PubMed

Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice.

Vlad G, D'Agati VD, Zhang QY, Liu Z, Ho EK, Mohanakumar T, Hardy MA, Cortesini R, Suciu-Foca N.

Diabetes. 2008 Jul;57(7):1878-86. Epub 2008 Apr 16.PMID: 18420485 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in the contribution of CD4+ T cells to proislet and islet allograft rejection correlate with constitutive class II MHC alloantigen expression.

Simeonovic CJ, Brown DJ, Townsend MJ, Wilson JD.

Cell Transplant. 1996 Sep-Oct;5(5):525-41.PMID: 8889212 [PubMed - indexed for MEDLINE]Related articles

Human peripheral blood lymphocyte reconstituted severe combined immunodeficient (hu-PBL-SCID) mice. A model for human islet allograft rejection.

Shiroki R, Poindexter NJ, Woodle ES, Hussain MS, Mohanakumar T, Scharp DW.

Transplantation. 1994 Jun 15;57(11):1555-62.PMID: 8009588 [PubMed - indexed for MEDLINE]Related articles

Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic nod mice from autoimmune destruction and allogeneic and xenogeneic graft rejection.

Guo Z, Wu T, Kirchhof N, Mital D, Williams JW, Azuma M, Sutherland DE, Hering BJ.

Transplantation. 2001 Jun 15;71(11):1656-65.PMID: 11435979 [PubMed - indexed for MEDLINE]Related articles

Anti-LFA-1 improves pig islet xenograft function in diabetic mice when long-term acceptance is induced by CTLA4Ig/anti-CD40L.

Kumagai-Braesch M, Ekberg H, Wang F, Osterholm C, Ehrnfelt C, Sharma A, Lindeborg E, Holgersson J, Corbascio M.

Transplantation. 2007 May 15;83(9):1259-67.PMID: 17496544 [PubMed - indexed for MEDLINE]Related articles

In vitro xenorecognition of adult pig pancreatic islet cells by splenocytes from nonobese diabetic or non-diabetes-prone mice.

Rivereau AS, You S, Lalain S, Gouin E, Saï P.

Transplantation. 1998 Sep 15;66(5):633-8.PMID: 9753345 [PubMed - indexed for MEDLINE]Related articles

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation.

Molano RD, Berney T, Li H, Cattan P, Pileggi A, Vizzardelli C, Kenyon NS, Ricordi C, Burkly LC, Inverardi L.

Diabetes. 2001 Feb;50(2):270-6.PMID: 11272136 [PubMed - indexed for MEDLINE]Related articlesFree article

Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.

Suarez-Pinzon W, Rajotte RV, Mosmann TR, Rabinovitch A.

Diabetes. 1996 Oct;45(10):1350-7.PMID: 8826970 [PubMed - indexed for MEDLINE]Related articles

Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.

Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R.

J Immunol. 2007 Jun 1;178(11):7432-41.PMID: 17513794 [PubMed - indexed for MEDLINE]Related articlesFree article

Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.

Banuelos SJ, Shultz LD, Greiner DL, Burzenski LM, Gott B, Lyons BL, Rossini AA, Appel MC.

Clin Immunol. 2004 Sep;112(3):273-83.PMID: 15308121 [PubMed - indexed for MEDLINE]Related articles

Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo.

Utsugi T, Yoon JW, Park BJ, Imamura M, Averill N, Kawazu S, Santamaria P.

Diabetes. 1996 Aug;45(8):1121-31.PMID: 8690161 [PubMed - indexed for MEDLINE]Related articles

Pancreatic islet xenograft tolerance after short-term costimulation blockade is associated with increased CD4+ T cell apoptosis but not immune deviation.

Lehnert AM, Yi S, Burgess JS, O'Connell PJ.

Transplantation. 2000 Mar 27;69(6):1176-85.PMID: 10762224 [PubMed - indexed for MEDLINE]Related articles

Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.

Solomon M, Flodström-Tullberg M, Sarvetnick N.

Transplantation. 2005 May 15;79(9):1104-9.PMID: 15880051 [PubMed - indexed for MEDLINE]Related articles

Rejection of porcine islet xenografts mediated by CD4+ T cells activated through the indirect antigen recognition pathway.

Olack BJ, Jaramillo A, Benshoff ND, Kaleem Z, Swanson CJ, Lowell JA, Mohanakumar T.

Xenotransplantation. 2002 Nov;9(6):393-401.PMID: 12371935 [PubMed - indexed for MEDLINE]Related articles

Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice.

Makhlouf L, Grey ST, Dong V, Csizmadia E, Arvelo MB, Auchincloss H Jr, Ferran C, Sayegh MH.

Transplantation. 2004 Apr 15;77(7):990-7.PMID: 15087759 [PubMed - indexed for MEDLINE]Related articles

Locally expressed CTLA4-Ig in a pancreatic beta-cell line suppresses accelerated graft rejection response induced by donor-specific transfusion.

Kimura F, Gotoh M, Tanaka T, Luo Z, Miyazaki J, Uede T, Monden M, Miyasaka M.

Diabetologia. 2002 Jun;45(6):831-40. Epub 2002 May 25.PMID: 12107727 [PubMed - indexed for MEDLINE]Related articles

Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice.

Drage M, Zaccone P, Phillips JM, Nicoletti F, Dawson J, Andrew Bradley J, Cooke A.

Transplantation. 2002 Sep 15;74(5):611-9.PMID: 12352875 [PubMed - indexed for MEDLINE]Related articles

Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice.

Wagar EJ, Cromwell MA, Shultz LD, Woda BA, Sullivan JL, Hesselton RM, Greiner DL.

J Immunol. 2000 Jul 1;165(1):518-27.PMID: 10861091 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid destruction of encapsulated islet xenografts by NOD mice is CD4-dependent and facilitated by B-cells: innate immunity and autoimmunity do not play significant roles.

Xu BY, Yang H, Serreze DV, MacIntosh R, Yu W, Wright JR Jr.

Transplantation. 2005 Aug 15;80(3):402-9.PMID: 16082337 [PubMed - indexed for MEDLINE]Related articles

Inhibition of transplant rejection by pretreatment of xenogeneic pancreatic islet cells with anti-ICAM-1 antibodies.

Zeng Y, Gage A, Montag A, Rothlein R, Thistlethwaite JR, Bluestone JA.

Transplantation. 1994 Sep 27;58(6):681-9.PMID: 7940687 [PubMed - indexed for MEDLINE]Related articles