PubMed

The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice.

Emamaullee JA, Davis J, Pawlick R, Toso C, Merani S, Cai SX, Tseng B, Shapiro AM.

Diabetes. 2008 Jun;57(6):1556-66. Epub 2008 Mar 20.PMID: 18356409 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation.

Emamaullee JA, Stanton L, Schur C, Shapiro AM.

Diabetes. 2007 May;56(5):1289-98. Epub 2007 Feb 15.PMID: 17303806 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft.

Montolio M, Téllez N, Biarnés M, Soler J, Montanya E.

Cell Transplant. 2005;14(1):59-65.PMID: 15789663 [PubMed - indexed for MEDLINE]Related articles

Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice.

Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N.

Diabetes. 2007 May;56(5):1259-67. Epub 2007 Feb 7.PMID: 17287463 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor.

Noguchi H, Nakai Y, Ueda M, Masui Y, Futaki S, Kobayashi N, Hayashi S, Matsumoto S.

Diabetologia. 2007 Mar;50(3):612-9. Epub 2007 Jan 16.PMID: 17225125 [PubMed - indexed for MEDLINE]Related articles

Inhibition of angiogenesis is associated with reduced islet engraftment in diabetic recipient mice.

Zhang N, Qu S, Xu J, Bromberg JS, Dong HH.

Transplant Proc. 2005 Dec;37(10):4452-7.PMID: 16387144 [PubMed - indexed for MEDLINE]Related articles

Liraglutide, a long-acting human glucagon-like peptide 1 analog, improves glucose homeostasis in marginal mass islet transplantation in mice.

Merani S, Truong W, Emamaullee JA, Toso C, Knudsen LB, Shapiro AM.

Endocrinology. 2008 Sep;149(9):4322-8. Epub 2008 May 29.PMID: 18511515 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 does not promote Beta-cell proliferation or survival during the early post-islet transplant period in mice.

Crutchlow MF, Yu M, Bae YS, Deng S, Stoffers DA.

Transplant Proc. 2008 Jun;40(5):1650-7. Erratum in: Transplant Proc. 2009 Jan-Feb;41(1):450. PMID: 18589167 [PubMed - indexed for MEDLINE]Related articlesFree article

Porcine islet graft function is affected by pretreatment with a caspase-3 inhibitor.

Brandhorst D, Kumarasamy V, Maatoui A, Alt A, Bretzel RG, Brandhorst H.

Cell Transplant. 2006;15(4):311-7.PMID: 16898224 [PubMed - indexed for MEDLINE]Related articles

Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice.

Rao P, Roccisana J, Takane KK, Bottino R, Zhao A, Trucco M, García-Ocaña A.

Diabetes. 2005 Jun;54(6):1664-75.PMID: 15919787 [PubMed - indexed for MEDLINE]Related articlesFree article

Compaction of islets is detrimental to transplant outcome in mice.

Merani S, Schur C, Truong W, Knutzen VK, Lakey JR, Anderson CC, Ricordi C, Shapiro AM.

Transplantation. 2006 Dec 15;82(11):1472-6.PMID: 17164719 [PubMed - indexed for MEDLINE]Related articles

New mouse model to study islet transplantation in insulin-dependent diabetes mellitus.

Mathews CE, Langley SH, Leiter EH.

Transplantation. 2002 Apr 27;73(8):1333-6.PMID: 11981430 [PubMed - indexed for MEDLINE]Related articles

The role of macrophage migration inhibitory factor in mouse islet transplantation.

Toso C, Serre-Beinier V, Emamaullee J, Merani S, Armanet M, Wojtusciszyn A, Bosco D, Calandra T, Roger T, Morel P, Shapiro AM, Berney T.

Transplantation. 2008 Nov 27;86(10):1361-9.PMID: 19034004 [PubMed - indexed for MEDLINE]Related articles

Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species.

Li X, Chen H, Epstein PN.

J Biol Chem. 2004 Jan 2;279(1):765-71. Epub 2003 Oct 23.PMID: 14576162 [PubMed - indexed for MEDLINE]Related articlesFree article

Successful islet transplantation: continued insulin reserve provides long-term glycemic control.

Ryan EA, Lakey JR, Paty BW, Imes S, Korbutt GS, Kneteman NM, Bigam D, Rajotte RV, Shapiro AM.

Diabetes. 2002 Jul;51(7):2148-57.PMID: 12086945 [PubMed - indexed for MEDLINE]Related articlesFree article

Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide.

Emamaullee JA, Merani S, Toso C, Kin T, Al-Saif F, Truong W, Pawlick R, Davis J, Edgar R, Lock J, Bonner-Weir S, Knudsen LB, Shapiro AM.

Endocrinology. 2009 May;150(5):2145-52. Epub 2009 Jan 8.PMID: 19131571 [PubMed - indexed for MEDLINE]Related articles

The efficacy and toxicity of rapamycin in murine islet transplantation. In vitro and in vivo studies.

Fabian MC, Lakey JR, Rajotte RV, Kneteman NM.

Transplantation. 1993 Nov;56(5):1137-42.PMID: 8249114 [PubMed - indexed for MEDLINE]Related articles

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

Zhang YC, Molano RD, Pileggi A, Powers M, Cross J, Wasserfall C, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Flotte T, Ellis TM, Ricordi C, Atkinson MA, Inverardi L.

Transplantation. 2002 Oct 27;74(8):1184-6.PMID: 12438968 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts.

Nakano M, Yasunami Y, Maki T, Kodama S, Ikehara Y, Nakamura T, Tanaka M, Ikeda S.

Transplantation. 2000 Jan 27;69(2):214-21.PMID: 10670629 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of nerve growth factor on islet transplantation.

Miao G, Mace J, Kirby M, Hopper A, Peverini R, Chinnock R, Shapiro J, Hathout E.

Transplant Proc. 2005 Oct;37(8):3490-2.PMID: 16298638 [PubMed - indexed for MEDLINE]Related articles