PubMed

Systematic review: Hydroxyurea for the treatment of adults with sickle cell disease.

Lanzkron S, Strouse JJ, Wilson R, Beach MC, Haywood C, Park H, Witkop C, Bass EB, Segal JB.

Ann Intern Med. 2008 Jun 17;148(12):939-55. Epub 2008 May 5. Review.PMID: 18458272 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydroxyurea for the treatment of sickle cell disease.

Segal JB, Strouse JJ, Beach MC, Haywood C, Witkop C, Park H, Wilson RF, Bass EB, Lanzkron S.

Evid Rep Technol Assess (Full Rep). 2008 Mar;(165):1-95. Review.PMID: 18457478 [PubMed - indexed for MEDLINE]Related articles

Hydroxyurea for sickle cell disease: a systematic review for efficacy and toxicity in children.

Strouse JJ, Lanzkron S, Beach MC, Haywood C, Park H, Witkop C, Wilson RF, Bass EB, Segal JB.

Pediatrics. 2008 Dec;122(6):1332-42. Review.PMID: 19047254 [PubMed - indexed for MEDLINE]Related articles

Hydroxyurea and sickle cell anemia. Clinical utility of a myelosuppressive "switching" agent. The Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

Charache S, Barton FB, Moore RD, Terrin ML, Steinberg MH, Dover GJ, Ballas SK, McMahon RP, Castro O, Orringer EP.

Medicine (Baltimore). 1996 Nov;75(6):300-26.PMID: 8982148 [PubMed - indexed for MEDLINE]Related articles

Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: the experience of a single center in Greece.

Loukopoulos D, Voskaridou E, Kalotychou V, Schina M, Loutradi A, Theodoropoulos I.

Blood Cells Mol Dis. 2000 Oct;26(5):453-66.PMID: 11112383 [PubMed - indexed for MEDLINE]Related articles

Three-year follow-up of hydroxyurea treatment in severely ill children with sickle cell disease. The French Study Group on Sickle Cell Disease.

de Montalembert M, Belloy M, Bernaudin F, Gouraud F, Capdeville R, Mardini R, Philippe N, Jais JP, Bardakdjian J, Ducrocq R, Maier-Redelsperger M, Elion J, Labie D, Girot R.

J Pediatr Hematol Oncol. 1997 Jul-Aug;19(4):313-8.PMID: 9256830 [PubMed - indexed for MEDLINE]Related articles

Mechanism of action of hydroxyurea in the management of sickle cell anemia in adults.

Charache S.

Semin Hematol. 1997 Jul;34(3 Suppl 3):15-21. Review.PMID: 9317197 [PubMed - indexed for MEDLINE]Related articles

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.

Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, Orringer E, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, Carlos T, Ataga K, DeCastro L, Bigelow C, Saunthararajah Y, Telfer M, Vichinsky E, Claster S, Shurin S, Bridges K, Waclawiw M, Bonds D, Terrin M.

JAMA. 2003 Apr 2;289(13):1645-51. Erratum in: JAMA. 2003 Aug 13;290(6):756. PMID: 12672732 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of hydroxyurea in children ages 2 to 5 years with sickle cell disease.

Hoppe C, Vichinsky E, Quirolo K, van Warmerdam J, Allen K, Styles L.

J Pediatr Hematol Oncol. 2000 Jul-Aug;22(4):330-4.PMID: 10959903 [PubMed - indexed for MEDLINE]Related articles

Clinical and hematologic effects of hydroxyurea in children with sickle cell anemia.

Jayabose S, Tugal O, Sandoval C, Patel P, Puder D, Lin T, Visintainer P.

J Pediatr. 1996 Oct;129(4):559-65.PMID: 8859263 [PubMed - indexed for MEDLINE]Related articles

Hydroxyurea for sickle cell disease.

Davies S, Olujohungbe A.

Cochrane Database Syst Rev. 2001;(2):CD002202. Review.PMID: 11406036 [PubMed - indexed for MEDLINE]Related articles

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

Charache S, Terrin ML, Moore RD, Dover GJ, Barton FB, Eckert SV, McMahon RP, Bonds DR.

N Engl J Med. 1995 May 18;332(20):1317-22.PMID: 7715639 [PubMed - indexed for MEDLINE]Related articlesFree article

Design of the multicenter study of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea.

Charache S, Terrin ML, Moore RD, Dover GJ, McMahon RP, Barton FB, Waclawiw M, Eckert SV.

Control Clin Trials. 1995 Dec;16(6):432-46.PMID: 8925656 [PubMed - indexed for MEDLINE]Related articles

[Hydroxyurea and other agents stimulating synthesis of fetal hemoglobin]

de Montalembert M.

Pathol Biol (Paris). 1999 Jan;47(1):55-8. Review. French. PMID: 10081780 [PubMed - indexed for MEDLINE]Related articles

Hydroxyurea in sickle cell disease patients from Eastern Saudi Arabia.

Al-Jam'a AH, Al-Dabbous IA.

Saudi Med J. 2002 Mar;23(3):277-81.PMID: 11938415 [PubMed - indexed for MEDLINE]Related articles

Hydroxyurea therapy in children severely affected with sickle cell disease.

Scott JP, Hillery CA, Brown ER, Misiewicz V, Labotka RJ.

J Pediatr. 1996 Jun;128(6):820-8.PMID: 8648542 [PubMed - indexed for MEDLINE]Related articles

Preliminary report of a toxicity study of hydroxyurea in sickle cell disease. French Study Group on Sickle Cell Disease.

de Montalembert M, Bégué P, Bernaudin F, Thuret I, Bachir D, Micheau M.

Arch Dis Child. 1999 Nov;81(5):437-9.PMID: 10519721 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term hydroxyurea treatment in young sickle cell patients.

Maier-Redelsperger M, Labie D, Elion J.

Curr Opin Hematol. 1999 Mar;6(2):115-20. Review.PMID: 10088642 [PubMed - indexed for MEDLINE]Related articles

Use of hydroxyurea in children with sickle cell disease: what comes next?

Ohene-Frempong K, Smith-Whitley K.

Semin Hematol. 1997 Jul;34(3 Suppl 3):30-41. Review.PMID: 9317199 [PubMed - indexed for MEDLINE]Related articles

Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group.

Kinney TR, Helms RW, O'Branski EE, Ohene-Frempong K, Wang W, Daeschner C, Vichinsky E, Redding-Lallinger R, Gee B, Platt OS, Ware RE.

Blood. 1999 Sep 1;94(5):1550-4.PMID: 10477679 [PubMed - indexed for MEDLINE]Related articlesFree article