PubMed

Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).

Butty V, Campbell C, Mathis D, Benoist C; DPT-1 Study Group.

Diabetes. 2008 Sep;57(9):2348-59. Epub 2008 Jun 12.PMID: 18556337 [PubMed - indexed for MEDLINE]Related articlesFree article

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

Steck AK, Zhang W, Bugawan TL, Barriga KJ, Blair A, Erlich HA, Eisenbarth GS, Norris JM, Rewers MJ.

Diabetes. 2009 Apr;58(4):1028-33. Epub 2009 Feb 2.PMID: 19188433 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes.

Hermann R, Lipponen K, Kiviniemi M, Kakko T, Veijola R, Simell O, Knip M, Ilonen J.

Diabetologia. 2006 Jun;49(6):1198-208. Epub 2006 Apr 14.PMID: 16614815 [PubMed - indexed for MEDLINE]Related articles

Progression to insulin-requiring diabetes in seronegative prediabetic subjects: the role of two HLA-DQ high-risk haplotypes.

Pietropaolo M, Becker DJ, LaPorte RE, Dorman JS, Riboni S, Rudert WA, Mazumdar S, Trucco M.

Diabetologia. 2002 Jan;45(1):66-76.PMID: 11845225 [PubMed - indexed for MEDLINE]Related articles

HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients.

Cejkova P, Novota P, Cerna M, Kolostova K, Novakova D, Kucera P, Novak J, Andel M, Weber P, Zdarsky E.

Int J Immunogenet. 2008 Apr;35(2):133-40. Epub 2008 Feb 11.PMID: 18279373 [PubMed - indexed for MEDLINE]Related articles

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA.

N Engl J Med. 2008 Dec 25;359(26):2767-77. Epub 2008 Dec 10.PMID: 19073967 [PubMed - indexed for MEDLINE]Related articlesFree article

Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes.

Bjørnvold M, Undlien DE, Joner G, Dahl-Jørgensen K, Njølstad PR, Akselsen HE, Gervin K, Rønningen KS, Stene LC.

Diabetologia. 2008 Apr;51(4):589-96. Epub 2008 Feb 22.PMID: 18292987 [PubMed - indexed for MEDLINE]Related articlesFree article

Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group.

Sabbah E, Savola K, Kulmala P, Reijonen H, Veijola R, Vähäsalo P, Karjalainen J, Ilonen J, Akerblom HK, Knip M.

Clin Exp Immunol. 1999 Apr;116(1):78-83.PMID: 10209508 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-DQB1 genotypes and islet cell antibodies in the identification of siblings at risk for insulin-dependent diabetes (IDDM) in Finland. Childhood Diabetes in Finland (DiMe) Study Group.

Reijonen H, Vähäsalo P, Karjalainen J, Ilonen J, Akerblom HK, Knip M.

J Autoimmun. 1994 Oct;7(5):675-86.PMID: 7840859 [PubMed - indexed for MEDLINE]Related articles

Insulin autoantibody isotypes during the prediabetic process in young children with increased genetic risk of type 1 diabetes.

Hoppu S, Ronkainen MS, Kimpimäki T, Simell S, Korhonen S, Ilonen J, Simell O, Knip M.

Pediatr Res. 2004 Feb;55(2):236-42. Epub 2003 Nov 6.PMID: 14605243 [PubMed - indexed for MEDLINE]Related articles

Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren.

Kulmala P, Rahko J, Savola K, Vähäsalo P, Veijola R, Sjöroos M, Reunanen A, Ilonen J, Knip M.

Diabetologia. 2000 Apr;43(4):457-64.PMID: 10819239 [PubMed - indexed for MEDLINE]Related articles

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

Walter M, Albert E, Conrad M, Keller E, Hummel M, Ferber K, Barratt BJ, Todd JA, Ziegler AG, Bonifacio E.

Diabetologia. 2003 May;46(5):712-20. Epub 2003 May 16.PMID: 12750767 [PubMed - indexed for MEDLINE]Related articles

CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry.

Van der Auwera BJ, Vandewalle CL, Schuit FC, Winnock F, De Leeuw IH, Van Imschoot S, Lamberigts G, Gorus FK.

Clin Exp Immunol. 1997 Oct;110(1):98-103.PMID: 9353155 [PubMed - indexed for MEDLINE]Related articlesFree article

The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.

Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C, Cossu E, Pozzilli P, Falorni A, Buzzetti R; NIRAD Study Group.

Diabetes Care. 2008 Mar;31(3):534-8. Epub 2007 Dec 4.PMID: 18056891 [PubMed - indexed for MEDLINE]Related articlesFree article

The HLA-DRB, -DQB polymorphism and anti-insulin antibody response in Slovenian patients with type 1 diabetes.

Battelino T, Ursic-Bratina N, Dolzan V, Stopar-Obreza M, Pozzilli P, Krzisnik C, Vidan-Jeras B.

Eur J Immunogenet. 2003 Jun;30(3):223-7.PMID: 12787001 [PubMed - indexed for MEDLINE]Related articles

Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.

Redondo MJ, Babu S, Zeidler A, Orban T, Yu L, Greenbaum C, Palmer JP, Cuthbertson D, Eisenbarth GS, Krischer JP, Schatz D; Diabetes Prevention Trial Type 1 Study Group.

J Clin Endocrinol Metab. 2006 May;91(5):1705-13. Epub 2006 Feb 7.PMID: 16464953 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?

Tiberti C, Buzzetti R, Anastasi E, Dotta F, Vasta M, Petrone A, Cervoni M, Torresi P, Vecci E, Multari G, Di Mario U.

Diabetes Metab Res Rev. 2000 Jan-Feb;16(1):8-14.PMID: 10707033 [PubMed - indexed for MEDLINE]Related articles

Cytotoxic T lymphocyte antigen 4 gene polymorphism confers susceptibility to type 1 diabetes in Japanese children: analysis of association with HLA genotypes and autoantibodies.

Kikuoka N, Sugihara S, Yanagawa T, Ikezaki A, Kim HS, Matsuoka H, Kobayashi Y, Wataki K, Konda S, Sato H, Miyamoto S, Sasaki N, Sakamaki T, Niimi H, Murata M.

Clin Endocrinol (Oxf). 2001 Nov;55(5):597-603.PMID: 11894970 [PubMed - indexed for MEDLINE]Related articles

Identification of prediabetes in first-degree relatives at intermediate risk of type I diabetes.

Truyen I, De Grijse J, Weets I, Kaufman L, Pipeleers L, Nanos N, Decochez K, Hilbrands R, Kaufman JM, Keymeulen B, Mathieu C, Van Gaal L, Pipeleers DG, Gorus FK; Belgian Diabetes Registry.

Clin Exp Immunol. 2007 Aug;149(2):243-50. Epub 2007 May 22.PMID: 17521324 [PubMed - indexed for MEDLINE]Related articlesFree article

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.

Näntö-Salonen K, Kupila A, Simell S, Siljander H, Salonsaari T, Hekkala A, Korhonen S, Erkkola R, Sipilä JI, Haavisto L, Siltala M, Tuominen J, Hakalax J, Hyöty H, Ilonen J, Veijola R, Simell T, Knip M, Simell O.

Lancet. 2008 Nov 15;372(9651):1746-55. Epub 2008 Sep 22.PMID: 18814906 [PubMed - indexed for MEDLINE]Related articles