PubMed

Pyruvate dehydrogenase kinase 4: regulation by thiazolidinediones and implication in glyceroneogenesis in adipose tissue.

Cadoudal T, Distel E, Durant S, Fouque F, Blouin JM, Collinet M, Bortoli S, Forest C, Benelli C.

Diabetes. 2008 Sep;57(9):2272-9. Epub 2008 Jun 2.PMID: 18519799 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.

Cadoudal T, Blouin JM, Collinet M, Fouque F, Tan GD, Loizon E, Beale EG, Frayn KN, Karpe F, Vidal H, Benelli C, Forest C.

Diabetologia. 2007 Mar;50(3):666-75. Epub 2007 Jan 23.PMID: 17242918 [PubMed - indexed for MEDLINE]Related articles

Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes.

Cadoudal T, Glorian M, Massias A, Fouque F, Forest C, Benelli C.

J Nutr. 2008 Jun;138(6):1004-9.PMID: 18492826 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation.

Leroyer SN, Tordjman J, Chauvet G, Quette J, Chapron C, Forest C, Antoine B.

J Biol Chem. 2006 May 12;281(19):13141-9. Epub 2006 Mar 8.PMID: 16524879 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone.

Holness MJ, Bulmer K, Smith ND, Sugden MC.

Biochem J. 2003 Feb 1;369(Pt 3):687-95.PMID: 12435272 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute and selective inhibition of adipocyte glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase by interferon gamma.

Khazen W, Distel E, Collinet M, Chaves VE, M'Bika JP, Chany C, Achour A, Benelli C, Forest C.

Endocrinology. 2007 Aug;148(8):4007-14. Epub 2007 May 10.PMID: 17495004 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-alpha: implications for glucose-stimulated insulin secretion.

Sugden MC, Bulmer K, Augustine D, Holness MJ.

Diabetes. 2001 Dec;50(12):2729-36.PMID: 11723055 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells.

Tordjman J, Chauvet G, Quette J, Beale EG, Forest C, Antoine B.

J Biol Chem. 2003 May 23;278(21):18785-90. Epub 2003 Mar 18.PMID: 12644461 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.

Matsuda J, Hosoda K, Itoh H, Son C, Doi K, Hanaoka I, Inoue G, Nishimura H, Yoshimasa Y, Yamori Y, Odaka H, Nakao K.

Diabetes. 1998 Nov;47(11):1809-14.PMID: 9792555 [PubMed - indexed for MEDLINE]Related articlesFree article

Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.

Abbot EL, McCormack JG, Reynet C, Hassall DG, Buchan KW, Yeaman SJ.

FEBS J. 2005 Jun;272(12):3004-14.PMID: 15955060 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct effects of leptin on brown and white adipose tissue.

Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, Boss O, Pernin A, Chin WW, Cusin I, Rohner-Jeanrenaud F, Burger AG, Zapf J, Meier CA.

J Clin Invest. 1997 Dec 1;100(11):2858-64.PMID: 9389752 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding.

Holness MJ, Kraus A, Harris RA, Sugden MC.

Diabetes. 2000 May;49(5):775-81.PMID: 10905486 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression.

Zhang Y, Ma K, Sadana P, Chowdhury F, Gaillard S, Wang F, McDonnell DP, Unterman TG, Elam MB, Park EA.

J Biol Chem. 2006 Dec 29;281(52):39897-906. Epub 2006 Nov 1.PMID: 17079227 [PubMed - indexed for MEDLINE]Related articlesFree article

Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues.

Wu P, Blair PV, Sato J, Jaskiewicz J, Popov KM, Harris RA.

Arch Biochem Biophys. 2000 Sep 1;381(1):1-7.PMID: 11019813 [PubMed - indexed for MEDLINE]Related articles

Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 protein expression in starvation and after refeeding.

Sugden MC, Bulmer K, Gibbons GF, Holness MJ.

Arch Biochem Biophys. 2001 Nov 15;395(2):246-52.PMID: 11697863 [PubMed - indexed for MEDLINE]Related articles

Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-alpha ligands, glucocorticoids, and insulin.

Huang B, Wu P, Bowker-Kinley MM, Harris RA.

Diabetes. 2002 Feb;51(2):276-83.PMID: 11812733 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione.

Tordjman J, Leroyer S, Chauvet G, Quette J, Chauvet C, Tomkiewicz C, Chapron C, Barouki R, Forest C, Aggerbeck M, Antoine B.

J Biol Chem. 2007 Aug 10;282(32):23591-602. Epub 2007 Jun 1.PMID: 17545671 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic potential of the mammalian pyruvate dehydrogenase kinases in the prevention of hyperglycaemia.

Sugden MC, Holness MJ.

Curr Drug Targets Immune Endocr Metabol Disord. 2002 Jul;2(2):151-65. Review.PMID: 12476789 [PubMed - indexed for MEDLINE]Related articles

Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats.

Kramer D, Shapiro R, Adler A, Bush E, Rondinone CM.

Metabolism. 2001 Nov;50(11):1294-300.PMID: 11699047 [PubMed - indexed for MEDLINE]Related articles

Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression.

Sugden MC, Kraus A, Harris RA, Holness MJ.

Biochem J. 2000 Mar 15;346 Pt 3:651-7.PMID: 10698691 [PubMed - indexed for MEDLINE]Related articlesFree article