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    Results: 1 to 20 of 126

    1.

    Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.

    Edfalk S, Steneberg P, Edlund H.

    Diabetes. 2008 Sep;57(9):2280-7. Epub 2008 Jun 2.PMID: 18519800 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release.

    Chu ZL, Carroll C, Alfonso J, Gutierrez V, He H, Lucman A, Pedraza M, Mondala H, Gao H, Bagnol D, Chen R, Jones RM, Behan DP, Leonard J.

    Endocrinology. 2008 May;149(5):2038-47. Epub 2008 Jan 17.PMID: 18202141 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones.

    Kokrashvili Z, Mosinger B, Margolskee RF.

    Am J Clin Nutr. 2009 Sep;90(3):822S-825S. Epub 2009 Jul 1.PMID: 19571229 [PubMed - indexed for MEDLINE]Related articles

    4.

    The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

    Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, Poitout V.

    Diabetes. 2008 Sep;57(9):2432-7. Epub 2008 Jun 16. Erratum in: Diabetes. 2008 Nov;57(11):3166. PMID: 18559658 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.

    Schnell S, Schaefer M, Schöfl C.

    Mol Cell Endocrinol. 2007 Jan 15;263(1-2):173-80. Epub 2006 Nov 13.PMID: 17101212 [PubMed - indexed for MEDLINE]Related articles

    6.

    Pax6 and Pdx1 are required for production of glucose-dependent insulinotropic polypeptide in proglucagon-expressing L cells.

    Fujita Y, Chui JW, King DS, Zhang T, Seufert J, Pownall S, Cheung AT, Kieffer TJ.

    Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E648-57. Epub 2008 Jul 1.PMID: 18593849 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.

    Nagasumi K, Esaki R, Iwachidow K, Yasuhara Y, Ogi K, Tanaka H, Nakata M, Yano T, Shimakawa K, Taketomi S, Takeuchi K, Odaka H, Kaisho Y.

    Diabetes. 2009 May;58(5):1067-76. Erratum in: Diabetes. 2009 Jul;58(7):1721. PMID: 19401434 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.

    Theodorakis MJ, Carlson O, Michopoulos S, Doyle ME, Juhaszova M, Petraki K, Egan JM.

    Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E550-9. Epub 2005 Oct 11.PMID: 16219666 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

    Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

    Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.

    Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G.

    Nat Med. 2005 Jan;11(1):90-4. Epub 2004 Dec 26.PMID: 15619630 [PubMed - indexed for MEDLINE]Related articles

    11.

    Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.

    Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C, Fornwald JA, Ignar DM, Jenkinson S.

    Br J Pharmacol. 2006 Jul;148(5):619-28. Epub 2006 May 15.PMID: 16702987 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Stimulation of incretin secretion by dietary lipid: is it dose dependent?

    Yoder SM, Yang Q, Kindel TL, Tso P.

    Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G299-305. Epub 2009 Jun 11.PMID: 19520739 [PubMed - indexed for MEDLINE]Related articles

    13.

    Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

    Salehi A, Flodgren E, Nilsson NE, Jimenez-Feltstrom J, Miyazaki J, Owman C, Olde B.

    Cell Tissue Res. 2005 Nov;322(2):207-15. Epub 2005 Nov 3.PMID: 16044321 [PubMed - indexed for MEDLINE]Related articles

    14.

    The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.

    Boucher MJ, Simoneau M, Edlund H.

    Endocrinology. 2009 Jan;150(1):87-97. Epub 2008 Sep 4.PMID: 18772243 [PubMed - indexed for MEDLINE]Related articles

    15.

    The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse.

    Steneberg P, Rubins N, Bartoov-Shifman R, Walker MD, Edlund H.

    Cell Metab. 2005 Apr;1(4):245-58.PMID: 16054069 [PubMed - indexed for MEDLINE]Related articles

    16.

    Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance.

    Muscelli E, Mari A, Natali A, Astiarraga BD, Camastra S, Frascerra S, Holst JJ, Ferrannini E.

    Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1144-50. Epub 2006 Feb 14.PMID: 16478775 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion.

    Tomita T, Masuzaki H, Iwakura H, Fujikura J, Noguchi M, Tanaka T, Ebihara K, Kawamura J, Komoto I, Kawaguchi Y, Fujimoto K, Doi R, Shimada Y, Hosoda K, Imamura M, Nakao K.

    Diabetologia. 2006 May;49(5):962-8. Epub 2006 Mar 9.PMID: 16525841 [PubMed - indexed for MEDLINE]Related articles

    18.

    Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance.

    Vollmer K, Holst JJ, Baller B, Ellrichmann M, Nauck MA, Schmidt WE, Meier JJ.

    Diabetes. 2008 Mar;57(3):678-87. Epub 2007 Dec 5.PMID: 18057091 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice.

    Tan CP, Feng Y, Zhou YP, Eiermann GJ, Petrov A, Zhou C, Lin S, Salituro G, Meinke P, Mosley R, Akiyama TE, Einstein M, Kumar S, Berger JP, Mills SG, Thornberry NA, Yang L, Howard AD.

    Diabetes. 2008 Aug;57(8):2211-9. Epub 2008 May 13.PMID: 18477808 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Nutrient-driven incretin secretion into intestinal lymph is different between diabetic Goto-Kakizaki rats and Wistar rats.

    Kindel TL, Yang Q, Yoder SM, Tso P.

    Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G168-74. Epub 2008 Dec 4.PMID: 19056762 [PubMed - indexed for MEDLINE]Related articles

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