PubMed

Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.

Costenbader KH, Chang SC, De Vivo I, Plenge R, Karlson EW.

Arthritis Res Ther. 2008;10(3):R52. Epub 2008 May 7.PMID: 18462498 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis.

Karlson EW, Chang SC, Cui J, Chibnik LB, Fraser PA, De Vivo I, Costenbader KH.

Ann Rheum Dis. 2010 Jan;69(1):54-60. Epub .PMID: 19151010 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study.

Karlson EW, Chibnik LB, Cui J, Plenge RM, Glass RJ, Maher NE, Parker A, Roubenoff R, Izmailova E, Coblyn JS, Weinblatt ME, Shadick NA.

Ann Rheum Dis. 2008 Mar;67(3):358-63. Epub 2007 Jul 31.PMID: 17666451 [PubMed - indexed for MEDLINE]Related articlesFree article

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.

Morgan AW, Thomson W, Martin SG; Yorkshire Early Arthritis Register Consortium, Carter AM; UK Rheumatoid Arthritis Genetics Consortium, Erlich HA, Barton A, Hocking L, Reid DM, Harrison P, Wordsworth P, Steer S, Worthington J, Emery P, Wilson AG, Barrett JH.

Arthritis Rheum. 2009 Sep;60(9):2565-76.PMID: 19714585 [PubMed - indexed for MEDLINE]Related articles

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.

Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, van der Helm-van Mil AH, Toes RE, Huizinga TW, Klareskog L, Alfredsson L; Epidemiological Investigation of Rheumatoid Arthritis study group.

Am J Hum Genet. 2007 May;80(5):867-75. Epub 2007 Apr 2.PMID: 17436241 [PubMed - indexed for MEDLINE]Related articlesFree article

The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden.

Kokkonen H, Johansson M, Innala L, Jidell E, Rantapää-Dahlqvist S.

Arthritis Res Ther. 2007;9(3):R56. Erratum in: Arthritis Res Ther. 2007;9(5):403. PMID: 17553139 [PubMed - indexed for MEDLINE]Related articlesFree article

Auto-antibodies, HLA and PTPN22: susceptibility markers for rheumatoid arthritis.

Orozco G, Pascual-Salcedo D, López-Nevot MA, Cobo T, Cabezón A, Martín-Mola E, Balsa A, Martín J.

Rheumatology (Oxford). 2008 Feb;47(2):138-41. Epub 2007 Dec 21.PMID: 18156150 [PubMed - indexed for MEDLINE]Related articlesFree article

The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status.

Lee AT, Li W, Liew A, Bombardier C, Weisman M, Massarotti EM, Kent J, Wolfe F, Begovich AB, Gregersen PK.

Genes Immun. 2005 Mar;6(2):129-33.PMID: 15674368 [PubMed - indexed for MEDLINE]Related articles

A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis.

Padyukov L, Silva C, Stolt P, Alfredsson L, Klareskog L.

Arthritis Rheum. 2004 Oct;50(10):3085-92.PMID: 15476204 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.

Plenge RM, Padyukov L, Remmers EF, Purcell S, Lee AT, Karlson EW, Wolfe F, Kastner DL, Alfredsson L, Altshuler D, Gregersen PK, Klareskog L, Rioux JD.

Am J Hum Genet. 2005 Dec;77(6):1044-60. Epub 2005 Nov 1.PMID: 16380915 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of PTPN22 1858T, TNFRII 196R and HLA-shared epitope alleles with rheumatoid factor and anti-citrullinated protein antibodies to very early rheumatoid arthritis diagnosis.

Goëb V, Dieudé P, Daveau R, Thomas-L'otellier M, Jouen F, Hau F, Boumier P, Tron F, Gilbert D, Fardellone P, Cornélis F, Le Loët X, Vittecoq O.

Rheumatology (Oxford). 2008 Aug;47(8):1208-12. Epub 2008 Jun 5.PMID: 18535030 [PubMed - indexed for MEDLINE]Related articles

Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women.

Criswell LA, Saag KG, Mikuls TR, Cerhan JR, Merlino LA, Lum RF, Pfeiffer KA, Woehl B, Seldin MF.

Ann Rheum Dis. 2006 Sep;65(9):1163-7. Epub 2006 Aug 3.PMID: 16887863 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma.

Majorczyk E, Jasek M, Płoski R, Wagner M, Kosior A, Pawlik A, Obojski A, Luszczek W, Nowak I, Wiśniewski A, Kuśnierczyk P.

Eur J Hum Genet. 2007 Oct;15(10):1043-8. Epub 2007 Jun 20.PMID: 17579671 [PubMed - indexed for MEDLINE]Related articlesFree article

PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease.

Johansson M, Arlestig L, Hallmans G, Rantapää-Dahlqvist S.

Arthritis Res Ther. 2006;8(1):R19.PMID: 16507117 [PubMed - indexed for MEDLINE]Related articlesFree article

Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies.

Karlson EW, Chibnik LB, Tworoger SS, Lee IM, Buring JE, Shadick NA, Manson JE, Costenbader KH.

Arthritis Rheum. 2009 Mar;60(3):641-52.PMID: 19248103 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis.

Michou L, Teixeira VH, Pierlot C, Lasbleiz S, Bardin T, Dieudé P, Prum B, Cornélis F, Petit-Teixeira E.

Ann Rheum Dis. 2008 Apr;67(4):466-70. Epub 2007 Jul 27.PMID: 17660221 [PubMed - indexed for MEDLINE]Related articles

Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations.

van Oene M, Wintle RF, Liu X, Yazdanpanah M, Gu X, Newman B, Kwan A, Johnson B, Owen J, Greer W, Mosher D, Maksymowych W, Keystone E, Rubin LA, Amos CI, Siminovitch KA.

Arthritis Rheum. 2005 Jul;52(7):1993-8.PMID: 15986374 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk of progression from undifferentiated arthritis to rheumatoid arthritis: the effect of the PTPN22 1858T-allele in anti-citrullinated peptide antibody positive patients.

Feitsma AL, Toes RE, Begovich AB, Chokkalingam AP, de Vries RR, Huizinga TW, van der Helm-van Mil AH.

Rheumatology (Oxford). 2007 Jul;46(7):1092-5. Epub 2007 Mar 6.PMID: 17341507 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.

Farragher TM, Goodson NJ, Naseem H, Silman AJ, Thomson W, Symmons D, Barton A.

Arthritis Rheum. 2008 Feb;58(2):359-69.PMID: 18240242 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific association of type 1 diabetes mellitus with anti-cyclic citrullinated peptide-positive rheumatoid arthritis.

Liao KP, Gunnarsson M, Källberg H, Ding B, Plenge RM, Padyukov L, Karlson EW, Klareskog L, Askling J, Alfredsson L.

Arthritis Rheum. 2009 Mar;60(3):653-60.PMID: 19248096 [PubMed - indexed for MEDLINE]Related articlesFree article