PubMed

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.

Wang ZV, Mu J, Schraw TD, Gautron L, Elmquist JK, Zhang BB, Brownlee M, Scherer PE.

Diabetes. 2008 Aug;57(8):2137-48. Epub 2008 May 9.PMID: 18469203 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis through targeted activation of caspase 8 ("ATTAC-mice"): novel mouse models of inducible and reversible tissue ablation.

Trujillo ME, Pajvani UB, Scherer PE.

Cell Cycle. 2005 Sep;4(9):1141-5. Epub 2005 Sep 11.PMID: 16096375 [PubMed - indexed for MEDLINE]Related articlesFree article

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy.

Pajvani UB, Trujillo ME, Combs TP, Iyengar P, Jelicks L, Roth KA, Kitsis RN, Scherer PE.

Nat Med. 2005 Jul;11(7):797-803. Epub 2005 Jun 19.PMID: 15965483 [PubMed - indexed for MEDLINE]Related articles

Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.

Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I.

J Endocrinol. 2007 Apr;193(1):65-74.PMID: 17400804 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells.

Remedi MS, Nichols CG.

PLoS Med. 2008 Oct 28;5(10):e206.PMID: 18959471 [PubMed - indexed for MEDLINE]Related articlesFree article

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.

Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A.

Diabetes. 2008 Apr;57(4):938-44. Epub 2008 Jan 2.PMID: 18171713 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.

Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ.

J Biol Chem. 2003 Jan 3;278(1):471-8. Epub 2002 Oct 29.PMID: 12409292 [PubMed - indexed for MEDLINE]Related articlesFree article

Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

Gastroenterology. 2008 Mar;134(3):727-37. Epub 2008 Feb 1.PMID: 18241861 [PubMed - indexed for MEDLINE]Related articles

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

Agudo J, Ayuso E, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F.

Diabetologia. 2008 Oct;51(10):1862-72. Epub 2008 Jul 29.PMID: 18663428 [PubMed - indexed for MEDLINE]Related articles

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models.

Liadis N, Salmena L, Kwan E, Tajmir P, Schroer SA, Radziszewska A, Li X, Sheu L, Eweida M, Xu S, Gaisano HY, Hakem R, Woo M.

Diabetes. 2007 Sep;56(9):2302-11. Epub 2007 Jun 11.PMID: 17563067 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.

Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG, Butler PC.

Diabetes. 2007 May;56(5):1324-32. Epub 2007 Mar 12.PMID: 17353506 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF.

J Biol Chem. 2006 Jan 13;281(2):1159-68. Epub 2005 Nov 4.PMID: 16272563 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell failure in diabetes and preservation by clinical treatment.

Wajchenberg BL.

Endocr Rev. 2007 Apr;28(2):187-218. Epub 2007 Mar 12. Review.PMID: 17353295 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues.

Tews D, Werner U, Eckel J.

Horm Metab Res. 2008 Mar;40(3):172-80.PMID: 18348079 [PubMed - indexed for MEDLINE]Related articles

Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.

Riboulet-Chavey A, Diraison F, Siew LK, Wong FS, Rutter GA.

Diabetes. 2008 Feb;57(2):415-23. Epub 2007 Nov 14.PMID: 18003756 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effect of Astragalus polysaccharide on pancreatic cell mass in type 1 diabetic mice]

Li RJ, Qiu SD, Chen HX, Tian H, Liu GQ.

Zhongguo Zhong Yao Za Zhi. 2007 Oct;32(20):2169-73. Chinese. PMID: 18306755 [PubMed - indexed for MEDLINE]Related articles

Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.

Hamada S, Hara K, Hamada T, Yasuda H, Moriyama H, Nakayama R, Nagata M, Yokono K.

Diabetes. 2009 Jun;58(6):1321-32. Epub 2009 Mar 3.PMID: 19258434 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.

Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, Murray J, Schmidt RE, Herrera PL, Permutt MA.

Diabetologia. 2005 Nov;48(11):2313-21. Epub 2005 Oct 8.PMID: 16215705 [PubMed - indexed for MEDLINE]Related articles

Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.

Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, Butler PC.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1656-62. Epub 2007 Oct 2.PMID: 17911343 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.

Welsh M, Christmansson L, Karlsson T, Sandler S, Welsh N.

Mol Med. 1999 Mar;5(3):169-80.PMID: 10404514 [PubMed - indexed for MEDLINE]Related articlesFree article