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A role for Numb in p53 stabilization.
Carter S, Vousden KH.
Genome Biol. 2008;9(5):221. Epub 2008 May 9. Review.
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NUMB controls p53 tumour suppressor activity.
Colaluca IN, Tosoni D, Nuciforo P, Senic-Matuglia F, Galimberti V, Viale G, Pece S, Di Fiore PP.
Nature. 2008 Jan 3;451(7174):76-80.
Numb--from flies to humans.
Yan B.
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Unequal segregation of Neuralized biases Notch activation during asymmetric cell division.
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Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.
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Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis.
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J Cell Biol. 2004 Oct 25;167(2):215-21. Epub 2004 Oct 18.
Siah-1 binds and regulates the function of Numb.
Susini L, Passer BJ, Amzallag-Elbaz N, Juven-Gershon T, Prieur S, Privat N, Tuynder M, Gendron MC, Israël A, Amson R, Oren M, Telerman A.
Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15067-72.
Interplay between Numb and Notch in epithelial cancers: role for dual oxidase maturation factor.
Ostrakhovitch EA.
Eur J Cancer. 2009 Aug;45(12):2071-6. Epub 2009 Jun 10.
The regulation of apoptosis by Numb/Notch signaling in the serotonin lineage of Drosophila.
Lundell MJ, Lee HK, Pérez E, Chadwell L.
Development. 2003 Sep;130(17):4109-21.
Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila.
O'Connor-Giles KM, Skeath JB.
Dev Cell. 2003 Aug;5(2):231-43.
Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling.
Liu L, Lanner F, Lendahl U, Das D.
Biochem Biophys Res Commun. 2011 Sep 30;413(3):426-31. Epub 2011 Aug 27.
Numb: "Adapting" notch for endocytosis.
Jafar-Nejad H, Norga K, Bellen H.
Dev Cell. 2002 Aug;3(2):155-6. Review.
aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.
Smith CA, Lau KM, Rahmani Z, Dho SE, Brothers G, She YM, Berry DM, Bonneil E, Thibault P, Schweisguth F, Le Borgne R, McGlade CJ.
EMBO J. 2007 Jan 24;26(2):468-80. Epub 2007 Jan 4.
Quantitative analysis of protein dynamics during asymmetric cell division.
Mayer B, Emery G, Berdnik D, Wirtz-Peitz F, Knoblich JA.
Curr Biol. 2005 Oct 25;15(20):1847-54.
Binary cell death decision regulated by unequal partitioning of Numb at mitosis.
Orgogozo V, Schweisguth F, Bellaïche Y.
Development. 2002 Oct;129(20):4677-84.
Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells.
Mine T, Matsueda S, Li Y, Tokumitsu H, Gao H, Danes C, Wong KK, Wang X, Ferrone S, Ioannides CG.
Cancer Immunol Immunother. 2009 Aug;58(8):1185-94. Epub 2008 Dec 2.
Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts.
Wang H, Cai Y, Chia W, Yang X.
EMBO J. 2006 Dec 13;25(24):5783-93. Epub 2006 Nov 30.
Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X.
Armbruester V, Sauter M, Roemer K, Best B, Hahn S, Nty A, Schmid A, Philipp S, Mueller A, Mueller-Lantzsch N.
J Virol. 2004 Oct;78(19):10310-9.
PARtitioning numb.
Casanova JE.
EMBO Rep. 2007 Mar;8(3):233-5. Review. No abstract available.
Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.
Bhalerao S, Berdnik D, Török T, Knoblich JA.
Curr Biol. 2005 Sep 6;15(17):1583-90.
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