Warning: The NCBI web site requires JavaScript to function. more...
Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142.
Olivieri KC, Scoggins RM, Broderick B, Powell ML, Alexander MA, Hammarskjöld ML, Rekosh D, Camerini D.
Retrovirology. 2008 May 29;5:42.
Related citations
Nef alleles from human immunodeficiency virus type 1-infected long-term-nonprogressor hemophiliacs with or without late disease progression are defective in enhancing virus replication and CD4 down-regulation.
Crotti A, Neri F, Corti D, Ghezzi S, Heltai S, Baur A, Poli G, Santagostino E, Vicenzi E.
J Virol. 2006 Nov;80(21):10663-74. Epub 2006 Aug 30.
Pathogenesis of primary R5 human immunodeficiency virus type 1 clones in SCID-hu mice.
Scoggins RM, Taylor JR Jr, Patrie J, van't Wout AB, Schuitemaker H, Camerini D.
J Virol. 2000 Apr;74(7):3205-16.
Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication.
Argañaraz ER, Schindler M, Kirchhoff F, Cortes MJ, Lama J.
J Biol Chem. 2003 Sep 5;278(36):33912-9. Epub 2003 Jun 19.
The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1.
Olivieri K, Scoggins RM, Bor YC, Matthews A, Mark D, Taylor JR Jr, Chernauskas D, Hammarskjöld ML, Rekosh D, Camerini D.
Virology. 2007 Feb 5;358(1):23-38. Epub 2006 Sep 26.
CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates.
Gray LR, Gabuzda D, Cowley D, Ellett A, Chiavaroli L, Wesselingh SL, Churchill MJ, Gorry PR.
J Neurovirol. 2011 Feb;17(1):82-91. Epub 2010 Nov 30.
Inefficient enhancement of viral infectivity and CD4 downregulation by human immunodeficiency virus type 1 Nef from Japanese long-term nonprogressors.
Tobiume M, Takahoko M, Yamada T, Tatsumi M, Iwamoto A, Matsuda M.
J Virol. 2002 Jun;76(12):5959-65.
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection.
Wildum S, Schindler M, Münch J, Kirchhoff F.
J Virol. 2006 Aug;80(16):8047-59.
CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 nef protein in pediatric AIDS progression.
Casartelli N, Di Matteo G, Potestà M, Rossi P, Doria M.
J Virol. 2003 Nov;77(21):11536-45.
Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue.
Schindler M, Rajan D, Specht A, Ritter C, Pulkkinen K, Saksela K, Kirchhoff F.
J Virol. 2007 Dec;81(23):13005-14. Epub 2007 Sep 19.
HIV Nef: role in pathogenesis and viral fitness.
Ariën KK, Verhasselt B.
Curr HIV Res. 2008 May;6(3):200-8. Review.
R5 human immunodeficiency virus type 1 infection of fetal thymic organ culture induces cytokine and CCR5 expression.
Choudhary SK, Choudhary NR, Kimbrell KC, Colasanti J, Ziogas A, Kwa D, Schuitemaker H, Camerini D.
J Virol. 2005 Jan;79(1):458-71.
CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable.
Agopian K, Wei BL, Garcia JV, Gabuzda D.
Virology. 2007 Feb 5;358(1):119-35. Epub 2006 Sep 18.
Requirement of nef for HIV-1 infectivity is biased by the expression levels of Env in the virus-producing cells and CD4 in the target cells.
Tobiume M, Tokunaga K, Kiyokawa E, Takahoko M, Mochizuki N, Tatsumi M, Matsuda M.
Arch Virol. 2001;146(9):1739-51.
Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS.
Carl S, Greenough TC, Krumbiegel M, Greenberg M, Skowronski J, Sullivan JL, Kirchhoff F.
J Virol. 2001 Apr;75(8):3657-65.
Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source.
Gray L, Churchill MJ, Sterjovski J, Witlox K, Learmont JC, Sullivan JS, Wesselingh SL, Gabuzda D, Cunningham AL, McPhee DA, Gorry PR.
Virol J. 2007 Jul 16;4:75.
Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1.
Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC.
J Virol. 2007 May;81(9):4776-86. Epub 2007 Feb 28.
HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-tagged HIV-1 reporter virus.
Brown A, Gartner S, Kawano T, Benoit N, Cheng-Mayer C.
J Leukoc Biol. 2005 Sep;78(3):675-85. Epub 2005 Jul 6.
Conservation of the central proline-rich (PxxP) motifs of human immunodeficiency virus type 1 Nef protein during the disease progression in two hemophiliac patients.
Asamitsu K, Morishima T, Tsuchie H, Kurimura T, Okamoto T.
FEBS Lett. 1999 Oct 15;459(3):399-404.
Deletion of N-terminal myristoylation site of HIV Nef abrogates both MHC-1 and CD4 down-regulation.
Peng B, Robert-Guroff M.
Immunol Lett. 2001 Oct 1;78(3):195-200.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on