PubMed

Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.

Vacca RA, Giannattasio S, Capitani G, Marra E, Christen P.

BMC Biochem. 2008 Jun 19;9:17.PMID: 18565210 [PubMed - indexed for MEDLINE]Related articlesFree article

Pyridoxal-5'-phosphate-dependent catalytic antibodies.

Gramatikova S, Mouratou B, Stetefeld J, Mehta PK, Christen P.

J Immunol Methods. 2002 Nov 1;269(1-2):99-110. Review.PMID: 12379355 [PubMed - indexed for MEDLINE]Related articles

The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes.

Mehta PK, Christen P.

Adv Enzymol Relat Areas Mol Biol. 2000;74:129-84. Review.PMID: 10800595 [PubMed - indexed for MEDLINE]Related articles

Monoclonal antibodies against Nalpha-(5'-phosphopyridoxyl)-L-lysine. Screening and spectrum of pyridoxal 5'-phosphate-dependent activities toward amino acids.

Gramatikova SI, Christen P.

J Biol Chem. 1997 Apr 11;272(15):9779-84.PMID: 9092511 [PubMed - indexed for MEDLINE]Related articlesFree article

A change in the internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transimination and as a general base catalyst.

Rege VD, Kredich NM, Tai CH, Karsten WE, Schnackerz KD, Cook PF.

Biochemistry. 1996 Oct 15;35(41):13485-93.PMID: 8873618 [PubMed - indexed for MEDLINE]Related articles

Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphate.

Yano T, Kuramitsu S, Tanase S, Morino Y, Kagamiyama H.

Biochemistry. 1992 Jun 30;31(25):5878-87.PMID: 1610831 [PubMed - indexed for MEDLINE]Related articles

Identification of lysine 346 as a functionally important residue for pyridoxal 5'-phosphate binding and catalysis in lysine 2, 3-aminomutase from Bacillus subtilis.

Chen D, Frey PA.

Biochemistry. 2001 Jan 16;40(2):596-602.PMID: 11148055 [PubMed - indexed for MEDLINE]Related articles

Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.

Sivaraman J, Li Y, Larocque R, Schrag JD, Cygler M, Matte A.

J Mol Biol. 2001 Aug 24;311(4):761-76.PMID: 11518529 [PubMed - indexed for MEDLINE]Related articles

Effects of the E177K mutation in D-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity.

van Ophem PW, Peisach D, Erickson SD, Soda K, Ringe D, Manning JM.

Biochemistry. 1999 Jan 26;38(4):1323-31.PMID: 9930994 [PubMed - indexed for MEDLINE]Related articles

Stereospecificity for the hydrogen transfer and molecular evolution of pyridoxal enzymes.

Yoshimura T, Jhee KH, Soda K.

Biosci Biotechnol Biochem. 1996 Feb;60(2):181-7. Review.PMID: 9063963 [PubMed - indexed for MEDLINE]Related articles

Coulombic forces in protein-RNA interactions: binding and cleavage by ribonuclease A and variants at Lys7, Arg10, and Lys66.

Fisher BM, Ha JH, Raines RT.

Biochemistry. 1998 Sep 1;37(35):12121-32.PMID: 9724524 [PubMed - indexed for MEDLINE]Related articles

From cofactor to enzymes. The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes.

Christen P, Mehta PK.

Chem Rec. 2001;1(6):436-47. Review.PMID: 11933250 [PubMed - indexed for MEDLINE]Related articles

Lysine-69 plays a key role in catalysis by ornithine decarboxylase through acceleration of the Schiff base formation, decarboxylation, and product release steps.

Osterman AL, Brooks HB, Jackson L, Abbott JJ, Phillips MA.

Biochemistry. 1999 Sep 7;38(36):11814-26.PMID: 10512638 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel pyridoxal 5'-phosphate binding site in adenosylcobalamin-dependent lysine 5,6-aminomutase from Porphyromonas gingivalis.

Tang KH, Harms A, Frey PA.

Biochemistry. 2002 Jul 9;41(27):8767-76.PMID: 12093296 [PubMed - indexed for MEDLINE]Related articles

Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase. Effects of exogenous amines on the slow formation of intermediates.

Futaki S, Ueno H, Martinez del Pozo A, Pospischil MA, Manning JM, Ringe D, Stoddard B, Tanizawa K, Yoshimura T, Soda K.

J Biol Chem. 1990 Dec 25;265(36):22306-12.PMID: 2125047 [PubMed - indexed for MEDLINE]Related articlesFree article

Visualization of PLP-bound intermediates in hemeless variants of human cystathionine beta-synthase: evidence that lysine 119 is a general base.

Evande R, Ojha S, Banerjee R.

Arch Biochem Biophys. 2004 Jul 15;427(2):188-96.PMID: 15196993 [PubMed - indexed for MEDLINE]Related articles

Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.

Bhavani S, Trivedi V, Jala VR, Subramanya HS, Kaul P, Prakash V, Appaji Rao N, Savithri HS.

Biochemistry. 2005 May 10;44(18):6929-37.PMID: 15865438 [PubMed - indexed for MEDLINE]Related articles

Identification of functionally important residues in the pyridoxal-5'-phosphate-dependent catalytic antibody 15A9.

Mouratou B, Stetefeld J.

Biochemistry. 2004 Jun 1;43(21):6612-9.PMID: 15157094 [PubMed - indexed for MEDLINE]Related articles

Pyridoxal-5'-phosphate-dependent catalytic antibodies.

Gramatikova SI, Christen P.

Appl Biochem Biotechnol. 2000 Jan-Mar;83(1-3):183-90; discussion 190-3, 297-313.PMID: 10826959 [PubMed - indexed for MEDLINE]Related articles

Aspartate-279 in aminolevulinate synthase affects enzyme catalysis through enhancing the function of the pyridoxal 5'-phosphate cofactor.

Gong J, Hunter GA, Ferreira GC.

Biochemistry. 1998 Mar 10;37(10):3509-17.PMID: 9521672 [PubMed - indexed for MEDLINE]Related articles