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VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult.

Ryu JK, McLarnon JG.

J Neuroinflammation. 2008 May 20;5:18.PMID: 18492281 [PubMed - indexed for MEDLINE]Related articlesFree article

Thalidomide inhibition of vascular remodeling and inflammatory reactivity in the quinolinic acid-injected rat striatum.

Ryu JK, Jantaratnotai N, McLarnon JG.

Neuroscience. 2009 Oct 6;163(2):601-8. Epub 2009 Jul 7.PMID: 19591904 [PubMed - indexed for MEDLINE]Related articles

Depletion of neutrophils reduces neuronal degeneration and inflammatory responses induced by quinolinic acid in vivo.

Ryu JK, Tran KC, McLarnon JG.

Glia. 2007 Mar;55(4):439-51.PMID: 17203474 [PubMed - indexed for MEDLINE]Related articles

Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum.

Ryu JK, Choi HB, McLarnon JG.

Neurobiol Dis. 2005 Nov;20(2):550-61.PMID: 15916899 [PubMed - indexed for MEDLINE]Related articles

Design, synthesis, and evaluation of original carriers for targeting vascular endothelial growth factor receptor interactions.

Gonçalves M, Estieu-Gionnet K, Berthelot T, Laïn G, Bayle M, Canron X, Betz N, Bikfalvi A, Déléris G.

Pharm Res. 2005 Aug;22(8):1411-21. Epub 2005 Aug 3.PMID: 16078152 [PubMed - indexed for MEDLINE]Related articles

Protective role of melatonin in domoic acid-induced neuronal damage in the hippocampus of adult rats.

Ananth C, Gopalakrishnakone P, Kaur C.

Hippocampus. 2003;13(3):375-87.PMID: 12722978 [PubMed - indexed for MEDLINE]Related articles

Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease.

Ryu JK, Choi HB, McLarnon JG.

Neuroscience. 2006 Sep 15;141(4):1835-48. Epub 2006 Jun 30.PMID: 16809003 [PubMed - indexed for MEDLINE]Related articles

Inhibition of integrin alphavbeta3 ameliorates focal cerebral ischemic damage in the rat middle cerebral artery occlusion model.

Shimamura N, Matchett G, Yatsushige H, Calvert JW, Ohkuma H, Zhang J.

Stroke. 2006 Jul;37(7):1902-9. Epub 2006 Jun 1.PMID: 16741177 [PubMed - indexed for MEDLINE]Related articlesFree article

Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed AD brain.

Ryu JK, Cho T, Wang YT, McLarnon JG.

J Neuroinflammation. 2009 Dec 23;6:39.PMID: 20030829 [PubMed - indexed for MEDLINE]Related articlesFree article

The 1993 Upjohn Award Lecture. Quinolinic acid induced brain neurotransmitter deficits: modulation by endogenous excitotoxin antagonists.

Jhamandas KH, Boegman RJ, Beninger RJ.

Can J Physiol Pharmacol. 1994 Dec;72(12):1473-82. Review.PMID: 7736338 [PubMed - indexed for MEDLINE]Related articles

Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neurochemical deficits in a rodent model of Huntington's disease.

Araujo DM, Hilt DC.

Neuroscience. 1997 Dec;81(4):1099-110.PMID: 9330371 [PubMed - indexed for MEDLINE]Related articles

Relative resistance of striatal neurons containing calbindin or parvalbumin to quinolinic acid-mediated excitotoxicity compared to other striatal neuron types.

Figueredo-Cardenas G, Harris CL, Anderson KD, Reiner A.

Exp Neurol. 1998 Feb;149(2):356-72.PMID: 9500958 [PubMed - indexed for MEDLINE]Related articles

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain.

Ryu JK, McLarnon JG.

J Cell Mol Med. 2009 Sep;13(9A):2911-25. Epub 2008 Jul 24.PMID: 18657226 [PubMed - in process]Related articles

Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease.

Senatorov VV, Ren M, Kanai H, Wei H, Chuang DM.

Mol Psychiatry. 2004 Apr;9(4):371-85.PMID: 14702090 [PubMed - indexed for MEDLINE]Related articles

Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum.

Popoli P, Pintor A, Domenici MR, Frank C, Tebano MT, Pèzzola A, Scarchilli L, Quarta D, Reggio R, Malchiodi-Albedi F, Falchi M, Massotti M.

J Neurosci. 2002 Mar 1;22(5):1967-75.PMID: 11880527 [PubMed - indexed for MEDLINE]Related articlesFree article

Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease.

Ryu JK, McLarnon JG.

Neuroreport. 2008 Nov 19;19(17):1715-9.PMID: 18852683 [PubMed - indexed for MEDLINE]Related articles

Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth inhibitor.

Zilberberg L, Shinkaruk S, Lequin O, Rousseau B, Hagedorn M, Costa F, Caronzolo D, Balke M, Canron X, Convert O, Laïn G, Gionnet K, Goncalvès M, Bayle M, Bello L, Chassaing G, Deleris G, Bikfalvi A.

J Biol Chem. 2003 Sep 12;278(37):35564-73. Epub 2003 Jul 1.PMID: 12837752 [PubMed - indexed for MEDLINE]Related articlesFree article

Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease.

Emerich DF, Mooney DJ, Storrie H, Babu RS, Kordower JH.

Neurotox Res. 2010 Jan;17(1):66-74. Epub 2009 Jul 9.PMID: 19588214 [PubMed - indexed for MEDLINE]Related articles

Antioxidant treatment protects striatal neurons against excitotoxic insults.

Nakao N, Grasbon-Frodl EM, Widner H, Brundin P.

Neuroscience. 1996 Jul;73(1):185-200.PMID: 8783241 [PubMed - indexed for MEDLINE]Related articles

Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats.

Figueredo-Cardenas G, Anderson KD, Chen Q, Veenman CL, Reiner A.

Exp Neurol. 1994 Sep;129(1):37-56.PMID: 7925841 [PubMed - indexed for MEDLINE]Related articles