PubMed

Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells.

Liu X, Mameza MG, Lee YS, Eseonu CI, Yu CR, Kang Derwent JJ, Egwuagu CE.

Diabetes. 2008 Jun;57(6):1651-8. Epub 2008 Mar 20.PMID: 18356406 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection.

Rønn SG, Börjesson A, Bruun C, Heding PE, Frobøse H, Mandrup-Poulsen T, Karlsen AE, Rasschaert J, Sandler S, Billestrup N.

Diabetologia. 2008 Oct;51(10):1873-82. Epub 2008 Jul 22.PMID: 18648765 [PubMed - indexed for MEDLINE]Related articles

Reciprocal regulation of SOCS 1 and SOCS3 enhances resistance to ionizing radiation in glioblastoma multiforme.

Zhou H, Miki R, Eeva M, Fike FM, Seligson D, Yang L, Yoshimura A, Teitell MA, Jamieson CA, Cacalano NA.

Clin Cancer Res. 2007 Apr 15;13(8):2344-53.PMID: 17438093 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine-induced SOCS expression is inhibited by cAMP analogue: impact on regeneration in injured retina.

Park KK, Hu Y, Muhling J, Pollett MA, Dallimore EJ, Turnley AM, Cui Q, Harvey AR.

Mol Cell Neurosci. 2009 Jul;41(3):313-24. Epub 2009 Apr 24.PMID: 19394427 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells.

Yu CR, Mahdi RM, Ebong S, Vistica BP, Gery I, Egwuagu CE.

J Biol Chem. 2003 Aug 8;278(32):29752-9. Epub 2003 Jun 2.PMID: 12783879 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-alpha-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins.

Zimmerer JM, Lesinski GB, Kondadasula SV, Karpa VI, Lehman A, Raychaudhury A, Becknell B, Carson WE 3rd.

J Immunol. 2007 Apr 15;178(8):4832-45.PMID: 17404264 [PubMed - indexed for MEDLINE]Related articlesFree article

The dual function of hepatic SOCS3 in insulin resistance in vivo.

Torisu T, Sato N, Yoshiga D, Kobayashi T, Yoshioka T, Mori H, Iida M, Yoshimura A.

Genes Cells. 2007 Feb;12(2):143-54.PMID: 17295835 [PubMed - indexed for MEDLINE]Related articles

Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.

Evans MK, Yu CR, Lohani A, Mahdi RM, Liu X, Trzeciak AR, Egwuagu CE.

Oncogene. 2007 Mar 22;26(13):1941-8. Epub 2006 Sep 25.PMID: 17001312 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA.

J Biol Chem. 2003 Apr 18;278(16):13740-6. Epub 2003 Jan 30.PMID: 12560330 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling.

van de Geijn GJ, Gits J, Touw IP.

J Leukoc Biol. 2004 Jul;76(1):237-44. Epub 2004 Apr 23.PMID: 15107455 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling.

Ben-Zvi T, Yayon A, Gertler A, Monsonego-Ornan E.

J Cell Sci. 2006 Jan 15;119(Pt 2):380-7.PMID: 16410555 [PubMed - indexed for MEDLINE]Related articlesFree article

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.

Rui L, Yuan M, Frantz D, Shoelson S, White MF.

J Biol Chem. 2002 Nov 1;277(44):42394-8. Epub 2002 Sep 12.PMID: 12228220 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses.

Ding Y, Chen D, Tarcsafalvi A, Su R, Qin L, Bromberg JS.

J Immunol. 2003 Feb 1;170(3):1383-91.PMID: 12538698 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance.

Egwuagu CE, Yu CR, Zhang M, Mahdi RM, Kim SJ, Gery I.

J Immunol. 2002 Apr 1;168(7):3181-7.PMID: 11907070 [PubMed - indexed for MEDLINE]Related articlesFree article

The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling.

Wormald S, Zhang JG, Krebs DL, Mielke LA, Silver J, Alexander WS, Speed TP, Nicola NA, Hilton DJ.

J Biol Chem. 2006 Apr 21;281(16):11135-43. Epub 2006 Feb 10.PMID: 16473883 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling.

Bayle J, Letard S, Frank R, Dubreuil P, De Sepulveda P.

J Biol Chem. 2004 Mar 26;279(13):12249-59. Epub 2004 Jan 5.PMID: 14707129 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of SOCS3 in monocytes and SOCS1 in lymphocytes correlates with progressive loss of renal function and cardiovascular risk factors in chronic kidney disease.

Rastmanesh MM, Bluyssen HA, Joles JA, Boer P, Willekes N, Braam B.

Eur J Pharmacol. 2008 Sep 28;593(1-3):99-104. Epub 2008 Jul 12.PMID: 18656467 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.

Shi H, Tzameli I, Bjørbaek C, Flier JS.

J Biol Chem. 2004 Aug 13;279(33):34733-40. Epub 2004 Jun 4.PMID: 15181014 [PubMed - indexed for MEDLINE]Related articlesFree article

Attenuation of leptin and insulin signaling by SOCS proteins.

Howard JK, Flier JS.

Trends Endocrinol Metab. 2006 Nov;17(9):365-71. Epub 2006 Sep 28. Review.PMID: 17010638 [PubMed - indexed for MEDLINE]Related articles

Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors.

Ebong S, Yu CR, Carper DA, Chepelinsky AB, Egwuagu CE.

Invest Ophthalmol Vis Sci. 2004 Mar;45(3):872-8.PMID: 14985304 [PubMed - indexed for MEDLINE]Related articlesFree article