles

Efficacy of 2- and 4-week rifampicin treatment on the Wolbachia of Onchocerca volvulus.

Specht S, Mand S, Marfo-Debrekyei Y, Debrah AY, Konadu P, Adjei O, Büttner DW, Hoerauf A.

Parasitol Res. 2008 Nov;103(6):1303-9. Epub 2008 Aug 5.PMID: 18679718 [PubMed - indexed for MEDLINE]Related articles

Drug activity against Onchocerca gutturosa males in vitro: a model for chemotherapeutic research on onchocerciasis.

Townson S, Connelly C, Dobinson A, Muller R.

J Helminthol. 1987 Dec;61(4):271-81.PMID: 3437107 [PubMed - indexed for MEDLINE]Related articles

Antibiotic chemotherapy of onchocerciasis: in a bovine model, killing of adult parasites requires a sustained depletion of endosymbiotic bacteria (Wolbachia species).

Gilbert J, Nfon CK, Makepeace BL, Njongmeta LM, Hastings IM, Pfarr KM, Renz A, Tanya VN, Trees AJ.

J Infect Dis. 2005 Oct 15;192(8):1483-93. Epub 2005 Sep 14.PMID: 16170768 [PubMed - indexed for MEDLINE]Related articles

A preliminary assessment of the feasibility of evaluating promising antifilarials in vitro against adult Onchocerca volvulus.

Comley JC, Szopa TM, Strote G, Buttner M, Darge K, Buttner DW.

Parasitology. 1989 Dec;99 Pt 3:417-25.PMID: 2558338 [PubMed - indexed for MEDLINE]Related articles