PubMed

Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice.

Levisetti MG, Lewis DM, Suri A, Unanue ER.

Diabetes. 2008 Jul;57(7):1852-60. Epub 2008 Apr 8.PMID: 18398138 [PubMed - indexed for MEDLINE]Related articlesFree article

A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice.

Harrison LC, Honeyman MC, Trembleau S, Gregori S, Gallazzi F, Augstein P, Brusic V, Hammer J, Adorini L.

J Exp Med. 1997 Mar 17;185(6):1013-21.PMID: 9091575 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous T-cell proliferation in the non-obese diabetic mouse to a peptide from the unique class II MHC molecule, I-Ag7, which is also protective against the development of autoimmune diabetes.

Xu XJ, Gearon C, Stevens E, Vergani D, Baum H, Peakman M.

Diabetologia. 1999 May;42(5):560-5.PMID: 10333048 [PubMed - indexed for MEDLINE]Related articles

IL-12 administration reveals diabetogenic T cells in genetically resistant I-Ealpha-transgenic nonobese diabetic mice: resistance to autoimmune diabetes is associated with binding of Ealpha-derived peptides to the I-A(g7) molecule.

Trembleau S, Gregori S, Penna G, Gorny I, Adorini L.

J Immunol. 2001 Oct 1;167(7):4104-14.PMID: 11564833 [PubMed - indexed for MEDLINE]Related articlesFree article

A peptide binding motif for I-Eg7, the MHC class II molecule that protects E alpha-transgenic nonobese diabetic mice from autoimmune diabetes.

Gregori S, Trembleau S, Penna G, Gallazzi F, Hammer J, Papadopoulos GK, Adorini L.

J Immunol. 1999 Jun 1;162(11):6630-40.PMID: 10352280 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin.

Griffin AC, Zhao W, Wegmann KW, Hickley WF.

Am J Pathol. 1995 Sep;147(3):845-57.PMID: 7545875 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes.

Chen W, Bergerot I, Elliott JF, Harrison LC, Abiru N, Eisenbarth GS, Delovitch TL.

J Immunol. 2001 Nov 1;167(9):4926-35.PMID: 11673498 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response.

Ridgway WM, Ito H, Fassò M, Yu C, Fathman CG.

J Exp Med. 1998 Dec 21;188(12):2267-75.PMID: 9858513 [PubMed - indexed for MEDLINE]Related articlesFree article

A self MHC class II beta-chain peptide prevents diabetes in nonobese diabetic mice.

Chaturvedi P, Agrawal B, Zechel M, Lee-Chan E, Singh B.

J Immunol. 2000 Jun 15;164(12):6610-20.PMID: 10843721 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire.

Chao CC, Sytwu HK, Chen EL, Toma J, McDevitt HO.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9299-304. Erratum in: Proc Natl Acad Sci U S A 1999 Oct 26;96(22):12970. PMID: 10430937 [PubMed - indexed for MEDLINE]Related articlesFree article

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide.

Martinez NR, Augstein P, Moustakas AK, Papadopoulos GK, Gregori S, Adorini L, Jackson DC, Harrison LC.

J Clin Invest. 2003 May;111(9):1365-71.PMID: 12727928 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.

James EA, Kwok WW.

Diabetes. 2008 Jul;57(7):1788-9. No abstract available. PMID: 18586912 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of type 1 diabetes by a self-MHC class II peptide: role of transforming growth factor beta (TGF-beta).

Mukherjee R, Chaturvedi P, Agrawal B, Singh B.

Cell Mol Biol (Noisy-le-grand). 2003 Mar;49(2):159-69.PMID: 12887099 [PubMed - indexed for MEDLINE]Related articles

T-splenocytes from non-obese diabetic mice binding to xenogeneic pancreatic beta-cells in vitro. Implication of the alpha/beta T-cell receptor and of major histocompatibility complex class II molecules from target cells.

Martignat L, Feve B, Ouary M, Pogu S, Charbonnel B, Saï P.

J Autoimmun. 1993 Dec;6(6):753-69.PMID: 8155255 [PubMed - indexed for MEDLINE]Related articles

Relative resistance to nasally induced tolerance in non-obese diabetic mice but not other I-A(g7)-expressing mouse strains.

Quinn A, Melo M, Ethell D, Sercarz EE.

Int Immunol. 2001 Oct;13(10):1321-33.PMID: 11581177 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction.

Kanagawa O, Martin SM, Vaupel BA, Carrasco-Marin E, Unanue ER.

Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1721-4.PMID: 9465083 [PubMed - indexed for MEDLINE]Related articlesFree article

Self-peptides that bind with low affinity to the diabetes-associated I-A(g7) molecule readily induce T cell tolerance in non-obese diabetic mice.

Ferlin WG, Mougneau E, Hugues S, Appel H, Jang MH, Cazareth J, Beaudoin L, Schricke C, Lehuen A, Wucherpfennig KW, Glaichenhaus N.

Eur J Immunol. 2004 Oct;34(10):2656-63.PMID: 15368281 [PubMed - indexed for MEDLINE]Related articles

Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes.

Mukherjee R, Wagar D, Stephens TA, Lee-Chan E, Singh B.

J Immunol. 2005 May 1;174(9):5306-15.PMID: 15843527 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes.

Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P.

Diabetes. 2002 Feb;51(2):325-38.PMID: 11812739 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional consequences of the binding of MHC class II-derived peptides to MHC class II.

Feili-Hariri M, Kao H, Mietzner TA, Morel PA.

Int Immunol. 1996 Dec;8(12):1857-65.PMID: 8982770 [PubMed - indexed for MEDLINE]Related articlesFree article