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    Results: 1 to 20 of 126

    1.

    Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.

    Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, Nakagawa Y, Yahagi N, Nakakuki M, Hasty AH, Takeuchi Y, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Sone H, Yamada N.

    Diabetes. 2008 Sep;57(9):2382-92. Epub 2008 May 5.PMID: 18458149 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction.

    Shimano H, Amemiya-Kudo M, Takahashi A, Kato T, Ishikawa M, Yamada N.

    Diabetes Obes Metab. 2007 Nov;9 Suppl 2:133-9.PMID: 17919187 [PubMed - indexed for MEDLINE]Related articles

    3.

    Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.

    Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N.

    Cell Metab. 2006 Aug;4(2):143-54.PMID: 16890542 [PubMed - indexed for MEDLINE]Related articles

    4.

    Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells.

    Oberkofler H, Hafner M, Felder T, Krempler F, Patsch W.

    J Mol Med. 2009 Mar;87(3):299-306. Epub 2008 Dec 11.PMID: 19082571 [PubMed - indexed for MEDLINE]Related articles

    5.

    Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.

    Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T.

    Endocrinology. 2004 Aug;145(8):3566-77. Epub 2004 Apr 1.PMID: 15059954 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.

    Parton LE, McMillen PJ, Shen Y, Docherty E, Sharpe E, Diraison F, Briscoe CP, Rutter GA.

    Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E982-94. Epub 2006 Jun 13.PMID: 16772326 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells.

    Takahashi A, Motomura K, Kato T, Yoshikawa T, Nakagawa Y, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N, Shimano H.

    Diabetes. 2005 Feb;54(2):492-9.PMID: 15677507 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Sterol regulatory element-binding protein-1c knockdown protected INS-1E cells from lipotoxicity.

    Li J, Liu X, Ran X, Chen J, Li X, Wu W, Huang H, Huang H, Long Y, Liang J, Cheng J, Tian H.

    Diabetes Obes Metab. 2009 Sep 16. [Epub ahead of print]PMID: 19758361 [PubMed - as supplied by publisher]Related articles

    9.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease.

    Kohjima M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, Fujino T, Yada M, Yada R, Harada N, Enjoji M, Takayanagi R, Nakamuta M.

    Int J Mol Med. 2008 Apr;21(4):507-11.PMID: 18360697 [PubMed - indexed for MEDLINE]Related articles

    11.

    Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.

    Matsumoto M, Ogawa W, Teshigawara K, Inoue H, Miyake K, Sakaue H, Kasuga M.

    Diabetes. 2002 Jun;51(6):1672-80.PMID: 12031952 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling.

    Shimano H.

    J Mol Med. 2007 May;85(5):437-44. Epub 2007 Feb 6. Review.PMID: 17279346 [PubMed - indexed for MEDLINE]Related articles

    13.

    Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors.

    Li X, Hansen PA, Xi L, Chandraratna RA, Burant CF.

    J Biol Chem. 2005 Nov 18;280(46):38317-27. Epub 2005 Sep 22.PMID: 16179348 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.

    Zitzer H, Wente W, Brenner MB, Sewing S, Buschard K, Gromada J, Efanov AM.

    Endocrinology. 2006 Aug;147(8):3898-905. Epub 2006 Apr 27.PMID: 16644917 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effect of exercise and insulin on SREBP-1c expression in human skeletal muscle: potential roles for the ERK1/2 and Akt signalling pathways.

    Boonsong T, Norton L, Chokkalingam K, Jewell K, Macdonald I, Bennett A, Tsintzas K.

    Biochem Soc Trans. 2007 Nov;35(Pt 5):1310-1.PMID: 17956338 [PubMed - indexed for MEDLINE]Related articles

    16.

    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

    Diraison F, Parton L, Ferré P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA.

    Biochem J. 2004 Mar 15;378(Pt 3):769-78.PMID: 14690455 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

    Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

    J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.PMID: 19363290 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.

    Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM 2nd, Siddiqi SA, Park EA, Raghow R, Elam MB.

    J Biol Chem. 2009 Mar 20;284(12):7518-32. Epub 2009 Jan 21.PMID: 19158095 [PubMed - indexed for MEDLINE]Related articles

    19.

    Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

    Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V.

    Diabetes. 2009 Sep;58(9):2048-58. Epub 2009 Jun 5.PMID: 19502418 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.

    Mur C, Arribas M, Benito M, Valverde AM.

    Endocrinology. 2003 Feb;144(2):581-93.PMID: 12538620 [PubMed - indexed for MEDLINE]Related articlesFree article

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