My NCBISign In
RSS Settings
  • Search:

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 20 of 2990

    1.

    The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

    Tran TA, McCoy MK, Sporn MB, Tansey MG.

    J Neuroinflammation. 2008 May 12;5:14.PMID: 18474101 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

    Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS.

    FASEB J. 2005 Mar;19(3):395-7. Epub 2004 Dec 13.PMID: 15596482 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

    Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

    J Neuroinflammation. 2008 May 28;5:21.PMID: 18507839 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils.

    Thimmulappa RK, Fuchs RJ, Malhotra D, Scollick C, Traore K, Bream JH, Trush MA, Liby KT, Sporn MB, Kensler TW, Biswal S.

    Antioxid Redox Signal. 2007 Nov;9(11):1963-70.PMID: 17822364 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response.

    Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG.

    J Neurosci. 2008 Aug 20;28(34):8517-28.PMID: 18716210 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.

    Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM.

    J Neuroinflammation. 2007 Sep 19;4:23.PMID: 17880684 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

    Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS.

    J Pharmacol Exp Ther. 2003 Apr;305(1):212-8.PMID: 12649371 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).

    Yue P, Zhou Z, Khuri FR, Sun SY.

    Cancer Biol Ther. 2006 May;5(5):492-7. Epub 2006 May 2.PMID: 16582599 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Vitamin E suppression of microglial activation is neuroprotective.

    Li Y, Liu L, Barger SW, Mrak RE, Griffin WS.

    J Neurosci Res. 2001 Oct 15;66(2):163-70.PMID: 11592111 [PubMed - indexed for MEDLINE]Related articles

    10.

    Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.

    Deeb D, Gao X, Jiang H, Dulchavsky SA, Gautam SC.

    Prostate. 2009 Jun 1;69(8):851-60.PMID: 19189297 [PubMed - indexed for MEDLINE]Related articles

    11.

    Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation.

    Moon M, Kim HG, Hwang L, Seo JH, Kim S, Hwang S, Kim S, Lee D, Chung H, Oh MS, Lee KT, Park S.

    Neurotox Res. 2009 May;15(4):332-47. Epub 2009 Mar 17.PMID: 19384567 [PubMed - indexed for MEDLINE]Related articles

    12.

    c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

    Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY.

    Cancer Res. 2004 Oct 15;64(20):7570-8.PMID: 15492284 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.

    Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB.

    Clin Cancer Res. 2006 Mar 15;12(6):1828-38.PMID: 16551868 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons.

    Li FQ, Wang T, Pei Z, Liu B, Hong JS.

    J Neural Transm. 2005 Mar;112(3):331-47. Epub 2004 Oct 22.PMID: 15503194 [PubMed - indexed for MEDLINE]Related articles

    15.

    Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia.

    Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, Yang S, Hong JS.

    Brain Res Mol Brain Res. 2005 Mar 24;134(1):162-9. Epub 2004 Nov 25.PMID: 15790540 [PubMed - indexed for MEDLINE]Related articles

    16.

    Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration.

    Ralay Ranaivo H, Craft JM, Hu W, Guo L, Wing LK, Van Eldik LJ, Watterson DM.

    J Neurosci. 2006 Jan 11;26(2):662-70.PMID: 16407564 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration.

    Wang X, Chen S, Ma G, Ye M, Lu G.

    Mech Ageing Dev. 2005 Dec;126(12):1241-54. Epub 2005 Aug 19.PMID: 16112714 [PubMed - indexed for MEDLINE]Related articles

    18.

    c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.

    Zou W, Chen S, Liu X, Yue P, Sporn MB, Khuri FR, Sun SY.

    Cancer Biol Ther. 2007 Oct;6(10):1614-20. Epub 2007 Jul 19.PMID: 18253090 [PubMed - indexed for MEDLINE]Related articles

    19.

    The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production.

    Zheng LT, Hwang J, Ock J, Lee MG, Lee WH, Suk K.

    J Neurochem. 2008 Dec;107(5):1225-35. Epub 2008 Sep 11.PMID: 18786164 [PubMed - indexed for MEDLINE]Related articles

    20.

    Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation.

    Wu HM, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB.

    Neuropsychopharmacology. 2009 Sep;34(10):2344-57. Epub 2009 Jun 17.PMID: 19536110 [PubMed - indexed for MEDLINE]Related articles

    Display Settings:

    Format
    Items per page
    Sort by

    Send to:

    Choose Destination

    Supplemental Content

    Filter your results:

    Find related data

    Recent activity

    You are here: NCBI > Literature > PubMed
    Write to the Help Desk