PubMed

Progesterone in traumatic brain injury: time to move on to phase III trials.

Vandromme M, Melton SM, Kerby JD.

Crit Care. 2008;12(3):153. Epub 2008 May 29.PMID: 18522765 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial.

Xiao G, Wei J, Yan W, Wang W, Lu Z.

Crit Care. 2008;12(2):R61. Epub 2008 Apr 30.PMID: 18447940 [PubMed - indexed for MEDLINE]Related articlesFree article

ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury.

Wright DW, Kellermann AL, Hertzberg VS, Clark PL, Frankel M, Goldstein FC, Salomone JP, Dent LL, Harris OA, Ander DS, Lowery DW, Patel MM, Denson DD, Gordon AB, Wald MM, Gupta S, Hoffman SW, Stein DG.

Ann Emerg Med. 2007 Apr;49(4):391-402, 402.e1-2. Epub 2006 Sep 29.PMID: 17011666 [PubMed - indexed for MEDLINE]Related articles

Clinical trials in traumatic brain injury: current problems and future solutions.

Maas AI, Marmarou A, Murray GD, Steyerberg EW.

Acta Neurochir Suppl. 2004;89:113-8.PMID: 15335110 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial.

Maas AI, Murray G, Henney H 3rd, Kassem N, Legrand V, Mangelus M, Muizelaar JP, Stocchetti N, Knoller N; Pharmos TBI investigators.

Lancet Neurol. 2006 Jan;5(1):38-45.PMID: 16361021 [PubMed - indexed for MEDLINE]Related articles

Lessons from epidemiologic studies in clinical trials of traumatic brain injury.

Farin A, Marshall LF.

Acta Neurochir Suppl. 2004;89:101-7.PMID: 15335108 [PubMed - indexed for MEDLINE]Related articles

Progesterone as a neuroprotective factor in traumatic and ischemic brain injury.

Sayeed I, Stein DG.

Prog Brain Res. 2009;175:219-37. Review.PMID: 19660659 [PubMed - indexed for MEDLINE]Related articles

Regional differences in patient characteristics, case management, and outcomes in traumatic brain injury: experience from the tirilazad trials.

Hukkelhoven CW, Steyerberg EW, Farace E, Habbema JD, Marshall LF, Maas AI.

J Neurosurg. 2002 Sep;97(3):549-57.PMID: 12296638 [PubMed - indexed for MEDLINE]Related articles

Progesterone for the treatment of experimental brain injury; a systematic review.

Gibson CL, Gray LJ, Bath PM, Murphy SP.

Brain. 2008 Feb;131(Pt 2):318-28. Epub 2007 Aug 21. Review.PMID: 17715141 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent advances in the development of multifactorial therapies for the treatment of traumatic brain injury.

Vink R, Van Den Heuvel C.

Expert Opin Investig Drugs. 2004 Oct;13(10):1263-74. Review.PMID: 15461556 [PubMed - indexed for MEDLINE]Related articles

Emerging treatments for traumatic brain injury.

Xiong Y, Mahmood A, Chopp M.

Expert Opin Emerg Drugs. 2009 Mar;14(1):67-84. Review.PMID: 19249984 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain trauma.

Servadei F, Bricolo A, Lagarrigue J, Lobato R, Persson L.

J Neurosurg. 2003 Jun;98(6):1326-8; author reply 1328-9. No abstract available. PMID: 12816286 [PubMed - indexed for MEDLINE]Related articles

Neuroprotective agents in traumatic brain injury.

Maas AI.

Expert Opin Investig Drugs. 2001 Apr;10(4):753-67. Review.PMID: 11281824 [PubMed - indexed for MEDLINE]Related articles

Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies.

Bullock MR, Lyeth BG, Muizelaar JP.

Neurosurgery. 1999 Aug;45(2):207-17; discussion 217-20. Review.PMID: 10449064 [PubMed - indexed for MEDLINE]Related articles

The effect of the selective NMDA receptor antagonist traxoprodil in the treatment of traumatic brain injury.

Yurkewicz L, Weaver J, Bullock MR, Marshall LF.

J Neurotrauma. 2005 Dec;22(12):1428-43.PMID: 16379581 [PubMed - indexed for MEDLINE]Related articles

Dosing and safety of cyclosporine in patients with severe brain injury.

Hatton J, Rosbolt B, Empey P, Kryscio R, Young B.

J Neurosurg. 2008 Oct;109(4):699-707.PMID: 18826358 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of methylphenidate in traumatic brain injury.

Siddall OM.

Ann Pharmacother. 2005 Jul-Aug;39(7-8):1309-13. Epub 2005 May 24. Review.PMID: 15914519 [PubMed - indexed for MEDLINE]Related articles

'No Time to be Lost!' Ethical considerations on consent for inclusion in emergency pharmacological research in severe traumatic brain injury in the European Union.

Kompanje EJ.

Sci Eng Ethics. 2007 Sep;13(3):371-81.PMID: 18210230 [PubMed - indexed for MEDLINE]Related articlesFree article

Can we improve neurological outcomes in severe traumatic brain injury? Something old (early prophylactic hypothermia) and something new (erythropoietin).

Nichol AD, Cooper DJ; POLAR Study Investigators on behalf of the ANZICS-Clinical Trials Group; EPO Study Investigators on behalf of the ANZICS-Clinical Trials Group.

Injury. 2009 May;40(5):471-8. Epub 2009 Apr 15. Review.PMID: 19371869 [PubMed - indexed for MEDLINE]Related articles

Neurological deterioration as a potential alternative endpoint in human clinical trials of experimental pharmacological agents for treatment of severe traumatic brain injuries. Executive Committee of the International Selfotel Trial.

Morris GF, Juul N, Marshall SB, Benedict B, Marshall LF.

Neurosurgery. 1998 Dec;43(6):1369-72; discussion 1372-4.PMID: 9848851 [PubMed - indexed for MEDLINE]Related articles