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    Results: 1 to 20 of 354

    1.

    Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid.

    Nichol KE, Poon WW, Parachikova AI, Cribbs DH, Glabe CG, Cotman CW.

    J Neuroinflammation. 2008 Apr 9;5:13.PMID: 18400101 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide.

    Townsend KP, Town T, Mori T, Lue LF, Shytle D, Sanberg PR, Morgan D, Fernandez F, Flavell RA, Tan J.

    Eur J Immunol. 2005 Mar;35(3):901-10.PMID: 15688347 [PubMed - indexed for MEDLINE]Related articles

    3.

    Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology.

    Mehlhorn G, Hollborn M, Schliebs R.

    Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):423-31.PMID: 10817926 [PubMed - indexed for MEDLINE]Related articles

    4.

    Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease.

    Jin JJ, Kim HD, Maxwell JA, Li L, Fukuchi K.

    J Neuroinflammation. 2008 May 29;5:23.PMID: 18510752 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse.

    Nichol KE, Parachikova AI, Cotman CW.

    Behav Brain Res. 2007 Dec 3;184(2):124-32. Epub 2007 Jul 10.PMID: 17698211 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease.

    Yuede CM, Zimmerman SD, Dong H, Kling MJ, Bero AW, Holtzman DM, Timson BF, Csernansky JG.

    Neurobiol Dis. 2009 Sep;35(3):426-32. Epub 2009 Jun 12.PMID: 19524672 [PubMed - indexed for MEDLINE]Related articles

    7.

    Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease.

    Sly LM, Krzesicki RF, Brashler JR, Buhl AE, McKinley DD, Carter DB, Chin JE.

    Brain Res Bull. 2001 Dec;56(6):581-8.PMID: 11786245 [PubMed - indexed for MEDLINE]Related articles

    8.

    Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.

    Yamamoto M, Kiyota T, Horiba M, Buescher JL, Walsh SM, Gendelman HE, Ikezu T.

    Am J Pathol. 2007 Feb;170(2):680-92.PMID: 17255335 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology.

    Münch G, Apelt J, Rosemarie-Kientsch-Engel, Stahl P, Lüth HJ, Schliebs R.

    J Neurochem. 2003 Jul;86(2):283-9.PMID: 12871569 [PubMed - indexed for MEDLINE]Related articles

    10.

    Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease.

    Handattu SP, Garber DW, Monroe CE, van Groen T, Kadish I, Nayyar G, Cao D, Palgunachari MN, Li L, Anantharamaiah GM.

    Neurobiol Dis. 2009 Jun;34(3):525-34. Epub 2009 Apr 1.PMID: 19344763 [PubMed - indexed for MEDLINE]Related articles

    11.

    Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition.

    Parachikova A, Nichol KE, Cotman CW.

    Neurobiol Dis. 2008 Apr;30(1):121-9. Epub 2008 Jan 5.PMID: 18258444 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice.

    Petrushina I, Ghochikyan A, Mkrtichyan M, Mamikonyan G, Movsesyan N, Ajdari R, Vasilevko V, Karapetyan A, Lees A, Agadjanyan MG, Cribbs DH.

    J Neuroinflammation. 2008 Sep 29;5:42.PMID: 18823564 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice.

    Nikolic WV, Hou H, Town T, Zhu Y, Giunta B, Sanberg CD, Zeng J, Luo D, Ehrhart J, Mori T, Sanberg PR, Tan J.

    Stem Cells Dev. 2008 Jun;17(3):423-39.PMID: 18366296 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.

    Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J.

    Neurobiol Dis. 2008 Feb;29(2):336-53. Epub 2007 Oct 16.PMID: 18055209 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology.

    Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA.

    Nat Med. 2008 Jun;14(6):681-7. Epub 2008 Jun 1.PMID: 18516051 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Ginger extract inhibits beta-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes.

    Grzanna R, Phan P, Polotsky A, Lindmark L, Frondoza CG.

    J Altern Complement Med. 2004 Dec;10(6):1009-13.PMID: 15673995 [PubMed - indexed for MEDLINE]Related articles

    17.

    Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease.

    Olcese JM, Cao C, Mori T, Mamcarz MB, Maxwell A, Runfeldt MJ, Wang L, Zhang C, Lin X, Zhang G, Arendash GW.

    J Pineal Res. 2009 Aug;47(1):82-96. Epub 2009 Jun 17.PMID: 19538338 [PubMed - indexed for MEDLINE]Related articles

    18.

    Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.

    Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA.

    J Neurosci. 2008 Jun 18;28(25):6333-41.PMID: 18562603 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease.

    Monsonego A, Imitola J, Petrovic S, Zota V, Nemirovsky A, Baron R, Fisher Y, Owens T, Weiner HL.

    Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5048-53. Epub 2006 Mar 20.PMID: 16549802 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.

    Culbert AA, Skaper SD, Howlett DR, Evans NA, Facci L, Soden PE, Seymour ZM, Guillot F, Gaestel M, Richardson JC.

    J Biol Chem. 2006 Aug 18;281(33):23658-67. Epub 2006 Jun 14.PMID: 16774924 [PubMed - indexed for MEDLINE]Related articlesFree article

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