PubMed

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.

Diabetes. 2008 Aug;57(8):1999-2011. Epub 2008 May 5.PMID: 18458147 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.PMID: 17584959 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists.

Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE.

J Biol Chem. 2006 Feb 3;281(5):2654-60. Epub 2005 Dec 2.PMID: 16326714 [PubMed - indexed for MEDLINE]Related articlesFree article

Pan-PPAR agonist beneficial effects in overweight mice fed a high-fat high-sucrose diet.

Fernandes-Santos C, Carneiro RE, de Souza Mendonca L, Aguila MB, Mandarim-de-Lacerda CA.

Nutrition. 2009 Jul-Aug;25(7-8):818-27. Epub 2009 Mar 5.PMID: 19268533 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination.

Tsuchida A, Yamauchi T, Takekawa S, Hada Y, Ito Y, Maki T, Kadowaki T.

Diabetes. 2005 Dec;54(12):3358-70.PMID: 16306350 [PubMed - indexed for MEDLINE]Related articlesFree article

Cilostazol ameliorates metabolic abnormalities with suppression of proinflammatory markers in a db/db mouse model of type 2 diabetes via activation of peroxisome proliferator-activated receptor gamma transcription.

Park SY, Shin HK, Lee JH, Kim CD, Lee WS, Rhim BY, Hong KW.

J Pharmacol Exp Ther. 2009 May;329(2):571-9. Epub 2009 Feb 12.PMID: 19221061 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway.

Díaz-Delfín J, Morales M, Caelles C.

Diabetes. 2007 Jul;56(7):1865-71. Epub 2007 Apr 6.PMID: 17416798 [PubMed - indexed for MEDLINE]Related articlesFree article

n-3 fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet.

Kuda O, Jelenik T, Jilkova Z, Flachs P, Rossmeisl M, Hensler M, Kazdova L, Ogston N, Baranowski M, Gorski J, Janovska P, Kus V, Polak J, Mohamed-Ali V, Burcelin R, Cinti S, Bryhn M, Kopecky J.

Diabetologia. 2009 May;52(5):941-51. Epub 2009 Mar 11. Erratum in: Diabetologia. 2009 Jul;52(7):1455. PMID: 19277604 [PubMed - indexed for MEDLINE]Related articles

Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats.

Kramer D, Shapiro R, Adler A, Bush E, Rondinone CM.

Metabolism. 2001 Nov;50(11):1294-300.PMID: 11699047 [PubMed - indexed for MEDLINE]Related articles

Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production.

Hoo RL, Chow WS, Yau MH, Xu A, Tso AW, Tse HF, Fong CH, Tam S, Chan L, Lam KS.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2777-82. Epub 2007 Oct 11.PMID: 17932317 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.

Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M.

Endocrinology. 2006 Sep;147(9):4517-24. Epub 2006 Jun 1.PMID: 16740970 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation.

Hansmann G, Wagner RA, Schellong S, Perez VA, Urashima T, Wang L, Sheikh AY, Suen RS, Stewart DJ, Rabinovitch M.

Circulation. 2007 Mar 13;115(10):1275-84. Epub 2007 Mar 5.PMID: 17339547 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle.

Perreault M, Marette A.

Nat Med. 2001 Oct;7(10):1138-43.PMID: 11590438 [PubMed - indexed for MEDLINE]Related articles

Weight-loss-associated induction of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma correlate with reduced atherosclerosis and improved cardiovascular function in obese insulin-resistant mice.

Verreth W, De Keyzer D, Pelat M, Verhamme P, Ganame J, Bielicki JK, Mertens A, Quarck R, Benhabilès N, Marguerie G, Mackness B, Mackness M, Ninio E, Herregods MC, Balligand JL, Holvoet P.

Circulation. 2004 Nov 16;110(20):3259-69. Epub 2004 Nov 8.PMID: 15533870 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo.

Nakano R, Kurosaki E, Yoshida S, Yokono M, Shimaya A, Maruyama T, Shibasaki M.

Biochem Pharmacol. 2006 Jun 28;72(1):42-52. Epub 2006 Apr 7.PMID: 16696951 [PubMed - indexed for MEDLINE]Related articles

Effect of PPAR-alpha and -gamma agonist on the expression of visfatin, adiponectin, and TNF-alpha in visceral fat of OLETF rats.

Choi KC, Ryu OH, Lee KW, Kim HY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):747-53.PMID: 16157299 [PubMed - indexed for MEDLINE]Related articles

Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression.

Kanatani Y, Usui I, Ishizuka K, Bukhari A, Fujisaka S, Urakaze M, Haruta T, Kishimoto T, Naka T, Kobayashi M.

Diabetes. 2007 Mar;56(3):795-803.PMID: 17327450 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality.

Minge CE, Bennett BD, Norman RJ, Robker RL.

Endocrinology. 2008 May;149(5):2646-56. Epub 2008 Feb 14.PMID: 18276752 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.

Carvalho-Filho MA, Ueno M, Carvalheira JB, Velloso LA, Saad MJ.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E476-82. Epub 2006 Apr 25.PMID: 16638822 [PubMed - indexed for MEDLINE]Related articlesFree article

FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue.

Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM.

Diabetes. 2009 Jun;58(6):1275-82. Epub 2009 Mar 16.PMID: 19289458 [PubMed - indexed for MEDLINE]Related articlesFree article