PubMed

Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients.

de Wit M, Gennings C, Jenvey WI, Epstein SK.

Crit Care. 2008;12(3):R70. Epub 2008 May 20.PMID: 18492267 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized trial of daily awakening in critically ill patients managed with a sedation protocol: a pilot trial.

Mehta S, Burry L, Martinez-Motta JC, Stewart TE, Hallett D, McDonald E, Clarke F, Macdonald R, Granton J, Matte A, Wong C, Suri A, Cook DJ; Canadian Critical Care Trials Group.

Crit Care Med. 2008 Jul;36(7):2092-9.PMID: 18552687 [PubMed - indexed for MEDLINE]Related articles

An analgesia-delirium-sedation protocol for critically ill trauma patients reduces ventilator days and hospital length of stay.

Robinson BR, Mueller EW, Henson K, Branson RD, Barsoum S, Tsuei BJ.

J Trauma. 2008 Sep;65(3):517-26.PMID: 18784563 [PubMed - indexed for MEDLINE]Related articles

Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation.

Brook AD, Ahrens TS, Schaiff R, Prentice D, Sherman G, Shannon W, Kollef MH.

Crit Care Med. 1999 Dec;27(12):2609-15.PMID: 10628598 [PubMed - indexed for MEDLINE]Related articles

Daily interruption of sedative infusions in an adult medical-surgical intensive care unit: randomized controlled trial.

Anifantaki S, Prinianakis G, Vitsaksaki E, Katsouli V, Mari S, Symianakis A, Tassouli G, Tsaka E, Georgopoulos D.

J Adv Nurs. 2009 May;65(5):1054-60.PMID: 19399980 [PubMed - indexed for MEDLINE]Related articles

A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients.

Carson SS, Kress JP, Rodgers JE, Vinayak A, Campbell-Bright S, Levitt J, Bourdet S, Ivanova A, Henderson AG, Pohlman A, Chang L, Rich PB, Hall J.

Crit Care Med. 2006 May;34(5):1326-32.PMID: 16540958 [PubMed - indexed for MEDLINE]Related articles

The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation.

Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G.

Chest. 1998 Aug;114(2):541-8.PMID: 9726743 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial.

Girard TD, Kress JP, Fuchs BD, Thomason JW, Schweickert WD, Pun BT, Taichman DB, Dunn JG, Pohlman AS, Kinniry PA, Jackson JC, Canonico AE, Light RW, Shintani AK, Thompson JL, Gordon SM, Hall JB, Dittus RS, Bernard GR, Ely EW.

Lancet. 2008 Jan 12;371(9607):126-34.PMID: 18191684 [PubMed - indexed for MEDLINE]Related articles

Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.

Pandharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, Shintani AK, Thompson JL, Jackson JC, Deppen SA, Stiles RA, Dittus RS, Bernard GR, Ely EW.

JAMA. 2007 Dec 12;298(22):2644-53.PMID: 18073360 [PubMed - indexed for MEDLINE]Related articlesFree article

Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.

Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG; SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group.

JAMA. 2009 Feb 4;301(5):489-99. Epub 2009 Feb 2.PMID: 19188334 [PubMed - indexed for MEDLINE]Related articlesFree article

Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial.

Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister KE, Hall JB, Kress JP.

Lancet. 2009 May 30;373(9678):1874-82. Epub 2009 May 14.PMID: 19446324 [PubMed - indexed for MEDLINE]Related articles

Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay.

Marshall J, Finn CA, Theodore AC.

Crit Care Med. 2008 Feb;36(2):427-33.PMID: 18091554 [PubMed - indexed for MEDLINE]Related articles

Changing sedation practices in the intensive care unit--protocol implementation, multifaceted multidisciplinary approach and teamwork.

Arabi Y, Haddad S, Hawes R, Moore T, Pillay M, Naidu B, Issa A, Yeni B, Grant C, Alshimemeri A.

Middle East J Anesthesiol. 2007 Jun;19(2):429-47.PMID: 17684883 [PubMed - indexed for MEDLINE]Related articles

Prolonged sedation of critically ill patients with midazolam or propofol: impact on weaning and costs.

Barrientos-Vega R, Mar Sánchez-Soria M, Morales-García C, Robas-Gómez A, Cuena-Boy R, Ayensa-Rincon A.

Crit Care Med. 1997 Jan;25(1):33-40.PMID: 8989173 [PubMed - indexed for MEDLINE]Related articles

A randomized trial of protocol-directed sedation management for mechanical ventilation in an Australian intensive care unit.

Bucknall TK, Manias E, Presneill JJ.

Crit Care Med. 2008 May;36(5):1444-50.PMID: 18434914 [PubMed - indexed for MEDLINE]Related articles

Clinical sedation scores as indicators of sedative and analgesic drug exposure in intensive care unit patients.

Masica AL, Girard TD, Wilkinson GR, Thomason JW, Truman Pun B, Nair UB, Light RW, Canonico AE, Dunn J, Pandharipande P, Shintani AK, Ely EW.

Am J Geriatr Pharmacother. 2007 Sep;5(3):218-31.PMID: 17996661 [PubMed - indexed for MEDLINE]Related articles

Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit.

Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE Jr, Inouye SK, Bernard GR, Dittus RS.

JAMA. 2004 Apr 14;291(14):1753-62.PMID: 15082703 [PubMed - indexed for MEDLINE]Related articlesFree article

Propofol associated with a shorter duration of mechanical ventilation than scheduled intermittent lorazepam: a database analysis using Project IMPACT.

Fong JJ, Kanji S, Dasta JF, Garpestad E, Devlin JW.

Ann Pharmacother. 2007 Dec;41(12):1986-91. Epub 2007 Oct 23.PMID: 17956957 [PubMed - indexed for MEDLINE]Related articles

Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients.

Thomason JW, Shintani A, Peterson JF, Pun BT, Jackson JC, Ely EW.

Crit Care. 2005 Aug;9(4):R375-81. Epub 2005 Jun 1.PMID: 16137350 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497].

Breen D, Karabinis A, Malbrain M, Morais R, Albrecht S, Jarnvig IL, Parkinson P, Kirkham AJ.

Crit Care. 2005 Jun;9(3):R200-10. Epub 2005 Mar 15.PMID: 15987391 [PubMed - indexed for MEDLINE]Related articlesFree article