PubMed

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21.PMID: 18507839 [PubMed - indexed for MEDLINE]Related articlesFree article

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.

Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM.

J Neuroinflammation. 2007 Sep 19;4:23.PMID: 17880684 [PubMed - indexed for MEDLINE]Related articlesFree article

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS.

FASEB J. 2005 Mar;19(3):395-7. Epub 2004 Dec 13.PMID: 15596482 [PubMed - indexed for MEDLINE]Related articlesFree article

Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS.

J Pharmacol Exp Ther. 2003 Apr;305(1):212-8.PMID: 12649371 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase.

Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM.

J Pharmacol Exp Ther. 2006 Oct;319(1):44-52. Epub 2006 Jun 28.PMID: 16807359 [PubMed - indexed for MEDLINE]Related articlesFree article

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS.

J Biol Chem. 2004 Jan 9;279(2):1415-21. Epub 2003 Oct 24.PMID: 14578353 [PubMed - indexed for MEDLINE]Related articlesFree article

Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.

Qian L, Wei SJ, Zhang D, Hu X, Xu Z, Wilson B, El-Benna J, Hong JS, Flood PM.

J Immunol. 2008 Jul 1;181(1):660-8.PMID: 18566433 [PubMed - indexed for MEDLINE]Related articlesFree article

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.

Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS.

FASEB J. 2005 Apr;19(6):489-96.PMID: 15790998 [PubMed - indexed for MEDLINE]Related articlesFree article

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14.PMID: 18474101 [PubMed - indexed for MEDLINE]Related articlesFree article

Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

Li Y, Hu X, Liu Y, Bao Y, An L.

Neuropharmacology. 2009 Mar;56(3):580-9. Epub 2008 Nov 21.PMID: 19049811 [PubMed - indexed for MEDLINE]Related articles

Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.

Yang S, Yang J, Yang Z, Chen P, Fraser A, Zhang W, Pang H, Gao X, Wilson B, Hong JS, Block ML.

J Pharmacol Exp Ther. 2006 Nov;319(2):595-603. Epub 2006 Aug 4.PMID: 16891616 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation.

Moon M, Kim HG, Hwang L, Seo JH, Kim S, Hwang S, Kim S, Lee D, Chung H, Oh MS, Lee KT, Park S.

Neurotox Res. 2009 May;15(4):332-47. Epub 2009 Mar 17.PMID: 19384567 [PubMed - indexed for MEDLINE]Related articles

Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.

Gao HM, Liu B, Hong JS.

J Neurosci. 2003 Jul 16;23(15):6181-7.PMID: 12867501 [PubMed - indexed for MEDLINE]Related articlesFree article

Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection.

Qin L, Liu Y, Qian X, Hong JS, Block ML.

Ann N Y Acad Sci. 2005 Aug;1053:107-20.PMID: 16179514 [PubMed - indexed for MEDLINE]Related articles

Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM.

J Immunol. 2007 Jul 15;179(2):1198-209.PMID: 17617613 [PubMed - indexed for MEDLINE]Related articlesFree article

Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.

Tian YY, An LJ, Jiang L, Duan YL, Chen J, Jiang B.

Life Sci. 2006 Dec 23;80(3):193-9. Epub 2006 Sep 20.PMID: 17049947 [PubMed - indexed for MEDLINE]Related articles

Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration?

Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS.

Environ Health Perspect. 2008 May;116(5):593-8.PMID: 18470306 [PubMed - indexed for MEDLINE]Related articlesFree article

Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia.

Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, Yang S, Hong JS.

Brain Res Mol Brain Res. 2005 Mar 24;134(1):162-9. Epub 2004 Nov 25.PMID: 15790540 [PubMed - indexed for MEDLINE]Related articles

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

Qin L, Liu Y, Cooper C, Liu B, Wilson B, Hong JS.

J Neurochem. 2002 Nov;83(4):973-83.PMID: 12421370 [PubMed - indexed for MEDLINE]Related articles

Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.

Zhang W, Wang T, Qin L, Gao HM, Wilson B, Ali SF, Zhang W, Hong JS, Liu B.

FASEB J. 2004 Mar;18(3):589-91. Epub 2004 Jan 20.PMID: 14734632 [PubMed - indexed for MEDLINE]Related articlesFree article