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    Results: 1 to 20 of 101

    1.

    Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

    DeAngelis AM, Heinrich G, Dai T, Bowman TA, Patel PR, Lee SJ, Hong EG, Jung DY, Assmann A, Kulkarni RN, Kim JK, Najjar SM.

    Diabetes. 2008 Sep;57(9):2296-303. Epub 2008 Jun 10.PMID: 18544705 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.

    Park SY, Cho YR, Kim HJ, Hong EG, Higashimori T, Lee SJ, Goldberg IJ, Shulman GI, Najjar SM, Kim JK.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E517-24. Epub 2006 Apr 25.PMID: 16638824 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.

    Xu E, Dubois MJ, Leung N, Charbonneau A, Turbide C, Avramoglu RK, DeMarte L, Elchebly M, Streichert T, Lévy E, Beauchemin N, Marette A.

    Endocrinology. 2009 Aug;150(8):3503-12. Epub 2009 Apr 30.PMID: 19406938 [PubMed - indexed for MEDLINE]Related articles

    4.

    Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice.

    Lee SJ, Heinrich G, Fedorova L, Al-Share QY, Ledford KJ, Fernstrom MA, McInerney MF, Erickson SK, Gatto-Weis C, Najjar SM.

    Gastroenterology. 2008 Dec;135(6):2084-95. Epub 2008 Aug 20.PMID: 18848945 [PubMed - indexed for MEDLINE]Related articles

    5.

    Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.

    Dai T, Abou-Rjaily GA, Al-Share' QY, Yang Y, Fernström MA, Deangelis AM, Lee AD, Sweetman L, Amato A, Pasquali M, Lopaschuk GD, Erickson SK, Najjar SM.

    J Biol Chem. 2004 Oct 22;279(43):45155-61. Epub 2004 Aug 16.PMID: 15316023 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    CEACAM1 regulates insulin clearance in liver.

    Poy MN, Yang Y, Rezaei K, Fernström MA, Lee AD, Kido Y, Erickson SK, Najjar SM.

    Nat Genet. 2002 Mar;30(3):270-6. Epub 2002 Feb 19.PMID: 11850617 [PubMed - indexed for MEDLINE]Related articles

    7.

    Insulin acutely decreases hepatic fatty acid synthase activity.

    Najjar SM, Yang Y, Fernström MA, Lee SJ, Deangelis AM, Rjaily GA, Al-Share QY, Dai T, Miller TA, Ratnam S, Ruch RJ, Smith S, Lin SH, Beauchemin N, Oyarce AM.

    Cell Metab. 2005 Jul;2(1):43-53.PMID: 16054098 [PubMed - indexed for MEDLINE]Related articles

    8.

    Regulation of insulin action by CEACAM1.

    Najjar SM.

    Trends Endocrinol Metab. 2002 Aug;13(6):240-5. Review.PMID: 12128284 [PubMed - indexed for MEDLINE]Related articles

    9.

    Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

    Tang J, Neidigh JL, Cooksey RC, McClain DA.

    Diabetes. 2000 Sep;49(9):1492-9.PMID: 10969833 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Deletion of cd39/entpd1 results in hepatic insulin resistance.

    Enjyoji K, Kotani K, Thukral C, Blumel B, Sun X, Wu Y, Imai M, Friedman D, Csizmadia E, Bleibel W, Kahn BB, Robson SC.

    Diabetes. 2008 Sep;57(9):2311-20. Epub 2008 Jun 20.PMID: 18567823 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

    Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB.

    J Clin Invest. 2004 Dec;114(11):1666-75.PMID: 15578099 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Glucose metabolism in vivo in four commonly used inbred mouse strains.

    Berglund ED, Li CY, Poffenberger G, Ayala JE, Fueger PT, Willis SE, Jewell MM, Powers AC, Wasserman DH.

    Diabetes. 2008 Jul;57(7):1790-9. Epub 2008 Apr 8.PMID: 18398139 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.

    Mulder H, Sörhede-Winzell M, Contreras JA, Fex M, Ström K, Ploug T, Galbo H, Arner P, Lundberg C, Sundler F, Ahrén B, Holm C.

    J Biol Chem. 2003 Sep 19;278(38):36380-8. Epub 2003 Jun 30.PMID: 12835327 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance.

    Fex M, Wierup N, Nitert MD, Ristow M, Mulder H.

    J Endocrinol. 2007 Sep;194(3):551-5. Erratum in: J Endocrinol. 2007 Dec;195(3):537. PMID: 17761894 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.
    16.

    CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation.

    Abou-Rjaily GA, Lee SJ, May D, Al-Share QY, Deangelis AM, Ruch RJ, Neumaier M, Kalthoff H, Lin SH, Najjar SM.

    J Clin Invest. 2004 Oct;114(7):944-52.PMID: 15467833 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

    Wilkes JJ, Lloyd DJ, Gekakis N.

    Diabetes. 2009 May;58(5):1133-43. Epub 2009 Feb 10.PMID: 19208906 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

    Walz HA, Härndahl L, Wierup N, Zmuda-Trzebiatowska E, Svennelid F, Manganiello VC, Ploug T, Sundler F, Degerman E, Ahrén B, Holst LS.

    J Endocrinol. 2006 Jun;189(3):629-41.PMID: 16731793 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes.

    Kotronen A, Juurinen L, Tiikkainen M, Vehkavaara S, Yki-Järvinen H.

    Gastroenterology. 2008 Jul;135(1):122-30. Epub 2008 Mar 21.PMID: 18474251 [PubMed - indexed for MEDLINE]Related articles

    20.

    Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.

    Nagasumi K, Esaki R, Iwachidow K, Yasuhara Y, Ogi K, Tanaka H, Nakata M, Yano T, Shimakawa K, Taketomi S, Takeuchi K, Odaka H, Kaisho Y.

    Diabetes. 2009 May;58(5):1067-76. Erratum in: Diabetes. 2009 Jul;58(7):1721. PMID: 19401434 [PubMed - indexed for MEDLINE]Related articlesFree article