PubMed

Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction.

Haug KB, Sharikabad MN, Kringen MK, Narum S, Sjaatil ST, Johansen PW, Kierulf P, Seljeflot I, Arnesen H, Brørs O.

Thromb J. 2008 Jun 17;6:7.PMID: 18559094 [PubMed - in process]Related articlesFree article

Effect of CYP2C9 and VKORC1 genotypes on early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement.

Kim HS, Lee SS, Oh M, Jang YJ, Kim EY, Han IY, Cho KH, Shin JG.

Pharmacogenet Genomics. 2009 Feb;19(2):103-12.PMID: 19077919 [PubMed - indexed for MEDLINE]Related articles

Genotypes of the cytochrome p450 isoform, CYP2C9, and the vitamin K epoxide reductase complex subunit 1 conjointly determine stable warfarin dose: a prospective study.

Carlquist JF, Horne BD, Muhlestein JB, Lappé DL, Whiting BM, Kolek MJ, Clarke JL, James BC, Anderson JL.

J Thromb Thrombolysis. 2006 Dec;22(3):191-7.PMID: 17111199 [PubMed - indexed for MEDLINE]Related articles

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.

Takahashi H, Wilkinson GR, Nutescu EA, Morita T, Ritchie MD, Scordo MG, Pengo V, Barban M, Padrini R, Ieiri I, Otsubo K, Kashima T, Kimura S, Kijima S, Echizen H.

Pharmacogenet Genomics. 2006 Feb;16(2):101-10.PMID: 16424822 [PubMed - indexed for MEDLINE]Related articles

Contribution of age, body weight, and CYP2C9 and VKORC1 genotype to the anticoagulant response to warfarin: proposal for a new dosing regimen in Chinese patients.

Miao L, Yang J, Huang C, Shen Z.

Eur J Clin Pharmacol. 2007 Dec;63(12):1135-41. Epub 2007 Sep 27.PMID: 17899045 [PubMed - indexed for MEDLINE]Related articles

Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.

Li C, Schwarz UI, Ritchie MD, Roden DM, Stein CM, Kurnik D.

Blood. 2009 Apr 23;113(17):3925-30. Epub 2008 Dec 12.PMID: 19074728 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of CYP2C9 and VKORC1 on warfarin response during initiation of therapy.

Limdi NA, Wiener H, Goldstein JA, Acton RT, Beasley TM.

Blood Cells Mol Dis. 2009 Jul-Aug;43(1):119-28. Epub 2009 Mar 17.PMID: 19297219 [PubMed - indexed for MEDLINE]Related articles

Factors affecting the interindividual variability of warfarin dose requirement in adult Korean patients.

Cho HJ, Sohn KH, Park HM, Lee KH, Choi B, Kim S, Kim JS, On YK, Chun MR, Kim HJ, Kim JW, Lee SY.

Pharmacogenomics. 2007 Apr;8(4):329-37.PMID: 17391071 [PubMed - indexed for MEDLINE]Related articles

Genetic determinants of response to warfarin during initial anticoagulation.

Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM.

N Engl J Med. 2008 Mar 6;358(10):999-1008.PMID: 18322281 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimation of warfarin maintenance dose based on VKORC1 (-1639 G>A) and CYP2C9 genotypes.

Zhu Y, Shennan M, Reynolds KK, Johnson NA, Herrnberger MR, Valdes R Jr, Linder MW.

Clin Chem. 2007 Jul;53(7):1199-205. Epub 2007 May 17.PMID: 17510308 [PubMed - indexed for MEDLINE]Related articlesFree article

An analysis of the relative effects of VKORC1 and CYP2C9 variants on anticoagulation related outcomes in warfarin-treated patients.

Meckley LM, Wittkowsky AK, Rieder MJ, Rettie AE, Veenstra DL.

Thromb Haemost. 2008 Aug;100(2):229-39.PMID: 18690342 [PubMed - indexed for MEDLINE]Related articles

[Association between CYP2C9 and VKORC1 genetic polymorphism and warfarin dose requirements]

Yang J, Miao LY, Huang CR, Shen ZY, Jiang WP.

Zhonghua Xin Xue Guan Bing Za Zhi. 2008 Feb;36(2):137-40. Chinese. PMID: 19099951 [PubMed - indexed for MEDLINE]Related articles

VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.

Obayashi K, Nakamura K, Kawana J, Ogata H, Hanada K, Kurabayashi M, Hasegawa A, Yamamoto K, Horiuchi R.

Clin Pharmacol Ther. 2006 Aug;80(2):169-78.PMID: 16890578 [PubMed - indexed for MEDLINE]Related articles

Allelic variants in the CYP2C9 and VKORC1 loci and interindividual variability in the anticoagulant dose effect of warfarin in Italians.

Borgiani P, Ciccacci C, Forte V, Romano S, Federici G, Novelli G.

Pharmacogenomics. 2007 Nov;8(11):1545-50.PMID: 18034619 [PubMed - indexed for MEDLINE]Related articles

Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans.

Limdi NA, Arnett DK, Goldstein JA, Beasley TM, McGwin G, Adler BK, Acton RT.

Pharmacogenomics. 2008 May;9(5):511-26.PMID: 18466099 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation.

Li T, Lange LA, Li X, Susswein L, Bryant B, Malone R, Lange EM, Huang TY, Stafford DW, Evans JP.

J Med Genet. 2006 Sep;43(9):740-4. Epub 2006 Apr 12.PMID: 16611750 [PubMed - indexed for MEDLINE]Related articlesFree article

Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.

Scott SA, Edelmann L, Kornreich R, Desnick RJ.

Am J Hum Genet. 2008 Feb;82(2):495-500. Epub 2008 Jan 17.PMID: 18252229 [PubMed - indexed for MEDLINE]Related articlesFree article

VKORC1 and CYP2C9 genotypes and acenocoumarol anticoagulation status: interaction between both genotypes affects overanticoagulation.

Schalekamp T, Brassé BP, Roijers JF, Chahid Y, van Geest-Daalderop JH, de Vries-Goldschmeding H, van Wijk EM, Egberts AC, de Boer A.

Clin Pharmacol Ther. 2006 Jul;80(1):13-22.PMID: 16815313 [PubMed - indexed for MEDLINE]Related articles

Prevalence of CYP2C9 and VKORC1 mutation in patients with valvular heart disease in northern Thailand.

Kuanprasert S, Dettrairat S, Palacajornsuk P, Kunachiwa W, Phrommintikul A.

J Med Assoc Thai. 2009 Dec;92(12):1597-601.PMID: 20043560 [PubMed - in process]Related articles

Plasma S/R ratio of warfarin co-varies with VKORC1 haplotype.

Osman A, Enström C, Lindahl TL.

Blood Coagul Fibrinolysis. 2007 Apr;18(3):293-6.PMID: 17413769 [PubMed - indexed for MEDLINE]Related articles